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Published by Royal Society of Chemistry, 2013
ISBN 10: 1849733848 ISBN 13: 9781849733847
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Published by Royal Society of Chemistry, 2010
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Published by Royal Society of Chemistry, 2010
ISBN 10: 1849730040 ISBN 13: 9781849730044
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Published by Royal Society of Chemistry, 2013
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Published by Royal Society of Chemistry, 2010
ISBN 10: 1849730040 ISBN 13: 9781849730044
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Published by Royal Society of Chemistry, GB, 2013
ISBN 10: 1849733848 ISBN 13: 9781849733847
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Hardback. Condition: New. The aim of this book is to provide the scientific background to using the formation of chemical categories, or groups, of molecules to allow for read-across i.e. the prediction of toxicity from chemical structure. It covers the scientific basis for this approach to toxicity prediction including the methods to group compounds (structural analogues and / or similarity, mechanism of action) and the tools to achieve this. The approaches to perform read-across within a chemical category are also described.Chemical Toxicity Prediction provides concise practical guidance for those wishing to apply these methods (in risk / hazard assessment) and will be illustrated with case studies. This is the first book that addresses the concept of category formation and read-across for toxicity prediction specifically. This topic has really taken off in the past few years due to concerns over dealing with the REACH legislation and also due to the availability of the OECD (Q)SAR Toolbox. Much (lengthy and complex) guidance is available on category formation e.g. from the OECD and, to a lesser extent, the European Chemicals Agency but there is no one single source of information that covers all techniques in a concise user-friendly format.
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Published by Royal Society of Chemistry, Cambridge, 2013
ISBN 10: 1849733848 ISBN 13: 9781849733847
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Hardcover. Condition: new. Hardcover. The aim of this book is to provide the scientific background to using the formation of chemical categories, or groups, of molecules to allow for read-across i.e. the prediction of toxicity from chemical structure. It covers the scientific basis for this approach to toxicity prediction including the methods to group compounds (structural analogues and / or similarity, mechanism of action) and the tools to achieve this. The approaches to perform read-across within a chemical category are also described.Chemical Toxicity Prediction provides concise practical guidance for those wishing to apply these methods (in risk / hazard assessment) and will be illustrated with case studies. This is the first book that addresses the concept of category formation and read-across for toxicity prediction specifically. This topic has really taken off in the past few years due to concerns over dealing with the REACH legislation and also due to the availability of the OECD (Q)SAR Toolbox. Much (lengthy and complex) guidance is available on category formation e.g. from the OECD and, to a lesser extent, the European Chemicals Agency but there is no one single source of information that covers all techniques in a concise user-friendly format. The aim of this book is to provide the scientific background to using the formation of chemical categories, or groups, of molecules to allow for read-across i.e. the prediction of toxicity from chemical structure. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
Language: English
Published by Royal Society of Chemistry, 2010
ISBN 10: 1849730040 ISBN 13: 9781849730044
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