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Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Language: English
Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Published by VDM Verlag Dr. Mïż½ller 2008-11-19, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Language: English
Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Language: English
Published by VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Language: English
Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Kartoniert / Broschiert. Condition: New. KLF6 is a ubiquitously expressed Krueppel-liketranscription factor whose role in vitro and in vivorole has not been fully identified. Like othermembers of the Krueppel-like family, KLF6 contains aconserved C-terminal three zinc finger .
Language: English
Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Taschenbuch. Condition: Neu. Regulation of the Krüppel-like Factor 6 Tumor Suppressor | Ras Promotes Cancer Cell Growth via Alternative Splicing-Mediated Inactivation of KLF6 | Steven Yea | Taschenbuch | Kartoniert / Broschiert | Englisch | 2008 | VDM Verlag Dr. Müller | EAN 9783639103359 | Verantwortliche Person für die EU: OmniScriptum GmbH & Co. KG, Bahnhofstr. 28, 66111 Saarbrücken, info[at]akademikerverlag[dot]de | Anbieter: preigu.
Language: English
Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Add to basketPAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
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Published by VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Language: English
Published by VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Language: English
Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639103351 ISBN 13: 9783639103359
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - KLF6 is a ubiquitously expressed Krüppel-liketranscription factor whose role in vitro and in vivorole has not been fully identified. Like othermembers of the Krüppel-like family, KLF6 contains aconserved C-terminal three zinc finger DNA-bindingdomain (C2H2 motifs) and a unique N-terminaltransactivation domain. KLF6 directly binds DNA at GCbox promoter elements. Transcriptional targets ofKLF6 include collagen 1, transforming growth factorbeta 1 (TGF 1), types I and II TGF receptors,urokinase type plasminogen activator (uPA), and thehuman immunodeficiency virus long terminal repeat(HIV-1 LTR). Here, we identify a novel mechanism ofcarcinogenesis, whereby oncogenic Ras signalingenhances alternative splicing-mediated inactivationof the KLF6 tumor suppressor in hepatocellularcarcinomas. These Ras-dependent splice forms areshown to abrogate KLF6-mediated growth suppression,and ectopic KLF6 splice variant expression canrestore a Ras-transformed phenotype.