U Leuschner (168 results)

24 x 16,5 cm Paperback. Condition: Gut. 132 S. Sehr guter Zustand, nur geringe Gebrauchsspuren, Besitzerstempel auf dem Vorsatzblatt, ohne Texteintragungen, Markierungen, etc. Zusammengestellt von Schwarzendrube, J. und Stremmel, W. Mit 70 teils farbigen Abbildungen und 32 Tabellen. Die primär biliäre Zirrhose kennzeichnet nur das zirrhotische Spätstadiuum einer chronischen, nicht eitrigen, nicht bakteriellen Cholangitis. Es ist eine seltene Erkrankung mit einer jährlichen Neuinfektionsrate von ca. 5:100.000 Personen. Meist sind Frauen jenseits des 40. Lebensjahr betroffen. Oft bleiben die Patienten jahrelang asymptomatisch, d.h. sie fühlen sich wohl ohne jeglichen Krankheitssymptome, können jedoch durch zufällig dokumentierte Leberwerterhöhungen der ALP und GGT auffallen. Erst später kommen ein quälender Juckreiz, Müdkigkeit, eine Vergrösserung der Leber oder extrahepatischen Symptome wie eine Schilddrüsenentzündung, oder rheumatoide Gelenksbeschwerden hinzu. Unbehandelt kann sich auch hier eine Leberzirrhose mit all ihren Folgen entwickeln. Typische Laborzeichen sind Erhöhungen der anitmitochondrialen Antikörper (AMA) in über 90% der Fälle, eine starke IgM erhöhung, Erhöhung der ALP, GGT und des Bilirubins. Eine ursächliche therapie ist nicht bekannt, jedoch beeinflußt Ursodeoxycholsärue den Krankheitsverlauf in den Frühstadien ( I - III) sehr günstig in einer Dosierung von 15 mg/kg Körpergewicht. Sollte es zur Ausbildung einer fortgeschrittenen Leberzirrhose kommen, so kann bei einem Bilirubinspiegel von ca. 5 mg % eine Lebertransplantation erwogen werden, da in diesem Stadium die Lebenserwartung doch deutlich eingeschränkt ist. Die primär sklerosierende Cholangitis ist ebenfalls eine seltenen Erkrankung mit einer jährlichen Neuinfektionsrate von 1-5:100.000 Personen. Hiervon sind vor allem Männer im Alter zwischen 30 und 50 Jahren betroffen. In mehr als als 70% der Fälle liegt gleichzeitie eine chronisch entzündliche Darmerkrankung (Colitis ulcerosa) vor. Im Frühstadium bleibt die oft Erkrankung unerkannt, da die Patienten keine Beschwerden haben, später kommen eine Gelbsucht und ein Juckreiz hinzu. Eine Leberzirrhose mit all ihren Folgen kann sich bei unbehandelten oder sehr spät diagnostizierten Patienten entwickeln. Laborchemisch ist die Erkrankung durch eine Erhöhung der ALP und GGT gekennzeichnet. Die Diagnostik der Wahl ist die endoskopisch retrograde Cholangiographie, die Gallenwegsspiegelung und Darstellung mit Kontrastmittel (ERC). Bei der Therapie haben sich die Ursodeoxycholsäure in einer Dosis von 15 mg/kg Körpergewicht und bei führenden Engstellen der großen Gallengänge wiederholte endoskopische Aufdehnungen (Dilatationen) der Gallengänge etabliert. Hierdurch werden Lebensverlängerungen und Verlängerung der Zeiten bis zu einer möglicherweise notwendigen Lebertransplantation erreicht. Zustand: leichte Gebrauchsspuren 3794513916 Sprache: de Gewicht in Gramm: 280.

Condition: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. Dust jacket in good condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,350grams, ISBN:0792387821.

Hardcover. Condition: New. ~ NEW Inside and Out! Clean & Crisp Pages. (E-mail for more info./pics).

Hardcover. Condition: As New. Leichte Kratzer / Abnutzungen / Druckstellen. Leber- und Gallekrankenheiten nehmen in Klinik und Praxis einen zentralen Platz ein. Deshalb ist die Kenntnis der neuesten Therapie-Fortschritte auf diesem Gebiet für Internisten unverzichtbar. Das erfolgreiche Therapie-Handbuch bietet eine ideale kompakt, praxisbezogen, mit gesicherten Therapie-Empfehlungen und genauen Therapie-Anwendungen. Die Neuauflage ist komplett überarbeitet und um neueste Erkenntnisse zur Interferon-Therapie, zur Behandlung der Hepatitiden sowie um die Ständigen Empfehlungen der Impfkommission (STIKO) erweitert.

Broschiert. Condition: Gut. 36 Seiten gutes und sauberes Exemplar Sprache: Deutsch Gewicht in Gramm: 125.

Leinen. Condition: Neuwertig. Dust Jacket Condition: Sehr guter Umschlag. 31. Januar 1996, Kluwer Academic Publishers, Falk Symposium 84 Size: Ca 16x24 Cm. Eng.

Hardcover. Condition: Near Fine. Dust Jacket Condition: Good. 1402028938; Unread Pictorial board hardcover, light edge wear and spine fade on jacket, from closed Astra Zeneca company library. Lending record shows this book has never been borrowed. 276 pages, index, illustrated with charts, tables and diagrams. Proceedings of the Falk Symposium 141, XVIII International Bile Acid Meeting, held in Stockholm, June 2004. Many novel results of bile acid research are presented at these meetings. Contents as new clean, tight and bright. Book.

Cloth. Condition: Like New. Dust Jacket Condition: Very Good. Type: Book Pregnancy represents an allograft in so far that half of the antigens are foreign to the mother. Therefore, a bidirectional interaction between the maternal and the fetal immune systems must exist, which could be disturbed by preexisting autoimmune liver diseases. Since nowadays autoimmune liver diseases are increasingly detected as early stage diseases due to modern diagnostic procedures, e.g. in women of childbearing age, and since the number of posttransplant pregnancies has become an issue due to improved survival, questions concerning pregnancy, autoimmune liver disease and treatment options with bile acids and/or immunosuppressants are of an ever-increasing interest. This book, the proceedings of a Falk Workshop held in Freiburg, Germany, on June 2, 2002, is certainly unable to give any definite answers to any of the hundreds of still remaining questions in this fascinating field, but hopefully it will help to stimulate and initiate cooperation among immunologists, bile acid researchers, gynaecologists and internists.N.B.D/J spine slightly faded with slight mark to base of d/j spine.80pp.

Cloth. Condition: Like New. Dust Jacket Condition: Like New. Type: Book On the occasion of the 80th birthday of Dr. Herbert Falk an international symposium was held in Freiburg, Germany, on 16-17 October 2004. The aim of the meeting was to look back, to assess progress made and to look forward speculating on the development of the field of gastroenterology and hepatology. The symposium was divided into four parts: oesophagus and stomach, liver, pancreaticobiliary tract, and small/large bowel. Internationally renowned speakers contributed to the symposium, many of them also contributed to this book. The organizers of the symposium hope that this volume will maintain the memory of a remarkable meeting in honour of an even more remarkable person. 329pp.

Condition: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

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Hardcover. Condition: Very Good. Dust Jacket Condition: Very Good. 1st Edition. Hardcover, xvi + 293 pages, NOT ex-library. Clean and bright throughout, with unmarked text, free of inscriptions and stamps; firmly bound. Dust jacket with a heavily sunned spine, else very good, untorn, clean, showing minor handling wear. Not an economy/Asian edition. -- Proceedings of Falk Symposium 129 dedicated to basic and clinical aspects of bile acid research with a focus on the role of bile acids in hepatobiliary and intestinal diseases. The latest findings are presented by the leading scientists and clinicians in the field. -- Contents: Adolf Windaus Prize Lecture: Enzymes & Genes of Bile Acid Synthesis; I: Regulation of Gene Expression by Bile Acids: 1 Homeostatic Control of Bile Acid Biosynthesis & Transport by Nuclear Receptors 2 Crosstalk Between Nuclear Receptor & Cytokine-Activated Pathways in the Regulation of Ntcp Gene Expression 3 Transactivation of the Human OATP8 Gene by the Farnesoid X Receptor/Bile Acid Receptor (FXR/BAR); II: Synthesis & Metabolism of Bile Acids: 4 Vitamin D Receptor as a Bile Acid Sensor 5 Molecular Mechanisms of Nuclear Receptor Regulation of Bile Acid Synthesis 6 Manipulating the Bile Acid Pool Regulates CYP7A1 by Changing FXR Activation 7 Role of Mitochondrial Cholesterol Transport in Bile Acid Biosynthesis 8 Regulation of Bile Acid Formation in the Human Liver; III: Transport of Bile Acids & Bile Secretion: 9 Mutations in the Sodium-Independent Bile Salt Uptake Transporter of Human Liver SLC21A6 10 Regulation of the Rat Organic Anion Transporting Polypeptide 4 (Oatp4) by Bile Acids 11 Function & Regulation of Expression of the Canalicular Bile Salt Export Pump 12 Function of BSEP 13 Sinusoidal Efflux of Bile Acids via Mrp3 (ABCC3) 14 Organ-Specific Regulation of Nuclear Hormone Receptors & Bile Salt Transport Proteins in Obstructive Cholestasis 15 Effects of Bile Salt Flux Variations on the Expression of Hepatic Bile Salt Transporters in vivo in Rodents 16 Cloning & Characterization of Rat Bile Salt Export Pump Promoter: Bile Acid Activation is Mediated via Farnesoid X Receptor/Bile Acid Receptor 17 Effect of Progressive Familial Intrahepatic Cholestasis Type 2 (PFIC-2) Mutations on Functioning of the Bile Salt Export Pump 18 Short-Term Regulation of Bile Secretion 19 Taurolithocholic Acid Impairs Bile Secretion by Phosphatidylinositol 3-Kinase- & Protein Kinase Ce-Dependent Mechanisms 20 Mouse Models of Intestinal Bile Acid Malabsorption 21 Characterization & Identification of the Intestinal Cholesterol Uptake System; IV: Bile Acids in Disease: 22 Acquired Alterations of Hepatobiliary Transport Systems in Human Cholestatic Liver Diseases: Potential Targets of Pharmacotherapy 23 Biliary Lipid Composition in Benign Recurrent Intrahepatic Cholestasis 24 Mutations in MDR3 in Adult Onset Cholangiopathy 25 MDR3 Gene Mutations & Cholesterol Cholelithiasis 26 Expression & Localization of Hepatocellular Transporters & Radixin in Primary Biliary Cirrhosis 27 Neonatal Liver Disease in Two Siblings Caused by a Failure to Racemize (25r)Trihydroxy-Cholestanoic Acid Due to a Gene Mutation in 2-Methylacyl-CoA Racemase: Effectiveness of Cholic Acid Therapy in Preventing Liver & Neurological Disease; V: Bile Acids in Therapy: 28 UDCA & TUDCA Ameliorate Hepatocyte Damage Caused by EtOH & Acetaldehyde by Different Mechanisms 29 Ursodeoxycholic Acid Therapy Affects the Cytokine Network & Plays an Immunomodulatory Role in Patients with Primary Sclerosing Cholangitis & Primary Biliary Cirrhosis 30 Dose Response of UDCA in the Treatment of Cholestatic Disorders 31 High Dose Ursodeoxycholic Acid in the Management of Primary Sclerosing Cholangitis 32 Intrahepatic Cholestasis of Pregnancy: Placebo Controlled Randomised Trial of Ursodeoxycholic Acid vs Dexamethasone on Maternal & Fetal Outcome & Metabolism 33 Ursodeoxycholic Acid in the Chemoprevention of Colon Cancer 34 Tauroursodeoxycholic Acid for the Treatment of Acute & Chronic Neurodegenerative Diseases; Index.

HardBack. Condition: Fine. Dust Jacket Condition: Fine. The book looks newbinding tight and square,contents clean and unmarked.

Condition: Used. pp. 96.

Condition: Used. pp. 96.

hardcover. Condition: Good. Connecting readers with great books since 1972! Used textbooks may not include companion materials such as access codes, etc. May have some wear or writing/highlighting. We ship orders daily and Customer Service is our top priority!

Condition: Used. pp. 96.

Falk Symposium 142. Book appears to be unused. Dustjacket protected by removable clear film. Used - Very Good. VG hardback in VG dustjacket Used - Very Good. VG hardback in VG dustjacket.

Condition: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Hardcover. Condition: Very Good.

Condition: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Condition: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Condition: New. Brand New Original US Edition. Customer service! Satisfaction Guaranteed.

Condition: New. pp. 412.

Hardcover. Condition: Good. Connecting readers with great books since 1972! Used textbooks may not include companion materials such as access codes, etc. May have some wear or writing/highlighting. We ship orders daily and Customer Service is our top priority!

Condition: New. pp. 412 Illus.

Condition: New. pp. 412.