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![Stock image for Predictive ADMET: Integrated Approaches in Drug Discovery and Development [Hardcover] Wang, Jianling and Urban, Laszlo for sale by RUSH HOUR BUSINESS](https://pictures.abebooks.com/isbn/9781118299920-uk-300.jpg)
hardcover. Condition: Very Good. Pages are clean with no markings.
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Predictive Toxicology In Drug Safety
Language: English
Published by Cambridge University Press, 2010
ISBN 10: 0521763649 ISBN 13: 9780521763646
Condition: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
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Predictive Toxicology In Drug Safety
Language: English
Published by Cambridge University Press, 2010
ISBN 10: 0521763649 ISBN 13: 9780521763646
Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
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Hardcover. Condition: Fine. Dust Jacket Condition: Fine. Urban Laszlo (illustrator). First Edition. Scarce first edition in Hungarian of Beckett's comic masterpiece, his first fictional work to appear in Hungarian translation. The translation is by Tandori Dezso with a 16pp introduction and footnotes by Mihalyi Gabor. There is an original Surrealist artwork on the dw by Urban Laszlo depicting a giant fly in a rocking chair. Yellow linen lettered in black, top edge stained orange. Minimal sunning to dw spine else that too is Fine.
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Cellular Mechanisms of Sensory Processing: The Somatosensory System (Nato ASI Subseries H:)
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 96.88
£ 11.98 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: New. In.
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Predictive Toxicology in Drug Safety
Language: English
Published by Cambridge University Press CUP, 2010
ISBN 10: 0521763649 ISBN 13: 9780521763646
Condition: Used. pp. 410.
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Hit and Lead Profiling: Identification and Optimization of Drug-like Molecules
Seller: Optimon Books, Gravesend, KENT, United Kingdom
Seller rating 5 out of 5 stars
Hardcover. Condition: Very Good. THERE ARE NO TARIFFS OR CUSTOMS DUTIES ON BOOKS. Hit and Lead Profiling: Identification and Optimization of Drug-like Molecules by Bernard Faller & Laszlo Urban eds.Includes inscription to 'Humphrey' by Laszlo UrbanMethods and Principles in Medicinal Chemistry, Vol. 43The only reference on current methods to generate pharmacokinetic and safety profiles of drug candidates, as well as how they must be balanced against one other for the best selection of candidates for further development. Following a brief introduction to the necessities of filtering and risk assessment of potential new drug molecules before actual drug development, the two equally important aspects of pharmacological (ADME) and safety (toxicity) profiling are covered in separate parts. The ADME section covers the profiling of basic physicochemical parameters, such as solubility and permeability, as well as more complex traits, such as the likelihood of drug-drug interactions, metabolic clearance and protein binding properties. The toxicology part addresses, among others, recent advances in early genetic toxicity testing, bioactivation screening, organ-specific toxicity assays for liver, heart, kidney and blood, as well as profiling for autoimmune reactions. By addressing both drug efficiency and drug safety, this modern practical reference shows readers how each individual aspect figures in shaping the key decisions on which the entire drug development process hinges. In short, this is a complete toolbox for assessing the risk/benefit ratio for any novel compound during the early drug development stages, using both in vitro and in silico methods. Both editors are based at one of the leading research-driven pharmaceutical companies, and the authors have been recruited from numerous other global players in the field. Invaluable know-how for every medicinal chemist and drug developer.In good condition with clean pages inside. Front free endpaper is inscribed with dedication in blue ink. Copyright Âİ Wiley-VCH.
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Predictive Toxicology in Drug Safety
Language: English
Published by Cambridge University Press, 2010
ISBN 10: 0521763649 ISBN 13: 9780521763646
Condition: Used. pp. 410.
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Predictive Toxicology in Drug Safety
Language: English
Published by Cambridge University Press, 2010
ISBN 10: 0521763649 ISBN 13: 9780521763646
Condition: Used. pp. 410.
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Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
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Condition: As New. Unread book in perfect condition.
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Predictive ADMET: Integrated Approaches in Drug Discovery and Development
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 125.65
£ 11.98 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: New. In.
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Predictive Admet : Integrated Approaches in Drug Discovery and Development
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
Condition: New.
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Antitargets and Drug Safety (Methods & Principles in Medicinal Chemistry)
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 130.17
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Ships from United Kingdom to U.S.A.Quantity: Over 20 available
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Predictive Admet : Integrated Approaches in Drug Discovery and Development
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
Condition: As New. Unread book in perfect condition.
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Condition: New.
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Predictive Toxicology in Drug Safety
Language: English
Published by Cambridge University Press, 2010
ISBN 10: 0521763649 ISBN 13: 9780521763646
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 132.73
£ 11.98 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: New. In.
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Cellular Mechanisms of Sensory Processing: The Somatosensory System (Nato Asi Series (Closed) / Nato Asi Subseries H: (Closed))
Language: English
Published by Springer Berlin Heidelberg, 2012
ISBN 10: 3642787649 ISBN 13: 9783642787645
Paperback. Condition: Brand New. reprint edition. 513 pages. 9.25x6.10x1.30 inches. In Stock.
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Antitargets and Drug Safety
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
£ 130.16
£ 15 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: New.
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Condition: As New. Unread book in perfect condition.
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Cellular Mechanisms of Sensory Processing : The Somatosensory System
Language: English
Published by Springer Berlin Heidelberg, 2011
ISBN 10: 3642787649 ISBN 13: 9783642787645
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The research field of somatosensory processing in mammals has experienced revolutionary changes in recent years. Accumulation of basic and clinical data has greatly accelerated, and new phenomena have emerged. With the aid of new, refined methods, molecular and cellular changes have been described, underlying the signal transduction-transmission between the internal/external environment and the central nervous system have been described. The discovery of the interaction between the nervous and the immune system has, for example changed our view on the development of inflammatory diseases, while the cloning of genes encoding different trophic factors has boosted studies revealing profound changes in the regeneration of neurons, and induction of changes in phenotype. The study of the pre-and postsynaptic modulation of transmitter release, and the examination of the combined effects of amino acid and peptide transmitters has become recently possible by using cultured cell lines and in vitro techniques. Although it is in embryonic state, computational properties of single DRG cells under normal and pathological conditions are being investigated. Results soon or later will have a great impact on pain research and consequently ultimately in clinical pain management. This brief introduction indicates how our knowledge of the somatosensory system has increased dramatically recently. However, many investigators cultivate only a very specific field in the growing area of somatosensory research and find it difficult to integrate a more universal knowledge of their work.
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Predictive Toxicology in Drug Safety
Language: English
Published by Cambridge University Press, 2010
ISBN 10: 0521763649 ISBN 13: 9780521763646
Hardcover. Condition: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
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Predictive ADMET
Language: English
Published by John Wiley and Sons Inc, US, 2014
ISBN 10: 1118299922 ISBN 13: 9781118299920
Seller: Rarewaves.com USA, London, LONDO, United Kingdom
Seller rating 5 out of 5 stars
Hardback. Condition: New. This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and present appropriate recommendations to move drug discovery programs forward. The book introduces the current clinical practice for drug discovery and development along with the impact on early risk assessment; consolidates the tools and models to intelligently integrate existing in silico, in vitro and in vivo ADMET data; and demonstrates successful cases and lessons learned from real drug discovery and development. In short, it is a book aimed to provide a practical road map for drug discovery and development scientists to generate efficacious and safe drugs for unmet medical needs.
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Condition: New. pp. 336.
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Hardcover. Condition: New.
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Antitargets and Drug Safety
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
£ 144.02
£ 15 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: As New. Unread book in perfect condition.
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Condition: New. pp. 616.
