Formulation Methylprednisolone Colon Targeted by Kumar Vasanth (11 results)

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Taschenbuch. Condition: Neu. Formulation Of Methylprednisolone Colon Targeted Tablets | Vasanth Kumar (u. a.) | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2013 | LAP Lambert Academic Publishing | EAN 9783659348686 | Verantwortliche Person für die EU: OmniScriptum GmbH & Co. KG, Bahnhofstr. 28, 66111 Saarbrücken, info[at]akademikerverlag[dot]de | Anbieter: preigu. …

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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The intent of current investigation is to make colon targeting methylprednisolone compression coated tablets using time dependent polymer hydroxypropyl methylcellulose and pH sensitive polymer Eudragit S100 that retard the liberation of drug in upper gastro intestinal system and also show progressive release in colon. The prepared formulations were optimized using dissolution tests and evaluated for colonic delivery by x-ray imaging and pharmacokinetic studies in healthy humans. The optimized formulation of methylprednisolone showed 10.52±0.68% in the initial lag period of 5 h followed by progressive release up to 101.43±3.33% for 24 h. The x-ray imaging study in human volunteers illustrated that the tablets arrived to colon with no loss of integrity in the upper gastrointestinal tract. Cmax of colon targeted compression coated tablets was 10324.83 ng/ml at Tmax 10 h which clearly indicates the capability of compression coated tablets to give colon targeting.…

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kumar VasanthVasanth Kumar is a post graduate student doing his Master of pharmacy in Pharmaceutical at Jangaon Institute of Pharmaceutical Sciences, Kakatiya University, Warangal, Andhra Pradesh. After completing his graduation in t. …