Experimental Models Multiple Sclerosis (15 results)
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Language: English
Published by Südwestdeutscher Verlag für Hochschulschriften, 2015
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Taschenbuch. Condition: Neu. Oxidative Tissue Injury in Experimental Models of Multiple Sclerosis | Cornelia Schuh | Taschenbuch | Englisch | 2015 | Südwestdeutscher Verlag für Hochschulschriften | EAN 9783838139357 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preig…u[dot]de | Anbieter: preigu.
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Condition: Used. pp. 932.
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Condition: New. This is the only title on experimental models of multiple sclerosisPreface by Ehud Lavi and Cris S. Constantinescu PART A - EXPERIMENTAL ALLERGIC (AUTOIMMUNE) ENCEPHALOMYELITIS (EAE): EAE: history, clinical signs, and disease course.- Induction .
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Hardcover. Condition: Brand New. 1st edition. 901 pages. 9.50x6.25x1.75 inches. In Stock.
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Buch. Condition: Neu. Neuware - Multiple Sclerosis (MS) is an enigmatic immune mediated disease of the central nervous system that affects about 350,000 individuals in the US, and many more around the world. The mechanism of this disease is largely unknown and there is no cure for it. However, there are several well-characterize…d experimental animal models that help us understand and speculate about potential mechanisms of pathology in this disease. Many of the experimental therapies designed for this disease rely on testing the drugs in animal models before using it in clinical trials. This book combines for the first time the different experimental models for MS (including immune-mediated and viral) under one roof, and highlights aspects that are different or shared among these experimental models. It's aim is to improve our understanding of this devastating disease and help us think about potential additional therapies for it.
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Language: English
Published by Südwestdeutscher Verlag Für Hochschulschriften Feb 2015, 2015
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Multiple sclerosis (MS) is a chronic disease of the central nervous system. A number of different animal models of MS contributed to a better understanding of MS pathology. Additionally, experimental models enabled the development o…f immune-modulatory therapies for MS patients. In recent years, growing evidence for a major role of oxidative injury in demyelination and neurodegeneration in MS has been emerging. Hence, we aimed to characterise the nature and the extent of oxidative damage in different experimental models in comparison to MS. For this purpose, we emphasised the expression of enzymes involved in reactive species production and the accumulation of oxidised phospholipids and iron, which is a potential amplifier of oxidative damage. The different animal models were triggered by diverse inflammatory mechanisms, each representing distinct aspects of MS pathology. The presented study reports a diverging extent of oxidative injury and underlying mechanisms in different models for inflammatory demyelination. 180 pp. Englisch.
Language: English
Published by Südwestdeutscher Verlag für Hochschulschriften, 2015
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Schuh CorneliaCornelia Schuh, PhD Postdoc at the Paracelsus Medical University in Salzburg in the Institute of Experimental and Clinical Cell Therapy PhD study at the Medical University of Vienna in the… Centre for Brain Research, S.
Language: English
Published by Südwestdeutscher Verlag Für Hochschulschriften Feb 2015, 2015
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Multiple sclerosis (MS) is a chronic disease of the central nervous system. A number of different animal models of MS contributed to a better understanding of MS pathology. Additionally, experimental models enabled the development of im…mune-modulatory therapies for MS patients. In recent years, growing evidence for a major role of oxidative injury in demyelination and neurodegeneration in MS has been emerging. Hence, we aimed to characterise the nature and the extent of oxidative damage in different experimental models in comparison to MS. For this purpose, we emphasised the expression of enzymes involved in reactive species production and the accumulation of oxidised phospholipids and iron, which is a potential amplifier of oxidative damage. The different animal models were triggered by diverse inflammatory mechanisms, each representing distinct aspects of MS pathology. The presented study reports a diverging extent of oxidative injury and underlying mechanisms in different models for inflammatory demyelination.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 180 pp. Englisch.
Language: English
Published by Südwestdeutscher Verlag Für Hochschulschriften, 2015
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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Multiple sclerosis (MS) is a chronic disease of the central nervous system. A number of different animal models of MS contributed to a better understanding of MS pathology. Additionally, experimental models enabled the development of imm…une-modulatory therapies for MS patients. In recent years, growing evidence for a major role of oxidative injury in demyelination and neurodegeneration in MS has been emerging. Hence, we aimed to characterise the nature and the extent of oxidative damage in different experimental models in comparison to MS. For this purpose, we emphasised the expression of enzymes involved in reactive species production and the accumulation of oxidised phospholipids and iron, which is a potential amplifier of oxidative damage. The different animal models were triggered by diverse inflammatory mechanisms, each representing distinct aspects of MS pathology. The presented study reports a diverging extent of oxidative injury and underlying mechanisms in different models for inflammatory demyelination.
