Statistical Methods Drug Combination (29 results)

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Published by Routledge, 2020
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Published by Routledge, 2020
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Published by Taylor & Francis Ltd, 2020
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Published by Routledge, 2020
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Published by CRC Press, 2020
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Condition: New. Wei Zhao, Harry YangThe growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical co.

Language: English
Published by Taylor & Francis Ltd, 2020
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Taschenbuch. Condition: Neu. Statistical Methods in Drug Combination Studies | Wei Zhao (u. a.) | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2020 | Taylor & Francis Ltd | EAN 9780367738624 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu.

Language: English
Published by Chapman and Hall/CRC, 2014
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Published by Chapman and Hall/CRC, 2014
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Published by Taylor & Francis Group, 2014
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Published by Chapman and Hall/CRC, 2014
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Language: English
Published by Taylor & Francis Group, 2014
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Language: English
Published by Chapman & Hall, 2015
Series: Chapman & Hall/CRC Biostatistics, Book 48 of 155. Book 48 of 155 - Chapman & Hall/CRC Biostatistics
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical computing, make…s it possible to apply these emerging statistical methods in in vitro and in vivo drug combination assessments. However, despite these advances, no book has served as a single source of information for statistical methods in drug combination research, nor has there been any guidance for experimental strategies.Statistical Methods in Drug Combination Studies fills that gap, covering all aspects of drug combination research, from designing in vitro drug combination studies to analyzing clinical trial data. Featuring contributions from researchers in industry, academia, and regulatory agencies, this comprehensive reference:Describes statistical models used to characterize dose-response patterns of monotherapies and evaluate the combination drug synergyOffers guidance for estimating interaction indices and constructing their associated confidence intervals to assess drug interactionIntroduces a practical and innovative Bayesian approach to Phase I cancer trials, including actual trial examples to illustrate useExamines strategies in the fixed-dose combination therapy clinical development via case studies stemming from regulatory reviewsEvaluates computational tools and software packages used to apply novel statistical methods in combination drug developmentStatistical Methods in Drug Combination Studies provides researchers with a solid understanding of the available statistical methods and computational tools and how to apply them in drug combination studies. The book is equally useful for statisticians to become better equipped to deal with drug combination study design and analysis in their practice. 240 pp. Englisch.

Language: English
Published by Taylor & Francis, Chapman And Hall/CRC, 2020
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical computing, makes it…possible to apply these emerging statistical methods in in vitro and in vivo drug combination assessments. However, despite these advances, no book has served as a single source of information for statistical methods in drug combination research, nor has there been any guidance for experimental strategies.Statistical Methods in Drug Combination Studies fills that gap, covering all aspects of drug combination research, from designing in vitro drug combination studies to analyzing clinical trial data. Featuring contributions from researchers in industry, academia, and regulatory agencies, this comprehensive reference:Describes statistical models used to characterize dose-response patterns of monotherapies and evaluate the combination drug synergyOffers guidance for estimating interaction indices and constructing their associated confidence intervals to assess drug interactionIntroduces a practical and innovative Bayesian approach to Phase I cancer trials, including actual trial examples to illustrate useExamines strategies in the fixed-dose combination therapy clinical development via case studies stemming from regulatory reviewsEvaluates computational tools and software packages used to apply novel statistical methods in combination drug developmentStatistical Methods in Drug Combination Studies provides researchers with a solid understanding of the available statistical methods and computational tools and how to apply them in drug combination studies. The book is equally useful for statisticians to become better equipped to deal with drug combination study design and analysis in their practice.

Language: English
Published by Taylor & Francis Group, 2014
Series: Chapman & Hall/CRC Biostatistics, Book 48 of 155. Book 48 of 155 - Chapman & Hall/CRC Biostatistics
- Hardcover
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Language: English
Published by CRC Press, 2014
Series: Chapman & Hall/CRC Biostatistics, Book 48 of 155. Book 48 of 155 - Chapman & Hall/CRC Biostatistics
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Wei Zhao, Harry YangThe growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled… with advances in statistical co.

Language: English
Published by Chapman & Hall, 2015
Series: Chapman & Hall/CRC Biostatistics, Book 48 of 155. Book 48 of 155 - Chapman & Hall/CRC Biostatistics
- Hardcover
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Language: English
Published by Chapman And Hall/CRC, 2014
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - This comprehensive reference covers all aspects of drug combination research, from designing in vitro drug combination studies to analyzing clinical trial data. Featuring contributions from researchers in industry, academia, and regulatory agen…cies, this balanced text provides researchers with a solid understanding of the available statistical methods and computational tools and how to apply them in drug combination studies. The book is equally useful for statisticians to become better equipped to deal with drug combination study design and analysis in their practice.