Reactive Oxygen Species (ROS) Based Therapeutics : Role of ROS in therapeutics and drug resistance in cancer and bacteria
Language: English
Published by LAP LAMBERT Academic Publishing, 2017
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 36.33
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Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - ROS a 'double edged sword': Evading persistent drug resistance in cancer and bacteria is quintessential to restore health in humans, and impels intervention strategies. A distinct property of the cancer phenotype is enhanced glucose metabolism and oxidative stress. Reactive oxygen species (ROS) are metabolic byproducts of aerobic respiration and are responsible for maintaining redox homeostasis in cells. Redox balance and oxidative stress are orchestrated by antioxidant enzymes, reduced thiols and NADP(H) cofactors, which is critical for cancer cells survival and progression. Similarly, Escherichia coli (E. coli) and life-threatening infectious pathogens such as Staphylococcus aureus (SA) and Mycobacterium tuberculosis (Mtb) are appreciably sensitive to changes in the intracellular oxidative environment. Thus, small molecules that modulate antioxidant levels and/or enhance intracellular ROS could disturb the cellular oxidative environment and induce cell death, and hence could serve as novel therapeutics. Presented here are a collection of approaches that involve ROS modulation in cells as a strategy to target cancer and bacteria.…
Seller Inventory # 9783330069152
- Title
- Reactive Oxygen Species (ROS) Based Therapeutics : Role of ROS in therapeutics and drug resistance in cancer and bacteria
- Author
- Dharmaraja Allimuthu
- Publisher
- LAP LAMBERT Academic Publishing
- Publication year
- 2017
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3330069155
- ISBN 13
- 9783330069152
- Item weight
- 113 grams
- Dimensions
- 220x150x5 mm
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