Pathogenesis Fibrosis (35 results)
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Published by LAP LAMBERT Academic Publishing 2013-08-08, 2013
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Hardback or Cased Book. Condition: New. Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis. Book.
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Taschenbuch. Condition: Neu. Pathogenesis of Pulmonary Fibrosis and New Approaches to the Therapy | Neurotropic Drugs Modulate the Activity of Stem and Progenitor Cells | Evgenii Skurikhin (u. a.) | Taschenbuch | 68 S. | Englisch | 2013 | LAP LAMBERT Academic Publishing | EAN 9783659308536 | Verantwortliche Person für die EU: pr…eigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
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Taschenbuch. Condition: Neu. Role of TGF-¿ in the pathogenesis of Oral Submucous Fibrosis | Ann Tryphena E. T (u. a.) | Taschenbuch | Englisch | 2023 | LAP LAMBERT Academic Publishing | EAN 9786206752349 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | A…nbieter: preigu.
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03. Condition: Wie neu. 1994. 165 pp., 111 figs., 16 tabs., softcover Sprache: Deutsch.
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Published by LAP LAMBERT Academic Publishing Aug 2013, 2013
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The model of irreversible bleomycin-induced pulmonary fibrosis shows that simultaneously with inflammatory cells in interstitial lung tissue of mice C57BL/6 cells with the phenotype Lin-, Sca-1+, c-Kit+, CD34- (HSCs) and hematopoiet…ic progenitor cells (Lin-, Sca-1+, c-Kit+) are identified. During the phase of inflammation, HSCs of bleomycin lungs are characterized with high mitotic activity and the ability to differentiate into myeloid cell. Interstitial infiltration of alveolar ducts and alveoli by immature hematopoietic cells is accompanied by an increase in the level of multipotent progenitor cells in bone marrow and blood. Two subpopulations of mesenchymal stem cells (MSCs): 1 - (CD45-, CD73+, CD90+, CD44+, CD106+) and 2 - (CD45-, CD73+, CD90+, CD31-, CD34-) are defined in the parenchyma of bleomycin lungs upon the collagen deposition and fibroblast progenitor cells admission. MSCs are characterized by high mitotic activity and differentiation in the direction of fibroblast cells, while chondrogenesis and bone formation is disrupted. Neurotropic drugs modulate the activity of endogenous stem cells and thereby they can influence on the inflammation and fibrosis in lungs of mice. 68 pp. Englisch.
Language: English
Published by LAP LAMBERT Academic Publishing Jul 2023, 2023
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This textbook emphasises on the role of TGF-beta in the pathogenesis of Oral Submucous Fibrosis. Oral submucous fibrosis (OSMF) is a chronic disease and a well-recognized potentially malignant disorder of the oral cavity characteriz…ed by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. Various epidemiological studies and histopathological effects on fibroblast and keratinocytes support the chewing of areca nut as one of the most important risk factors for OSMF. In OSMF there is excessive accumulation of collagen in the lamina propria. Increased collagen production and decreased collagen degradation results in increased collagen deposition in the oral tissue, leading to fibrosis. TGF- beta is a key regulator of Extra- cellular matrix (ECM) assembly and remodelling. TGF-beta modulates both collagen production and decreased degradation through various mechanisms. OSMF can be managed by abstinence of habits, along with some possible interventions like anti-inflammatory or immunomodulatory drugs, by blocking transforming growth factor-beta (TGF-beta) action, use of copper chelators and collagenase activators. 76 pp. Englisch.
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Condition: New. Print on Demand pp. 276.
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: E.T ANN TRYPHENADr. E.T.Ann Tryphena BDS, MDS(Oral Pathology) is an Assistant Professor in the Department of Oral Pathology and Microbiology, Sri Ramakrishna Dental College & Hospital, Coimbatore, Tamil… Nadu, India. She has a passion.
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Condition: New. PRINT ON DEMAND pp. 276.
Language: English
Published by LAP LAMBERT Academic Publishing Aug 2013, 2013
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The model of irreversible bleomycin-induced pulmonary fibrosis shows that simultaneously with inflammatory cells in interstitial lung tissue of mice C57BL/6 cells with the phenotype Lin-, Sca-1+, c-Kit+, CD34- (HSCs) and hematopoietic p…rogenitor cells (Lin-, Sca-1+, c-Kit+) are identified. During the phase of inflammation, HSCs of bleomycin lungs are characterized with high mitotic activity and the ability to differentiate into myeloid cell. Interstitial infiltration of alveolar ducts and alveoli by immature hematopoietic cells is accompanied by an increase in the level of multipotent progenitor cells in bone marrow and blood. Two subpopulations of mesenchymal stem cells (MSCs): 1 - (CD45-, CD73+, CD90+, CD44+, CD106+) and 2 - (CD45-, CD73+, CD90+, CD31-, CD34-) are defined in the parenchyma of bleomycin lungs upon the collagen deposition and fibroblast progenitor cells admission. MSCs are characterized by high mitotic activity and differentiation in the direction of fibroblast cells, while chondrogenesis and bone formation is disrupted. Neurotropic drugs modulate the activity of endogenous stem cells and thereby they can influence on the inflammation and fibrosis in lungs of mice.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 68 pp. Englisch.
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The model of irreversible bleomycin-induced pulmonary fibrosis shows that simultaneously with inflammatory cells in interstitial lung tissue of mice C57BL/6 cells with the phenotype Lin-, Sca-1+, c-Kit+, CD34- (HSCs) and hematopoietic pr…ogenitor cells (Lin-, Sca-1+, c-Kit+) are identified. During the phase of inflammation, HSCs of bleomycin lungs are characterized with high mitotic activity and the ability to differentiate into myeloid cell. Interstitial infiltration of alveolar ducts and alveoli by immature hematopoietic cells is accompanied by an increase in the level of multipotent progenitor cells in bone marrow and blood. Two subpopulations of mesenchymal stem cells (MSCs): 1 - (CD45-, CD73+, CD90+, CD44+, CD106+) and 2 - (CD45-, CD73+, CD90+, CD31-, CD34-) are defined in the parenchyma of bleomycin lungs upon the collagen deposition and fibroblast progenitor cells admission. MSCs are characterized by high mitotic activity and differentiation in the direction of fibroblast cells, while chondrogenesis and bone formation is disrupted. Neurotropic drugs modulate the activity of endogenous stem cells and thereby they can influence on the inflammation and fibrosis in lungs of mice.
