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Condition: As New. Unread book in perfect condition.
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Condition: New.
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paperback. Condition: New. Open Books is a nonprofit social venture that provides literacy experiences for thousands of readers each year through inspiring programs and creative capitalization of books.
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Soft cover. Condition: Good. 1st Edition. Oversized paperback, xxiv + 450 pages, NOT ex-library. Weight over 1kg. 2 first pages not bound in (manufacturing fault); a corner crease on the front cover, gentle rubbing to cover edges, external shelfwear. Interior is clean and bright with unmarked text, free of inscriptions and stamps, firmly bound. Spine remains free of creasing. Good+ condition. -- This edited volume provides a comprehensive treatment of pan-genomics, the study of the entire gene repertoire of a species or taxonomic group rather than a single reference genome. The field emerged from the recognition that no single genome can capture the full genetic diversity within a species, and that genes present in some strains or individuals but absent from the reference sequence - the so-called dispensable or accessory genome - often carry critical information about adaptation, virulence and drug resistance. The contents are organised around three axes indicated by the title. Opening chapters address the conceptual foundations and bioinformatics approaches applied in pan-genomic analysis, including the computational tools required to construct, annotate and query pan-genomes from large-scale sequencing data. A substantial portion of the book focuses on bacterial comparative genomics, where pan-genomic methods have had their most mature application, leveraging these approaches for the development of precise diagnostics, vaccines and drug targets. The text presents twelve specific case studies covering a diverse range of organisms, including human pathogens (Corynebacterium), veterinary and plant pathogens, and model bacteria. The coverage extends beyond microbiology into plant genomics, human genetics (including pan-cancer analysis), and the pan-genomics of fungi, algae and viruses. This reflects the broadening scope of pan-genomic methods as sequencing costs have fallen and long-read technologies such as PacBio and Oxford Nanopore have improved the resolution of complex and repetitive genomic regions. Chapters address the transition from linear reference genomes to graph-based representations capable of encoding structural variation, copy number differences and presence-absence variation across populations. The computational challenges receive sustained attention, including the storage and processing of datasets that can reach petabyte scale, the development of efficient algorithms for sequence alignment against graph genomes, and the functional annotation of variable genes absent from reference sequences. Final sections explore the emerging integration of pan-genomics with other 'omics' layers, such as pan-transcriptomics, pan-proteomics and pan-metabolomics, to provide a multi-dimensional view of species.
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Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
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Progress and Challenges in Precision Medicine
Language: English
Published by Academic Press 2017-01-09, 2017
ISBN 10: 0128094117 ISBN 13: 9780128094112
£ 91.56
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Add to basketPaperback. Condition: New.
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Condition: New.
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Condition: New. pp. 384.
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Hardcover. Condition: Brand New. 1st edition. 625 pages. 9.25x7.50x1.75 inches. In Stock.
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Condition: As New. Unread book in perfect condition.
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Condition: As New. Unread book in perfect condition.
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Condition: New. pp. 384.
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Omics Technologies and Bio-engineering: Volume 2: Towards Improving Quality of Life
Language: English
Published by Elsevier Science Publishing Co Inc, 2018
ISBN 10: 0128158700 ISBN 13: 9780128158708
Seller: THE SAINT BOOKSTORE, Southport, United Kingdom
Seller rating 5 out of 5 stars
£ 105.49
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Add to basketHardback. Condition: New. New copy - Usually dispatched within 4 working days.
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Progress and Challenges in Precision Medicine
Language: English
Published by Elsevier Science Publishing Co Inc, 2017
ISBN 10: 0128094117 ISBN 13: 9780128094112
Seller: THE SAINT BOOKSTORE, Southport, United Kingdom
Seller rating 5 out of 5 stars
£ 111.65
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Omics Technologies and Bio-engineering: Volume 2: Towards Improving Quality of Life
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 117.61
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Condition: New.
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Omics Technologies and Bio-Engineering : Towards Improving Quality of Life: Microbial, Plant, Environmental and Industrial Technologies
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
£ 117.60
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Condition: New.
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Progress and Challenges in Precision Medicine
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 125.69
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Paperback. Condition: Brand New. 270 pages. 11.00x8.75x0.50 inches. In Stock.
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Paperback. Condition: Brand New. 400 pages. 9.25x7.50x1.06 inches. In Stock.
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Progress and Challenges in Precision Medicine
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
£ 125.68
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Condition: New. pp. 384.
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Single-Cell Omics: Volume 2: Technological Advances and Applications
Language: English
Published by Elsevier Science Publishing Co Inc, 2019
ISBN 10: 012817532X ISBN 13: 9780128175323
Seller: THE SAINT BOOKSTORE, Southport, United Kingdom
Seller rating 5 out of 5 stars
£ 122.68
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Add to basketPaperback / softback. Condition: New. New copy - Usually dispatched within 4 working days.
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Condition: New. pp. 544.
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Condition: New.
