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  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

    • Hardcover

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    Hardcover. Condition: Good. Good+. Hardcover, xvii + 145 pages. An uncirculated university library withdrawal, stamped accordingly. An external stamp on upper and lower page edges, internal library markings on pastedowns & prelims. Pages are clean, bright, with unmarked text and firm binding. Boards show a crease to the upper rear corner, short creases to spine ends, small indentations. Issued without a dust jacket. -- In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL-2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential therapeutic benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism. -- Contents: Homeostatic Functions of BCL-2 Proteins Beyond Apoptosis [Abstract; Introduction; Mitochondrial Energy Metabolism; Autophagy; Protein Quality Control and the Unfolded Protein Response; Physiologic Roles for BCL-2 Family Proteins in Cell Cycle Checkpoints, Differentiation and DNA Damage Response]; Alternative Functions of the BCL-2 Protein Family at the Endoplasmic Reticulum [Abstract; Introduction; BCL-2 Protein Family and the Unfolded Protein Response; Chronic ER Stress and BH3-Only Proteins; BCL-2 Protein Family and the Calcium Rheostat; Autophagy and the BCL-2 Protein Family of Proteins]; BH3-Only Proteins and Their Effects on Cancer [Abstract; Introduction; Categories of BCL-2 Family Proteins and Their Apoptotic Functions; Regulation of Various BH3-Only Proteins and Cell Stress Sensing; BH3-Only Proteins and Cancer Development; BH3-Only Proteins and Chemotherapy Response and Resistance; BH3-Only Mimetic Drugs]; Endoplasmic Reticulum Stress and BCL-2 Family Members [Abstract; Introduction; UPR: The Good and the Evil Side; UPR and BCL-2 Family Members; Autophagy, UPR and BCL-2 Family Members]; Targeting Survival Pathways in Lymphoma [Abstract; Introduction; Pharmacologic Modulation of BCL-2 Proteins and Apoptosis; BCL-2 Proteins and Non-Apoptotic Cell Death]; Interplay Between BCL-2 Family Proteins and Mitochondrial Morphology in the Regulation of Apoptosis [Abstract; Introduction; BCL-2 Family; Mitochondrial Shape and Apoptosis]; Noncanonical Functions of BCL-2 Proteins in the Nervous System [Abstract; Introduction; Extending the Traditional View of BCL-2 Family Proteins; Challenging the Traditional BCL-2 Family Model; BCL-2 Family Proteins in the Nervous System; When Anti-Death BCL-2 Proteins Become Pro-Death; When Pro-Death BCL-2 Proteins Protect Neurons; Protection Predicts New Functions with a Seizure; BCL-2 Family Proteins Regulate Synaptic Activity; Mitochondrial Dynamics in Neuronal Function]; Mitochondria on Guard: Role of Mitochondrial Fusion and Fission in the Regulation of Apoptosis [Abstract; Introduction; Regulation of Mitochondrial Fusion and Fission; Mitochondrial Network Dynamics and Cell Homeostasis; Role of Mitochondrial Dynamics in Cell Death; Mechanism of the OMM Permeabilization: A Vital Role for Mitochondrial Fusion and Fission?; Emerging Evidence for the Role of BCL-2 Family Proteins in the Regulation of Mitochondrial Network Dynamics in Healthy Cells].

  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

    • Hardcover

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    Condition: New. pp. xvii + 145.

  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

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    Condition: New. pp. xvii + 145 Illus.

  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

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    Condition: New. pp. xvii + 145.

  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

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  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

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  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

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  • Language: English

    Published by Bentham Science Publishers, 2018

    1608055752 / 9781608055753

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  • Language: English

    Published by Bentham Science Publishers, 2018

    1608055752 / 9781608055753

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  • Language: English

    Published by SP SPRINGER, 2010

    1441967052 / 9781441967053

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    Condition: New. Brand New! Fast Delivery This is an International Edition and ship within 24-48 hours. Deliver by FedEx and Dhl, & Aramex, UPS, & USPS and we do accept APO and PO BOX Addresses. Order can be delivered worldwide within 6-10 days and we do have flat rate for up to 2LB. Extra shipping charges will be requested if the Book weight is more than 5 LB. This Item May be shipped from India, United states & United Kingdom. Depending on your location and availability.

  • Language: English

    Published by Bentham Science Publishers, 2018

    1608055752 / 9781608055753

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  • Language: English

    Published by Bentham Science Publishers, 2018

    1608055752 / 9781608055753

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  • Language: English

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  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

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  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

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  • Language: English

    Published by BENTHAM SCIENCE PUB, 2018

    1608055752 / 9781608055753

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  • Language: English

    Published by Springer New York, 2010

    1441967052 / 9781441967053

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    Condition: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL¿2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism.

  • Language: English

    Published by Amazon Digital Services LLC - Kdp, 2018

    1608055752 / 9781608055753

    • Softcover

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    Taschenbuch. Condition: Neu. Neuware.

  • Language: English

    Published by Springer, 2014

    1489985352 / 9781489985354

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    Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL 2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism.

  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

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    Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL 2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism.

  • Language: English

    Published by Springer, 2014

    1489985352 / 9781489985354

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    Condition: New. pp. 164.

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    Language: English

    Published by Springer, 2014

    1489985352 / 9781489985354

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    Taschenbuch. Condition: Neu. BCL¿2 Protein Family | Essential Regulators of Cell Death | Claudio Hetz | Taschenbuch | xvii | Englisch | 2014 | Springer | EAN 9781489985354 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

  • Language: English

    Published by Springer, 2014

    1489985352 / 9781489985354

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    Paperback. Condition: Brand New. 162 pages. 9.25x6.10x0.37 inches. In Stock.

  • Language: English

    Published by Springer, 2014

    1489985352 / 9781489985354

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  • Language: English

    Published by Springer, 2010

    1441967052 / 9781441967053

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  • Language: English

    Published by Springer, 2014

    1489985352 / 9781489985354

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  • Language: English

    Published by Bentham Science Publishers, 2018

    1608055752 / 9781608055753

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  • Language: English

    Published by Springer New York Nov 2014, 2014

    1489985352 / 9781489985354

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    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL 2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism. 164 pp. Englisch.

  • Language: English

    Published by Springer New York Jul 2010, 2010

    1441967052 / 9781441967053

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    Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL 2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism. 164 pp. Englisch.

  • Language: English

    Published by Springer New York, 2010

    1441967052 / 9781441967053

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    Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Focusses on the potential therapeutic benefits of targeting apoptosis pathways in the context of human diseaseProvides an overview of the emerging roles of BCL-2 family members in different physiological and pathological conditionsAlternative functions of B.