Suresh Katragadda (15 results)
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Seller: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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Seller: GreatBookPricesUK, Woodford Green, United KingdomGreatBookPricesUK
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Seller: preigu, Osnabrück, Germanypreigu
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Taschenbuch. Condition: Neu. AMINO ACID PRODRUGS OF ACYCLOVIR: OCULAR HERPES INFECTIONS | DESIGN OF AMINO ACID PRODRUGS OF ACYCLOVIR FOR IMPROVED BIOAVAILABILITY AND THERAPEUTIC ACTIVITY: UTILITY IN TREATING OCULAR HERPES INFECTIONS | Suresh Katragadda | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2009 | VDM Verlag Dr.… Müller | EAN 9783639151367 | Verantwortliche Person für die EU: OmniScriptum GmbH & Co. KG, Bahnhofstr. 28, 66111 Saarbrücken, info[at]akademikerverlag[dot]de | Anbieter: preigu.
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Seller: Juanpebooks, MIAMI, FL, U.S.A.Juanpebooks
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Seller: GreatBookPricesUK, Woodford Green, United KingdomGreatBookPricesUK
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Seller: Mispah books, Redhill, SURRE, United KingdomMispah books
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Seller: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
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Seller: PBShop.store UK, Fairford, GLOS, United KingdomPBShop.store UK
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PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
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Seller: moluna, Greven, Germanymoluna
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Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Katragadda SureshSuresh Katragadda, PhD: Graduated with PhD in Pharmaceutical Sciences at University of Missouri Kansas City (UMKC). Working as a NCD scientist I at Vertex Pharm…aceuticals Inc., Boston. Ashim K. Mitra, PhD: Graduated .
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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Infection with herpes simplex virus (HSV) is the single most frequent cause of corneal opacities. Current available therapy for HSV keratitis involves the use of trifluorothymidine, idoxuridine and vidarabine. However, one of major probl…ems associated with these drugs is their cytotoxicity. Acyclovir (ACV) with its selective mechanism of action can cause less cytotoxicity but its poor permeability across cellular barrier limits its utility. Thus, the development of a safe, long-acting, effective and stable topical antiviral drops that require less frequent dosing would represent a significant improvement. Recently design of prodrugs targeted to membrane transporters for improved efficacy and absorption proved highly successful. valacyclovir (VACV) is such a prodrug that increased the oral bioavailability of ACV by 3-5 fold in humans. Recently the presence of these transport systems on the corneal epithelium has been established in our laboratory. A series of novel water soluble amino acid ester prodrugs of ACV were thus synthesized. In conclusion more permeable, less cytotoxic Ser-acyclovir (SACV) exhibited excellent antiviral activity against HSV viruses.
