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Comparative Kinetics and Distribution to Target Tissues of Organophosphates Using Physiologically- Based Pharmacokinetic Modeling (Paperback or Softback)
Language: English
Published by Biblioscholar 11/29/2012, 2012
ISBN 10: 1288368801 ISBN 13: 9781288368808
Paperback or Softback. Condition: New. Comparative Kinetics and Distribution to Target Tissues of Organophosphates Using Physiologically- Based Pharmacokinetic Modeling. Book.
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Condition: As New. Unread book in perfect condition.
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Comparative Kinetics and Distribution to Target Tissues of Organophosphates Using Physiologically- Based Pharmacokinetic Modeling
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 19.03
£ 11.98 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: New. In.
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Comparative Kinetics and Distribution to Target Tissues of Organophosphates Using Physiologically- Based Pharmacokinetic Modeling
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
Condition: New.
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Comparative Kinetics and Distribution to Target Tissues of Organophosphates Using Physiologically- Based Pharmacokinetic Modeling
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
Condition: As New. Unread book in perfect condition.
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Condition: New. KlappentextrnrnA physiologically - based pharmacokinetic model has been developed to examine the effects of organophosphates on the levels of acetylcholine in different tissues throughout the mammalian body. Many organophosphate-like chemical an.
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Comparative Kinetics and Distribution to Target Tissues of Organophosphates Using Physiologically- Based Pharmacokinetic Modeling
Language: English
Published by British Library, Historical Print Editions Nov 2012, 2012
ISBN 10: 1288368801 ISBN 13: 9781288368808
Taschenbuch. Condition: Neu. Neuware - A physiologically - based pharmacokinetic model has been developed to examine the effects of organophosphates on the levels of acetylcholine in different tissues throughout the mammalian body. Many organophosphate-like chemical and kinetic characteristics are tested without reference to a specific chemical. Characteristics include partition coefficients, metabolic constants, the inhibition coefficient, the aging rate, and the regeneration rate. Two separate exposure scenarios are tested and compared against a baseline. The baseline consists of a direct inhalation exposure. The first exposure scenario examines the effects of bronchial scrubbing (via inhalation) and the second scenario is a study of dermal exposures and compares the levels of ACh in the different tissues with those in the inhalation (baseline) tests. Organophosphates that are absorbed directly into the bronchial tissue exhibit little variation on the levels of ACh buildup in any of the tissue groups tested when compared to the inhalation exposures. No matter what the scrubbing coefficient used, or the combination of the parameters (partition coefficients, inhibition coefficient, aging rate, and regeneration rate) values, the change in ACh was minimal. The results showed different behavior between inhalation and dermal exposures. The dermal results suggest that an individual may have additional time to don protective equipment before the levels of ACh are high enough to render the person incapable of doing so.
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Comparative Kinetics and Distribution to Target Tissues of Organophosphates Using Physiologically- Based Pharmacokinetic Modeling
Language: English
Published by British Library, Historical Print Editions, 2012
ISBN 10: 1288368801 ISBN 13: 9781288368808
PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
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Comparative Kinetics and Distribution to Target Tissues of Organophosphates Using Physiologically- Based Pharmacokinetic Modeling
Language: English
Published by British Library, Historical Print Editions, 2012
ISBN 10: 1288368801 ISBN 13: 9781288368808
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Seller rating 5 out of 5 stars
£ 18.96
£ 4.16 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketPAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
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Condition: New. Print on Demand pp. 216.
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Condition: New. Print on Demand pp. 216.
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Condition: New. PRINT ON DEMAND pp. 216.
