Allimuthu Dharmaraja (21 results)

Author: 
Refine with Advanced Search

Refine your search

  • Books (21)

  • New (21)

to

Custom price range (£)

to

  • Language: English

    Published by LAP LAMBERT Academic Publishing, 2017

    3330069155 / 9783330069152

    • Softcover

    Seller: Revaluation Books, Exeter, United KingdomRevaluation Books

    5-star seller
    Contact seller

    Condition: New

    £ 52.93

    £ 10.00 shipping 
    Ships from United Kingdom to U.S.A.

    Quantity: 1 available

    Paperback. Condition: Brand New. 64 pages. 8.66x5.91x0.15 inches. In Stock.

  • Language: English

    Published by LAP LAMBERT Academic Publishing, 2017

    3330069155 / 9783330069152

    • Softcover

    Seller: preigu, Osnabrück, Germanypreigu

    5-star seller
    Contact seller

    Condition: New

    £ 29.02

    £ 59.23 shipping 
    Ships from Germany to U.S.A.

    Quantity: 5 available

    Taschenbuch. Condition: Neu. Reactive Oxygen Species (ROS) Based Therapeutics | Role of ROS in therapeutics and drug resistance in cancer and bacteria | Dharmaraja Allimuthu | Taschenbuch | 64 S. | Englisch | 2017 | LAP LAMBERT Academic Publishing | EAN 9783330069152 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

  • Language: English

    Published by LAP LAMBERT Academic Publishing Apr 2017, 2017

    3330069155 / 9783330069152

    • Softcover
    • Print on Demand

    Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 19.46 shipping 
    Ships from Germany to U.S.A.

    Quantity: 2 available

    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -ROS a 'double edged sword': Evading persistent drug resistance in cancer and bacteria is quintessential to restore health in humans, and impels intervention strategies. A distinct property of the cancer phenotype is enhanced glucose metabolism and oxidative stress. Reactive oxygen species (ROS) are metabolic byproducts of aerobic respiration and are responsible for maintaining redox homeostasis in cells. Redox balance and oxidative stress are orchestrated by antioxidant enzymes, reduced thiols and NADP(H) cofactors, which is critical for cancer cells survival and progression. Similarly, Escherichia coli (E. coli) and life-threatening infectious pathogens such as Staphylococcus aureus (SA) and Mycobacterium tuberculosis (Mtb) are appreciably sensitive to changes in the intracellular oxidative environment. Thus, small molecules that modulate antioxidant levels and/or enhance intracellular ROS could disturb the cellular oxidative environment and induce cell death, and hence could serve as novel therapeutics. Presented here are a collection of approaches that involve ROS modulation in cells as a strategy to target cancer and bacteria. 64 pp. Englisch.…

  • Language: Spanish

    Published by Ediciones Nuestro Conocimiento Feb 2024, 2024

    6207135571 / 9786207135578

    • Softcover
    • Print on Demand

    Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 19.46 shipping 
    Ships from Germany to U.S.A.

    Quantity: 2 available

    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 72 pp. Spanisch.

  • Language: English

    Published by LAP LAMBERT Academic Publishing, 2017

    3330069155 / 9783330069152

    • Softcover
    • Print on Demand

    Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

    5-star seller
    Contact seller

    Condition: New

    £ 36.33

    £ 29.62 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - ROS a 'double edged sword': Evading persistent drug resistance in cancer and bacteria is quintessential to restore health in humans, and impels intervention strategies. A distinct property of the cancer phenotype is enhanced glucose metabolism and oxidative stress. Reactive oxygen species (ROS) are metabolic byproducts of aerobic respiration and are responsible for maintaining redox homeostasis in cells. Redox balance and oxidative stress are orchestrated by antioxidant enzymes, reduced thiols and NADP(H) cofactors, which is critical for cancer cells survival and progression. Similarly, Escherichia coli (E. coli) and life-threatening infectious pathogens such as Staphylococcus aureus (SA) and Mycobacterium tuberculosis (Mtb) are appreciably sensitive to changes in the intracellular oxidative environment. Thus, small molecules that modulate antioxidant levels and/or enhance intracellular ROS could disturb the cellular oxidative environment and induce cell death, and hence could serve as novel therapeutics. Presented here are a collection of approaches that involve ROS modulation in cells as a strategy to target cancer and bacteria.…

  • Language: English

    Published by LAP LAMBERT Academic Publishing, 2017

    3330069155 / 9783330069152

    • Softcover
    • Print on Demand

    Seller: moluna, Greven, Germanymoluna

    5-star seller
    Contact seller

    Condition: New

    £ 27.26

    £ 41.45 shipping 
    Ships from Germany to U.S.A.

    Quantity: Over 20 available

    Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Allimuthu DharmarajaDharmaraja Allimuthu obtained his B.Sc in chemistry from Government Arts College-Salem in 2003 and M.Sc in 2005 from Bharathidasan University Trichy, Tamilnadu India. Dharmaraja graduated his Ph. D from Indian Ins. …

  • Language: French

    Published by Editions Notre Savoir Feb 2024, 2024

    6207135598 / 9786207135592

    • Softcover
    • Print on Demand

    Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 19.46 shipping 
    Ships from Germany to U.S.A.

    Quantity: 2 available

    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 72 pp. Französisch.

  • Language: Spanish

    Published by Ediciones Nuestro Conocimiento, 2024

    6207135571 / 9786207135578

    • Softcover
    • Print on Demand

    Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

    5-star seller
    Contact seller

    Condition: New

    £ 36.33

    £ 29.62 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Las ERO, un 'arma de doble filo Evitar la resistencia persistente a los fármacos en el cáncer y las bacterias es esencial para restablecer la salud en los seres humanos, e impulsa estrategias de intervención. Una propiedad distintiva del fenotipo del cáncer es el aumento del metabolismo de la glucosa y del estrés oxidativo. Las especies reactivas de oxígeno (ROS) son subproductos metabólicos de la respiración aeróbica y responsables del mantenimiento de la homeostasis redox en las células. El equilibrio redox y el estrés oxidativo están orquestados por enzimas antioxidantes, tioles reducidos y cofactores NADP(H), lo que es crítico para la supervivencia y progresión de las células cancerosas. Del mismo modo, Escherichia coli (E. coli) y patógenos infecciosos potencialmente mortales como Staphylococcus aureus (SA) y Mycobacterium tuberculosis (Mtb) son sensiblemente sensibles a los cambios en el entorno oxidativo intracelular. Así pues, las pequeñas moléculas que modulan los niveles de antioxidantes y/o potencian las ERO intracelulares podrían alterar el entorno oxidativo celular e inducir la muerte celular, por lo que podrían servir como nuevas terapias. Aquí se presenta una colección de enfoques que implican la modulación de ROS en las células como estrategia para combatir el cáncer y las bacterias.…

  • Language: English

    Published by LAP LAMBERT Academic Publishing Apr 2017, 2017

    3330069155 / 9783330069152

    • Softcover
    • Print on Demand

    Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 50.77 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -ROS a 'double edged sword': Evading persistent drug resistance in cancer and bacteria is quintessential to restore health in humans, and impels intervention strategies. A distinct property of the cancer phenotype is enhanced glucose metabolism and oxidative stress. Reactive oxygen species (ROS) are metabolic byproducts of aerobic respiration and are responsible for maintaining redox homeostasis in cells. Redox balance and oxidative stress are orchestrated by antioxidant enzymes, reduced thiols and NADP(H) cofactors, which is critical for cancer cells survival and progression. Similarly, Escherichia coli (E. coli) and life-threatening infectious pathogens such as Staphylococcus aureus (SA) and Mycobacterium tuberculosis (Mtb) are appreciably sensitive to changes in the intracellular oxidative environment. Thus, small molecules that modulate antioxidant levels and/or enhance intracellular ROS could disturb the cellular oxidative environment and induce cell death, and hence could serve as novel therapeutics. Presented here are a collection of approaches that involve ROS modulation in cells as a strategy to target cancer and bacteria.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 64 pp. Englisch.…

  • Language: French

    Published by Editions Notre Savoir, 2024

    6207135598 / 9786207135592

    • Softcover
    • Print on Demand

    Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

    5-star seller
    Contact seller

    Condition: New

    £ 36.33

    £ 29.62 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Les ROS, une 'épée à double tranchant' : Éviter la résistance persistante aux médicaments dans le cancer et les bactéries est essentiel pour restaurer la santé chez l'homme et implique des stratégies d'intervention. Une propriété distincte du phénotype du cancer est l'augmentation du métabolisme du glucose et du stress oxydatif. Les espèces réactives de l'oxygène (ROS) sont des sous-produits métaboliques de la respiration aérobie et sont responsables du maintien de l'homéostasie redox dans les cellules. L'équilibre redox et le stress oxydatif sont orchestrés par les enzymes antioxydantes, les thiols réduits et les cofacteurs NADP(H), ce qui est essentiel pour la survie et la progression des cellules cancéreuses. De même, Escherichia coli (E. coli) et les pathogènes infectieux potentiellement mortels tels que Staphylococcus aureus (SA) et Mycobacterium tuberculosis (Mtb) sont très sensibles aux changements de l'environnement oxydatif intracellulaire. Ainsi, les petites molécules qui modulent les niveaux d'antioxydants et/ou augmentent les ROS intracellulaires pourraient perturber l'environnement oxydatif cellulaire et induire la mort des cellules, et donc servir de nouvelles thérapeutiques. Nous présentons ici une série d'approches qui impliquent la modulation des ROS dans les cellules comme stratégie pour cibler le cancer et les bactéries.…

  • Language: Spanish

    Published by Ediciones Nuestro Conocimiento Feb 2024, 2024

    6207135571 / 9786207135578

    • Softcover
    • Print on Demand

    Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 50.77 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Las ERO, un 'arma de doble filo Evitar la resistencia persistente a los fármacos en el cáncer y las bacterias es esencial para restablecer la salud en los seres humanos, e impulsa estrategias de intervención. Una propiedad distintiva del fenotipo del cáncer es el aumento del metabolismo de la glucosa y del estrés oxidativo. Las especies reactivas de oxígeno (ROS) son subproductos metabólicos de la respiración aeróbica y responsables del mantenimiento de la homeostasis redox en las células. El equilibrio redox y el estrés oxidativo están orquestados por enzimas antioxidantes, tioles reducidos y cofactores NADP(H), lo que es crítico para la supervivencia y progresión de las células cancerosas. Del mismo modo, Escherichia coli (E. coli) y patógenos infecciosos potencialmente mortales como Staphylococcus aureus (SA) y Mycobacterium tuberculosis (Mtb) son sensiblemente sensibles a los cambios en el entorno oxidativo intracelular. Así pues, las pequeñas moléculas que modulan los niveles de antioxidantes y/o potencian las ERO intracelulares podrían alterar el entorno oxidativo celular e inducir la muerte celular, por lo que podrían servir como nuevas terapias. Aquí se presenta una colección de enfoques que implican la modulación de ROS en las células como estrategia para combatir el cáncer y las bacterias.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 72 pp. Spanisch.…

  • Language: Portuguese

    Published by Edições Nosso Conhecimento Feb 2024, 2024

    620713561X / 9786207135615

    • Softcover
    • Print on Demand

    Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 19.46 shipping 
    Ships from Germany to U.S.A.

    Quantity: 2 available

    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 72 pp. Portugiesisch.

  • Language: German

    Published by Verlag Unser Wissen Feb 2024, 2024

    6207135547 / 9786207135547

    • Softcover
    • Print on Demand

    Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 19.46 shipping 
    Ships from Germany to U.S.A.

    Quantity: 2 available

    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 72 pp. Deutsch.

  • Language: Italian

    Published by Edizioni Sapienza Feb 2024, 2024

    6207135601 / 9786207135608

    • Softcover
    • Print on Demand

    Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 19.46 shipping 
    Ships from Germany to U.S.A.

    Quantity: 2 available

    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 72 pp. Italienisch.

  • Language: French

    Published by Editions Notre Savoir Feb 2024, 2024

    6207135598 / 9786207135592

    • Softcover
    • Print on Demand

    Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 50.77 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Les ROS, une 'épée à double tranchant' : Éviter la résistance persistante aux médicaments dans le cancer et les bactéries est essentiel pour restaurer la santé chez l'homme et implique des stratégies d'intervention. Une propriété distincte du phénotype du cancer est l'augmentation du métabolisme du glucose et du stress oxydatif. Les espèces réactives de l'oxygène (ROS) sont des sous-produits métaboliques de la respiration aérobie et sont responsables du maintien de l'homéostasie redox dans les cellules. L'équilibre redox et le stress oxydatif sont orchestrés par les enzymes antioxydantes, les thiols réduits et les cofacteurs NADP(H), ce qui est essentiel pour la survie et la progression des cellules cancéreuses. De même, Escherichia coli (E. coli) et les pathogènes infectieux potentiellement mortels tels que Staphylococcus aureus (SA) et Mycobacterium tuberculosis (Mtb) sont très sensibles aux changements de l'environnement oxydatif intracellulaire. Ainsi, les petites molécules qui modulent les niveaux d'antioxydants et/ou augmentent les ROS intracellulaires pourraient perturber l'environnement oxydatif cellulaire et induire la mort des cellules, et donc servir de nouvelles thérapeutiques. Nous présentons ici une série d'approches qui impliquent la modulation des ROS dans les cellules comme stratégie pour cibler le cancer et les bactéries.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 72 pp. Französisch.…

  • Language: German

    Published by Verlag Unser Wissen, 2024

    6207135547 / 9786207135547

    • Softcover
    • Print on Demand

    Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 29.62 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - ROS ein 'zweischneidiges Schwert': Die Umgehung der hartnäckigen Arzneimittelresistenz bei Krebs und Bakterien ist für die Wiederherstellung der Gesundheit des Menschen von entscheidender Bedeutung und gibt den Anstoß für Interventionsstrategien. Eine besondere Eigenschaft des Krebsphänotyps ist ein erhöhter Glukosestoffwechsel und oxidativer Stress. Reaktive Sauerstoffspezies (ROS) sind metabolische Nebenprodukte der aeroben Atmung und für die Aufrechterhaltung der Redox-Homöostase in Zellen verantwortlich. Das Redox-Gleichgewicht und der oxidative Stress werden durch antioxidative Enzyme, reduzierte Thiole und NADP(H)-Kofaktoren gesteuert, was für das Überleben und Fortschreiten von Krebszellen entscheidend ist. Auch Escherichia coli (E. coli) und lebensbedrohliche Infektionserreger wie Staphylococcus aureus (SA) und Mycobacterium tuberculosis (Mtb) reagieren sehr empfindlich auf Veränderungen des intrazellulären oxidativen Milieus. Daher könnten kleine Moleküle, die den Gehalt an Antioxidantien modulieren und/oder die intrazelluläre ROS erhöhen, das zelluläre oxidative Milieu stören und den Zelltod auslösen und somit als neuartige Therapeutika dienen. Hier wird eine Reihe von Ansätzen vorgestellt, bei denen die ROS-Modulation in Zellen als Strategie zur Bekämpfung von Krebs und Bakterien eingesetzt wird.…

  • Language: Italian

    Published by Edizioni Sapienza, 2024

    6207135601 / 9786207135608

    • Softcover
    • Print on Demand

    Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

    5-star seller
    Contact seller

    Condition: New

    £ 36.33

    £ 29.62 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - I ROS sono una 'spada a doppio taglio': Evitare la persistente resistenza ai farmaci nel cancro e nei batteri è fondamentale per ripristinare la salute negli esseri umani e spinge le strategie di intervento. Una proprietà distinta del fenotipo del cancro è l'aumento del metabolismo del glucosio e dello stress ossidativo. Le specie reattive dell'ossigeno (ROS) sono sottoprodotti metabolici della respirazione aerobica e sono responsabili del mantenimento dell'omeostasi redox nelle cellule. L'equilibrio redox e lo stress ossidativo sono orchestrati da enzimi antiossidanti, tioli ridotti e cofattori NADP(H), il che è fondamentale per la sopravvivenza e la progressione delle cellule tumorali. Allo stesso modo, l'Escherichia coli (E. coli) e i patogeni infettivi pericolosi per la vita come lo Staphylococcus aureus (SA) e il Mycobacterium tuberculosis (Mtb) sono sensibilmente sensibili ai cambiamenti dell'ambiente ossidativo intracellulare. Pertanto, piccole molecole che modulano i livelli di antiossidanti e/o aumentano i ROS intracellulari potrebbero disturbare l'ambiente ossidativo cellulare e indurre la morte cellulare, e quindi potrebbero servire come nuovi farmaci. Qui viene presentata una serie di approcci che prevedono la modulazione dei ROS nelle cellule come strategia per colpire il cancro e i batteri. …

  • Language: Portuguese

    Published by Edições Nosso Conhecimento, 2024

    620713561X / 9786207135615

    • Softcover
    • Print on Demand

    Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

    5-star seller
    Contact seller

    Condition: New

    £ 36.33

    £ 29.62 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Os ERO são uma 'faca de dois gumes': Evitar a resistência persistente aos medicamentos no cancro e nas bactérias é essencial para restabelecer a saúde nos seres humanos e impulsiona estratégias de intervenção. Uma propriedade distinta do fenótipo do cancro é o aumento do metabolismo da glicose e do stress oxidativo. As espécies reactivas de oxigénio (ROS) são subprodutos metabólicos da respiração aeróbica e são responsáveis pela manutenção da homeostase redox nas células. O equilíbrio redox e o stress oxidativo são orquestrados por enzimas antioxidantes, tióis reduzidos e cofactores NADP(H), o que é fundamental para a sobrevivência e a progressão das células cancerosas. Do mesmo modo, a Escherichia coli (E. coli) e os agentes patogénicos infecciosos potencialmente mortais, como o Staphylococcus aureus (SA) e o Mycobacterium tuberculosis (Mtb), são consideravelmente sensíveis a alterações do ambiente oxidativo intracelular. Assim, as pequenas moléculas que modulam os níveis de antioxidantes e/ou aumentam as ERO intracelulares podem perturbar o ambiente oxidativo celular e induzir a morte celular, pelo que podem servir como novas terapêuticas. Apresenta-se aqui um conjunto de abordagens que envolvem a modulação das ROS nas células como estratégia para combater o cancro e as bactérias.…

  • Language: Portuguese

    Published by Edições Nosso Conhecimento Feb 2024, 2024

    620713561X / 9786207135615

    • Softcover
    • Print on Demand

    Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 50.77 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Os ERO são uma 'faca de dois gumes': Evitar a resistência persistente aos medicamentos no cancro e nas bactérias é essencial para restabelecer a saúde nos seres humanos e impulsiona estratégias de intervenção. Uma propriedade distinta do fenótipo do cancro é o aumento do metabolismo da glicose e do stress oxidativo. As espécies reactivas de oxigénio (ROS) são subprodutos metabólicos da respiração aeróbica e são responsáveis pela manutenção da homeostase redox nas células. O equilíbrio redox e o stress oxidativo são orquestrados por enzimas antioxidantes, tióis reduzidos e cofactores NADP(H), o que é fundamental para a sobrevivência e a progressão das células cancerosas. Do mesmo modo, a Escherichia coli (E. coli) e os agentes patogénicos infecciosos potencialmente mortais, como o Staphylococcus aureus (SA) e o Mycobacterium tuberculosis (Mtb), são consideravelmente sensíveis a alterações do ambiente oxidativo intracelular. Assim, as pequenas moléculas que modulam os níveis de antioxidantes e/ou aumentam as ERO intracelulares podem perturbar o ambiente oxidativo celular e induzir a morte celular, pelo que podem servir como novas terapêuticas. Apresenta-se aqui um conjunto de abordagens que envolvem a modulação das ROS nas células como estratégia para combater o cancro e as bactérias.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 72 pp. Portugiesisch.…

  • Language: Italian

    Published by Edizioni Sapienza Feb 2024, 2024

    6207135601 / 9786207135608

    • Softcover
    • Print on Demand

    Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 50.77 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -I ROS sono una 'spada a doppio taglio': Evitare la persistente resistenza ai farmaci nel cancro e nei batteri è fondamentale per ripristinare la salute negli esseri umani e spinge le strategie di intervento. Una proprietà distinta del fenotipo del cancro è l'aumento del metabolismo del glucosio e dello stress ossidativo. Le specie reattive dell'ossigeno (ROS) sono sottoprodotti metabolici della respirazione aerobica e sono responsabili del mantenimento dell'omeostasi redox nelle cellule. L'equilibrio redox e lo stress ossidativo sono orchestrati da enzimi antiossidanti, tioli ridotti e cofattori NADP(H), il che è fondamentale per la sopravvivenza e la progressione delle cellule tumorali. Allo stesso modo, l'Escherichia coli (E. coli) e i patogeni infettivi pericolosi per la vita come lo Staphylococcus aureus (SA) e il Mycobacterium tuberculosis (Mtb) sono sensibilmente sensibili ai cambiamenti dell'ambiente ossidativo intracellulare. Pertanto, piccole molecole che modulano i livelli di antiossidanti e/o aumentano i ROS intracellulari potrebbero disturbare l'ambiente ossidativo cellulare e indurre la morte cellulare, e quindi potrebbero servire come nuovi farmaci. Qui viene presentata una serie di approcci che prevedono la modulazione dei ROS nelle cellule come strategia per colpire il cancro e i batteri.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken Italienisch.…

  • Language: German

    Published by Verlag Unser Wissen Feb 2024, 2024

    6207135547 / 9786207135547

    • Softcover
    • Print on Demand

    Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

    5-star seller
    Contact seller

    Condition: New

    £ 31.29

    £ 50.77 shipping 
    Ships from Germany to U.S.A.

    Quantity: 1 available

    Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -ROS ein 'zweischneidiges Schwert': Die Umgehung der hartnäckigen Arzneimittelresistenz bei Krebs und Bakterien ist für die Wiederherstellung der Gesundheit des Menschen von entscheidender Bedeutung und gibt den Anstoß für Interventionsstrategien. Eine besondere Eigenschaft des Krebsphänotyps ist ein erhöhter Glukosestoffwechsel und oxidativer Stress. Reaktive Sauerstoffspezies (ROS) sind metabolische Nebenprodukte der aeroben Atmung und für die Aufrechterhaltung der Redox-Homöostase in Zellen verantwortlich. Das Redox-Gleichgewicht und der oxidative Stress werden durch antioxidative Enzyme, reduzierte Thiole und NADP(H)-Kofaktoren gesteuert, was für das Überleben und Fortschreiten von Krebszellen entscheidend ist. Auch Escherichia coli (E. coli) und lebensbedrohliche Infektionserreger wie Staphylococcus aureus (SA) und Mycobacterium tuberculosis (Mtb) reagieren sehr empfindlich auf Veränderungen des intrazellulären oxidativen Milieus. Daher könnten kleine Moleküle, die den Gehalt an Antioxidantien modulieren und/oder die intrazelluläre ROS erhöhen, das zelluläre oxidative Milieu stören und den Zelltod auslösen und somit als neuartige Therapeutika dienen. Hier wird eine Reihe von Ansätzen vorgestellt, bei denen die ROS-Modulation in Zellen als Strategie zur Bekämpfung von Krebs und Bakterien eingesetzt wird.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 72 pp. Deutsch.…