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PAP. Condition: New. New Book. Shipped from UK. Established seller since 2000.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Book 5 of 6: Springer Series in Pharmaceutical StatisticsSeller: PBShop.store UK, Fairford, GLOS, United Kingdom
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PAP. Condition: New. New Book. Shipped from UK. Established seller since 2000.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials (Springer Series in Pharmaceutical Statistics)
Book 5 of 6: Springer Series in Pharmaceutical StatisticsSeller: Books From California, Simi Valley, CA, U.S.A.
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hardcover. Condition: Very Good. Cover and edges may have some wear. Mild to Moderate creasing / bending to covers and pages.
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Condition: As New. Unread book in perfect condition.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Book 5 of 6: Springer Series in Pharmaceutical StatisticsLanguage: English
Published by Springer Nature Switzerland AG, CH, 2021
ISBN 10: 3030495302 ISBN 13: 9783030495305
Seller: Rarewaves.com USA, London, LONDO, United Kingdom
Seller rating 5 out of 5 stars
Paperback. Condition: New. 2020 ed.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials (Springer Series in Pharmaceutical Statistics)
Book 5 of 6: Springer Series in Pharmaceutical StatisticsSeller: Ria Christie Collections, Uxbridge, United Kingdom
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Book 5 of 6: Springer Series in Pharmaceutical StatisticsSeller: GreatBookPricesUK, Woodford Green, United Kingdom
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Hardcover. Condition: Very Good. 1. Auflage. Unread, with a mimimum of shelfwear. Immediately dispatched from Germany.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Book 5 of 6: Springer Series in Pharmaceutical StatisticsSeller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
Condition: As New. Unread book in perfect condition.
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Condition: As New. Unread book in perfect condition.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials (Springer Series in Pharmaceutical Statistics)
Book 5 of 6: Springer Series in Pharmaceutical StatisticsSeller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 81.52
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Book 5 of 6: Springer Series in Pharmaceutical StatisticsSeller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
Condition: New.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Book 5 of 6: Springer Series in Pharmaceutical StatisticsLanguage: English
Published by Springer, Berlin|Springer International Publishing|Springer, 2021
ISBN 10: 3030495302 ISBN 13: 9783030495305
Condition: New. This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for samp.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Book 5 of 6: Springer Series in Pharmaceutical StatisticsSeller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
Condition: As New. Unread book in perfect condition.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Book 5 of 6: Springer Series in Pharmaceutical StatisticsLanguage: English
Published by Springer Nature Switzerland AG, CH, 2021
ISBN 10: 3030495302 ISBN 13: 9783030495305
Paperback. Condition: New. 2020 ed.
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Condition: New. 1st ed. 2020 edition NO-PA16APR2015-KAP.
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Hardcover. Condition: Brand New. 396 pages. 9.25x6.10x1.02 inches. In Stock.
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Taschenbuch. Condition: Neu. Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials | Meinhard Kieser | Taschenbuch | xiv | Englisch | 2021 | Springer | EAN 9783030495305 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Appropriate calculation of the required sample size is crucial for the success of clinical trials. At the same time, a sample size that is too small or too large is problematic due to ethical, scientific, and economic reasons. Therefore, state-of-the art methods are required when planning clinical trials. Part I describes a general framework for deriving sample size calculation procedures. This enables an understanding of the common principles underlying the numerous methods presented in the following chapters. Part II addresses the fixed sample size design, where the required sample size is determined in the planning stage and is not changed afterwards. It covers sample size calculation methods for superiority, non-inferiority, and equivalence trials, as well as comparisons between two and more than two groups. A wide range of further topics is discussed, including sample size calculation for multiple comparisons, safety assessment, and multi-regional trials. There is often some uncertainty about the assumptions to be made when calculating the sample size upfront. Part III presents methods that allow to modify the initially specified sample size based on new information that becomes available during the ongoing trial. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses. The application is illustrated using numerous clinical trial examples, and software code implementing the methods is provided.The book offers theoretical background and practical advice for biostatisticians and clinicians from the pharmaceutical industry and academia who are involved in clinical trials. Covering basic as well as more advanced and recently developed methods, it is suitable forbeginners, experienced applied statisticians, and practitioners. To gain maximum benefit, readers should be familiar with introductory statistics. The content of this book has been successfully used for courses on the topic.
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Appropriate calculation of the required sample size is crucial for the success of clinical trials. At the same time, a sample size that is too small or too large is problematic due to ethical, scientific, and economic reasons. Therefore, state-of-the art methods are required when planning clinical trials. Part I describes a general framework for deriving sample size calculation procedures. This enables an understanding of the common principles underlying the numerous methods presented in the following chapters. Part II addresses the fixed sample size design, where the required sample size is determined in the planning stage and is not changed afterwards. It covers sample size calculation methods for superiority, non-inferiority, and equivalence trials, as well as comparisons between two and more than two groups. A wide range of further topics is discussed, including sample size calculation for multiple comparisons, safety assessment, and multi-regional trials. There is often some uncertainty about the assumptions to be made when calculating the sample size upfront. Part III presents methods that allow to modify the initially specified sample size based on new information that becomes available during the ongoing trial. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses. The application is illustrated using numerous clinical trial examples, and software code implementing the methods is provided.The book offers theoretical background and practical advice for biostatisticians and clinicians from the pharmaceutical industry and academia who are involved in clinical trials. Covering basic as well as more advanced and recently developed methods, it is suitable forbeginners, experienced applied statisticians, and practitioners. To gain maximum benefit, readers should be familiar with introductory statistics. The content of this book has been successfully used for courses on the topic.
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Paperback. Condition: Brand New. 410 pages. 9.25x6.10x0.93 inches. In Stock. This item is printed on demand.
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Condition: new. Questo è un articolo print on demand.
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Condition: new. Questo è un articolo print on demand.
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Book 5 of 6: Springer Series in Pharmaceutical StatisticsLanguage: English
Published by Springer International Publishing, Springer Nature Switzerland Nov 2020, 2020
ISBN 10: 3030495272 ISBN 13: 9783030495275
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Seller rating 5 out of 5 stars
Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Appropriate calculation of the required sample size is crucial for the success of clinical trials. At the same time, a sample size that is too small or too large is problematic due to ethical, scientific, and economic reasons. Therefore, state-of-the art methods are required when planning clinical trials. Part I describes a general framework for deriving sample size calculation procedures. This enables an understanding of the common principles underlying the numerous methods presented in the following chapters. Part II addresses the fixed sample size design, where the required sample size is determined in the planning stage and is not changed afterwards. It covers sample size calculation methods for superiority, non-inferiority, and equivalence trials, as well as comparisons between two and more than two groups. A wide range of further topics is discussed, including sample size calculation for multiple comparisons, safety assessment, and multi-regional trials. There is often some uncertainty about the assumptions to be made when calculating the sample size upfront. Part III presents methods that allow to modify the initially specified sample size based on new information that becomes available during the ongoing trial. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses. The application is illustrated using numerous clinical trial examples, and software code implementing the methods is provided.The book offers theoretical background and practical advice for biostatisticians and clinicians from the pharmaceutical industry and academia who are involved in clinical trials. Covering basic as well as more advanced and recently developed methods, it is suitable forbeginners, experienced applied statisticians, and practitioners. To gain maximum benefit, readers should be familiar with introductory statistics. The content of this book has been successfully used for courses on the topic. 412 pp. Englisch.
