Induced Pluripotent Stem Cells (197 results)

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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Induced Pluripotent Stem (iPS) cells are mature cells that have been genetically reprogrammed so that they return to their embryonic state. It is not yet known if iPS stem cells and embryonic stem cells differ significantly. Today many fundamental belief systems in biology are shifting towards accepting that mature body cells can be reverted to an embryonic state without the help of eggs or embryos. With their changed identities, iPS cells are then ready to serve as new tools for research in the fields of disease pathogenesis, drug discovery, oncology, and cell transplantation. One example of this would be using iPS from a patient's mature cells to repair damaged tissue; it is thought that there would be very low incidence of rejection of the 'new' tissue in these cases. For the last four years, this therapeutic promise has been studied by hundreds of researchers worldwide in an effort to understand the ability of these cells to reverse their biological clocks.…

Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic 'memories' of what they were that can affect reprogramming. This book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson's disease and Vanishing White Matter (VWM).…

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Taschenbuch. Condition: Neu. Induced Pluripotent Stem Cells | Turning iPS cells into a new working liver | Edward R. Miller-Jones | Taschenbuch | Englisch | 2026 | OmniScriptum | EAN 9786130134945 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. …

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Taschenbuch. Condition: Neu. Turning human skin cells into early-stage sperm cells | A novel in vivo transplantation approach using induced pluripotent stem cells and the mouse testis niche | Jens Durruthy-Durruthy | Taschenbuch | Englisch | 2018 | Südwestdeutscher Verlag für Hochschulschriften | EAN 9783838138824 | Verantwortliche Person für die EU: Südwestdt. Verl. f. Hochschulschrift., Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.…

Taschenbuch. Condition: Neu. Induced Pluripotent Stem Cells | Sibel Yildirim | Taschenbuch | SpringerBriefs in Stem Cells | viii | Englisch | 2011 | Springer | EAN 9781461422051 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

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Condition: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic ¿memories¿ of what they were that can affect reprogramming. This book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson¿s disease and Vanishing White Matter (VWM).¿.…

Condition: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher | Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic ¿memories¿ of what they were that can affect reprogramming. This book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson¿s disease and Vanishing White Matter (VWM).¿.…

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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Stem cells have the ability to differentiate into all types of cells within the body, thus have great therapeutic potential for regenerative medicine to treat complicated disorders, like Parkinson's disease and spinal cord injury. There will also be many applications in drug development. However, several roadblocks, such as safety issues and low efficiency of pluripotent stem cell (PSC) line derivation need to be resolved before their clinical application. This thesis focuses on these two areas, so as to find methods to overcome the limitation. It covers deriving embryonic stem cells (ESCs) from several different species and reports an efficient system to generate induced pluripotent stem cells (iPSCs), and the first iPSC mice in the world. The results in this thesis confirm that somatic cells can be fully reprogrammed with the four Yamanaka factors. In addition, we have found that the Dlk1-Dio3 region can be a potential molecular marker to distinguish the fully reprogrammed iPSCs from partially reprogrammed ones. All of these results will help improve the safety of PSCs in the clinical applications and increase the current low induction efficiency of their production.…

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Hardcover. Condition: Brand New. 2014 edition. 92 pages. 8.00x6.00x0.25 inches. In Stock.