Refine your search

  • Books (38)

to

Custom price range (£)

to

S J Berkhout (38 results)

Author: 
Refine with Advanced Search
  • Language: English

    Published by Pearson, 2011

    • Softcover

    Seller: Chapter 1, Johannesburg, GAU, South AfricaChapter 1

    5-star seller
    Contact seller

    Condition: Used - Good

    £ 26.82

    £ 20.87 shipping 
    Ships from South Africa to U.S.A.

    Quantity: 1 available

    Add to basket

    Paperback. Condition: Good. 2nd Impression.The wraps are rubbed and marked. edge worn.interior clean. Due to weight postal adjustments may be required. Ek. Our orders are shipped using tracked courier delivery services.

  • More images

    Language: Dutch

    Published by Edu'Actief, 2006

    9060537289 / 9789060537282

    • Hardcover

    Seller: Bookbot, Prague, Czech RepublicBookbot

    5-star seller
    Contact seller

    Condition: Used - Fine

    £ 27.59

    £ 12.52 shipping 
    Ships from Czech Republic to U.S.A.

    Quantity: 1 available

    Hardcover. Condition: Fine. Leichte Gebrauchsspuren.

  • Published by Breda, Koninklijke Militaire Academie, 1898., 1898

    • Hardcover
    • First Edition

    Seller: Librarium of The Hague, The Hague, NetherlandsLibrarium of The Hague

    5-star seller
    Contact seller

    Condition: Used

    £ 23.22

    £ 29.22 shipping 
    Ships from Netherlands to U.S.A.

    Quantity: 1 available

    Add to basket

    Hardcover. 1st Edition. Royal octavo. Pp. 180; xviii, Appendix of tables, some folding, bound at end. HARDCOVER, bound in the original publisher's blue cloth and printed boards, old military institutional stamps to cover and title-page, old bookplate inside cover. In a very good condition. ~ FIRST EDITION. Text volume only, without the atlas. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (illustrator).…

  • More images

    Published by Breda, Koninklijke Militaire Academie, 1898., 1898

    • Hardcover
    • First Edition

    Seller: Librarium of The Hague, The Hague, NetherlandsLibrarium of The Hague

    5-star seller
    Contact seller

    Condition: Used

    £ 23.22

    £ 29.22 shipping 
    Ships from Netherlands to U.S.A.

    Quantity: 1 available

    Add to basket

    Hardcover. 1st Edition. Royal octavo. Pp. 315. Plus 20 (of 21) lithographic plates with numerous figures. HARDCOVER, bound in the original publisher's blue full cloth, bit marked, large gilt lettering and decorations, cloth inner hinges, silken endpapers, neat contemporary signature to first blank; old institutional stamp to verso of title. In a very good condition. ~ FIRST EDITION. Lacks one plate which is provided herewith in laser facsimile. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (illustrator). …

  • Language: English

    Published by Springer, 2015

    1493924311 / 9781493924318

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Hardcover

    Seller: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices

    5-star seller
    Contact seller

    Condition: New

    £ 102.90

    £ 1.96 shipping 
    Ships within U.S.A.

    Quantity: Over 20 available

    Condition: New.

  • Language: English

    Published by Springer, 2015

    1493924311 / 9781493924318

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Hardcover

    Seller: GreatBookPricesUK, Woodford Green, United KingdomGreatBookPricesUK

    5-star seller
    Contact seller

    Condition: New

    £ 100.14

    £ 15.00 shipping 
    Ships from United Kingdom to U.S.A.

    Quantity: Over 20 available

    Condition: New.

  • Language: English

    Published by Kluwer Academic Publishers, 1998

    0792352068 / 9780792352068

    • Softcover

    Seller: Kennys Bookshop and Art Galleries Ltd., Galway, GY, IrelandKennys Bookshop and Art Galleries Ltd.

    5-star seller
    Contact seller

    Condition: New

    £ 115.06

    £ 7.93 shipping 
    Ships from Ireland to U.S.A.

    Quantity: 15 available

    Condition: New. As we reach the end of the 20th century, the question of how to meet human needs and preferences while safeguarding the global environment is a concern facing humanity. This book reflects thinking on the necessary concepts, tools and instruments that are likely to help producers, consumers and governments to adjust their policies and practices. Editor(s): Vellinga, Pier; Berkhout, Frans; Gupta, Joyeeta. Series: Environment & Policy. Num Pages: 349 pages, biography. BIC Classification: JPQB; RN. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 240 x 160 x 19. Weight in Grams: 516. . 1998. Softcover reprint of the original 1st ed. 1998. Paperback. . . . . …

  • Language: English

    Published by Kluwer Academic Publishers, 1998

    0792351533 / 9780792351535

    • Hardcover

    Seller: Kennys Bookshop and Art Galleries Ltd., Galway, GY, IrelandKennys Bookshop and Art Galleries Ltd.

    5-star seller
    Contact seller

    Condition: New

    £ 117.04

    £ 7.93 shipping 
    Ships from Ireland to U.S.A.

    Quantity: 15 available

    Condition: New. Reflects the state of the art of thinking on the necessary concepts, tools and instruments likely to help producers, consumers and governments to adjust their policies and practices. This book covers theories and concepts, practical approaches and visions of industry and government. Editor(s): Vellinga, Pier; Berkhout, Frans; Gupta, Joyeeta. Series: Environment & Policy. Num Pages: 349 pages, biography. BIC Classification: JPQB; RNK. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 20. Weight in Grams: 691. . 1998. Hardback. . . . . …

  • Language: English

    Published by Springer, 2015

    1493924311 / 9781493924318

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Hardcover

    Seller: Books Puddle, Woodside, NY, U.S.A.Books Puddle

    4-star seller
    Contact seller

    Condition: New

    £ 133.19

    £ 2.97 shipping 
    Ships within U.S.A.

    Quantity: 4 available

    Condition: New. pp. 236.

  • Language: English

    Published by Springer, 2016

    1493948652 / 9781493948659

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Softcover

    Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

    5-star seller
    Contact seller

    Condition: New

    £ 107.37

    £ 29.22 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.…

  • Language: English

    Published by Springer, 2016

    1493948652 / 9781493948659

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Softcover

    Seller: preigu, Osnabrück, Germanypreigu

    5-star seller
    Contact seller

    Condition: New

    £ 82.13

    £ 58.44 shipping 
    Ships from Germany to U.S.A.

    Quantity: 5 available

    Taschenbuch. Condition: Neu. Gene Therapy for HIV and Chronic Infections | Ben Berkhout (u. a.) | Taschenbuch | xvi | Englisch | 2016 | Springer | EAN 9781493948659 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

  • Language: English

    Published by Springer, 2016

    1493948652 / 9781493948659

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Softcover

    Seller: Books Puddle, Woodside, NY, U.S.A.Books Puddle

    4-star seller
    Contact seller

    Condition: New

    £ 138.92

    £ 2.97 shipping 
    Ships within U.S.A.

    Quantity: 4 available

    Condition: New. pp. 236.

  • Condition: New

    £ 129.28

    £ 12.50 shipping 
    Ships from United Kingdom to U.S.A.

    Quantity: 2 available

    Hardcover. Condition: Brand New. 1st edition. 236 pages. 9.50x6.00x0.75 inches. In Stock.

  • Language: English

    Published by Kluwer Academic Publishers, 1998

    0792352068 / 9780792352068

    • Softcover

    Seller: Kennys Bookstore, Olney, MD, U.S.A.Kennys Bookstore

    5-star seller
    Contact seller

    Condition: New

    £ 143.93

    £ 7.81 shipping 
    Ships within U.S.A.

    Quantity: 15 available

    Condition: New. As we reach the end of the 20th century, the question of how to meet human needs and preferences while safeguarding the global environment is a concern facing humanity. This book reflects thinking on the necessary concepts, tools and instruments that are likely to help producers, consumers and governments to adjust their policies and practices. Editor(s): Vellinga, Pier; Berkhout, Frans; Gupta, Joyeeta. Series: Environment & Policy. Num Pages: 349 pages, biography. BIC Classification: JPQB; RN. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 240 x 160 x 19. Weight in Grams: 516. . 1998. Softcover reprint of the original 1st ed. 1998. Paperback. . . . . Books ship from the US and Ireland. …

  • Language: English

    Published by Kluwer Academic Publishers, 1998

    0792351533 / 9780792351535

    • Hardcover

    Seller: Kennys Bookstore, Olney, MD, U.S.A.Kennys Bookstore

    5-star seller
    Contact seller

    Condition: New

    £ 146.26

    £ 7.81 shipping 
    Ships within U.S.A.

    Quantity: 15 available

    Condition: New. Reflects the state of the art of thinking on the necessary concepts, tools and instruments likely to help producers, consumers and governments to adjust their policies and practices. This book covers theories and concepts, practical approaches and visions of industry and government. Editor(s): Vellinga, Pier; Berkhout, Frans; Gupta, Joyeeta. Series: Environment & Policy. Num Pages: 349 pages, biography. BIC Classification: JPQB; RNK. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 20. Weight in Grams: 691. . 1998. Hardback. . . . . Books ship from the US and Ireland. …

  • Language: English

    Published by Springer New York, 2015

    1493924311 / 9781493924318

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Hardcover

    Seller: Buchpark, Trebbin, GermanyBuchpark

    5-star seller
    Contact seller

    Condition: Used - Fine

    Original price: £ 79.72
    10% off

    Current price: £ 71.75

    £ 87.67 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Condition: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | This book centers  on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals.   Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990¿s. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.…

  • Condition: New

    £ 150.32

    £ 10.00 shipping 
    Ships from United Kingdom to U.S.A.

    Quantity: 1 available

    Paperback. Condition: Brand New. reprint edition. 252 pages. 9.25x6.10x0.60 inches. In Stock.

  • Language: English

    Published by Springer, 2015

    1493924311 / 9781493924318

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Hardcover

    Seller: GreatBookPricesUK, Woodford Green, United KingdomGreatBookPricesUK

    5-star seller
    Contact seller

    Condition: Used - As new

    £ 172.99

    £ 15.00 shipping 
    Ships from United Kingdom to U.S.A.

    Quantity: Over 20 available

    Condition: As New. Unread book in perfect condition.

  • Language: English

    Published by Springer, 2015

    1493924311 / 9781493924318

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Hardcover

    Seller: Mispah books, Redhill, SURRE, United KingdomMispah books

    4-star seller
    Contact seller

    Condition: Used - As new

    £ 165.00

    £ 25.00 shipping 
    Ships from United Kingdom to U.S.A.

    Quantity: 1 available

    Hardcover. Condition: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

  • Language: English

    Published by Springer, 2015

    1493924311 / 9781493924318

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Hardcover

    Seller: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices

    5-star seller
    Contact seller

    Condition: Used - As new

    £ 197.55

    £ 1.96 shipping 
    Ships within U.S.A.

    Quantity: Over 20 available

    Condition: As New. Unread book in perfect condition.

  • Language: English

    Published by Springer, 2016

    1493948652 / 9781493948659

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Softcover

    Seller: Mispah books, Redhill, SURRE, United KingdomMispah books

    4-star seller
    Contact seller

    Condition: Used - As new

    £ 227.00

    £ 25.00 shipping 
    Ships from United Kingdom to U.S.A.

    Quantity: 1 available

    Paperback. Condition: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

  • More images

    Published by Breda, Koninklijke Militaire Academie, 1898., 1898

    • Hardcover
    • First Edition

    Seller: Librarium of The Hague, The Hague, NetherlandsLibrarium of The Hague

    5-star seller
    Contact seller

    Condition: Used

    £ 46.44

    £ 29.22 shipping 
    Ships from Netherlands to U.S.A.

    Quantity: 1 available

    Add to basket

    Hardcover. 1st Edition. Royal octavo. Pp. 315. Plus 21 lithographic plates with numerous figures to each. One plate printed in fine collotype, showing the results of impacts of bullets with body. HARDCOVER, bound in contemporary cloth and marbled boards, very old small shelf tickets, old institutional stamp to half-title and title. In fine condition. ~ FIRST EDITION. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (illustrator).…

  • More images

    Published by Breda, Koninklijke Militaire Academie, 1900., 1900

    • Hardcover
    • First Edition

    Seller: Librarium of The Hague, The Hague, NetherlandsLibrarium of The Hague

    5-star seller
    Contact seller

    Condition: Used

    £ 50.31

    £ 29.22 shipping 
    Ships from Netherlands to U.S.A.

    Quantity: 1 available

    Add to basket

    Hardcover. 1st Edition. Crown quarto. Pp. vi, 169, comprising of tables and ballistic data. Plus a suite of 32 lithographic plates bound at end, with numerous illustrations to each plate. HARDCOVER, bound in contemporary calf and boards with the original printed wrappers laid-down, cloth French corners, small old shelf ticket to spine, faded old military institutional stamp to cover; bit shabby, spine bit rubbed in places. In a very good condition. Practically unused, mostly unopened. ~ FIRST EDITION. Very rare. Appendix volume with tables and plates. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (illustrator).…

  • More images

    Published by Breda, Koninklijke Militaire Academie, 1897., 1897

    • Hardcover
    • First Edition

    Seller: Librarium of The Hague, The Hague, NetherlandsLibrarium of The Hague

    5-star seller
    Contact seller

    Condition: Used

    £ 61.92

    £ 29.22 shipping 
    Ships from Netherlands to U.S.A.

    Quantity: 1 available

    Add to basket

    Hardcover. 1st Edition. Two volumes. Royal octavo. Pp. xii, 196. Plus some folding charts. With corrections and annotations in very neat contemporary hand to some leaves. HARDCOVER, bound in contemporary cloth and marbled boards, shelf ticket to spine, old institutional stamp to title. In good condition. [AND:] Atlas. Quarto, comprising of title-page and 24 double-page lithographic plates with numerous illustrations to each. HARDCOVER, bound in the original publisher's cloth and printed boards, old stamp and shelf ticket, cover trifle soiled. In a very good condition, fine interior. ~ FIRST EDITION. Rare complete set which includes the Atlas. This comprises of numerous fine and very detailed technical illustrations of guns and cannons and their parts, accompanied by nomenclatures and extended explanations and measurements. Meticulously executed and lithographed in its entirety. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (illustrator).…

  • More images

    Condition: Used

    £ 85.14

    £ 29.22 shipping 
    Ships from Netherlands to U.S.A.

    Quantity: 1 available

    Add to basket

    Hardcover. 1st Edition. Two volumes. I. Text: Royal octavo. Pp. viii, 215. Tables. HARDCOVER, bound in the original publisher's cloth and printed boards, old small shelf tickets to spine, old institutional stamps to cover, prelims and title, some underlining, corrections and shoulder annotations. In good condition. II. Atlas: Quarto. Pp. Title-page, (i), and 16 double-page lithographic plates with numerous illustrations to each. HARDCOVER, bound in the original publisher's cloth and printed boards, old military institutional stamp on cover and two contemporary, rather decorative private stamps to title-page. In a very good condition. ~ FIRST EDITION. Very rare complete set. The Atlas comprises of numerous fine and very detailed technical illustrations of guns and cannons and their parts, accompanied by nomenclatures and extended explanations and measurements. Meticulously executed and lithographed in its entirety. One page in the text volume is heavily annotated in margins in contemporary hand, shading some light on the thought process of military cadets at the time. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (illustrator).…

  • Language: English

    Published by Springer, 2016

    1493948652 / 9781493948659

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Softcover
    • Print on Demand

    Seller: Brook Bookstore On Demand, Napoli, NA, ItalyBrook Bookstore On Demand

    5-star seller
    Contact seller

    Condition: New

    £ 74.17

    £ 25.05 shipping 
    Ships from Italy to U.S.A.

    Quantity: Over 20 available

    Condition: new. Questo è un articolo print on demand.

  • Language: English

    Published by Springer, 2015

    1493924311 / 9781493924318

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Hardcover
    • Print on Demand

    Seller: Brook Bookstore On Demand, Napoli, NA, ItalyBrook Bookstore On Demand

    5-star seller
    Contact seller

    Condition: New

    £ 74.17

    £ 28.39 shipping 
    Ships from Italy to U.S.A.

    Quantity: Over 20 available

    Condition: new. Questo è un articolo print on demand.

  • Language: English

    Published by Springer New York Okt 2016, 2016

    1493948652 / 9781493948659

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Softcover
    • Print on Demand

    Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

    5-star seller
    Contact seller

    Condition: New

    £ 92.01

    £ 19.20 shipping 
    Ships from Germany to U.S.A.

    Quantity: 2 available

    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology. 252 pp. Englisch.…

  • Language: English

    Published by Springer New York Mrz 2015, 2015

    1493924311 / 9781493924318

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Hardcover
    • Print on Demand

    Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

    5-star seller
    Contact seller

    Condition: New

    £ 92.01

    £ 19.20 shipping 
    Ships from Germany to U.S.A.

    Quantity: 2 available

    Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology. 252 pp. Englisch. …

  • Language: English

    Published by Springer New York, 2016

    1493948652 / 9781493948659

    Series: Book 65 of 490 - Advances in Experimental Medicine and Biology

    • Softcover
    • Print on Demand

    Seller: moluna, Greven, Germanymoluna

    5-star seller
    Contact seller

    Condition: New

    £ 79.35

    £ 40.90 shipping 
    Ships from Germany to U.S.A.

    Quantity: Over 20 available

    Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This book focuses on gene therapy and gene transfer approaches to prevent or treat chronoic virus infections Discusses a collection of molecular antiviral strategies (ribozymes, RNAi, RNAu, aptamers, etcCo-published with the American Societ. …