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Published by Humana Press, New York, 2009
ISBN 10: 1603273344 ISBN 13: 9781603273343
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Condition: New. pp. 302.
Condition: New. 2016. Paperback. . . . . .
Taschenbuch. Condition: Neu. Functional Selectivity of G Protein-Coupled Receptor Ligands | New Opportunities for Drug Discovery | Kim Neve | Taschenbuch | The Receptors | x | Englisch | 2016 | Humana | EAN 9781493961160 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Condition: Sehr gut. Zustand: Sehr gut | Seiten: 292 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
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Published by Humana Press Inc., Totowa, NJ, 2009
ISBN 10: 1603273344 ISBN 13: 9781603273343
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Hardcover. Condition: new. Hardcover. Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse profile. Functional selectivity has profound implications for drug development, for chemical biology, and for the design of experiments to characterize receptor function. In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. This exciting, comprehensive, and future-oriented volume includes chapters that focus on theoretical and mechanistic aspects of functional selectivity and that cut across subfamilies of GPCRs. Additional chapters focus on subfamilies of therapeutically relevant receptors where there is considerable evidence of ligand functional selectivity. Accessible and authoritative, Functional Selectivity of G Protein-Coupled Receptors is a valuable educational tool and reference source for students and scientists interested in drug development, chemical biology, and GPCR function. In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
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Condition: New. In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. Editor(s): Neve, Kim. Series: The Receptors. Num Pages: 292 pages, biography. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 20. Weight in Grams: 558. . 2009. Hardback. . . . .
Condition: New. Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at path.
Language: English
Published by Humana Press Mär 2009, 2009
ISBN 10: 1603273344 ISBN 13: 9781603273343
Seller: AHA-BUCH GmbH, Einbeck, Germany
Buch. Condition: Neu. Neuware - Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse profile. Functional selectivity has profound implications for drug development, for chemical biology, and for the design of experiments to characterize receptor function. In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. This exciting, comprehensive, and future-oriented volume includes chapters that focus on theoretical and mechanistic aspects of functional selectivity and that cut across subfamilies of GPCRs. Additional chapters focus on subfamilies of therapeutically relevant receptors where there is considerable evidence of ligand functional selectivity. Accessible and authoritative, Functional Selectivity of G Protein-Coupled Receptors is a valuable educational tool and reference source for students and scientists interested in drug development, chemical biology, and GPCR function.
Hardcover. Condition: Brand New. 1st edition. 290 pages. 9.25x6.25x0.75 inches. In Stock.
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Condition: New. In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. Editor(s): Neve, Kim. Series: The Receptors. Num Pages: 292 pages, biography. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 20. Weight in Grams: 558. . 2009. Hardback. . . . . Books ship from the US and Ireland.
Seller: Mispah books, Redhill, SURRE, United Kingdom
Hardcover. Condition: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
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Language: English
Published by Springer, 2009
Seller: Books in my Basket, New Delhi, India
Hardcover. Condition: New. ISBN:9781603273343.
Condition: new. Questo è un articolo print on demand.
Language: English
Published by Humana Press Aug 2016, 2016
ISBN 10: 1493961160 ISBN 13: 9781493961160
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse profile. Functional selectivity has profound implications for drug development, for chemical biology, and for the design of experiments to characterize receptor function. In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. This exciting, comprehensive, and future-oriented volume includes chapters that focus on theoretical and mechanistic aspects of functional selectivity and that cut across subfamilies of GPCRs. Additional chapters focus on subfamilies of therapeutically relevant receptors where there is considerable evidence of ligand functional selectivity. Accessible and authoritative, Functional Selectivity of G Protein-Coupled Receptors is a valuable educational tool and reference source for students and scientists interested in drug development, chemical biology, and GPCR function. 304 pp. Englisch.
Seller: moluna, Greven, Germany
Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at path.
Condition: New. Print on Demand pp. 302.