Pharmacokinetic Study Solid Dispersion by Nitave Sachin (7 results)

Condition: New.

Taschenbuch. Condition: Neu. Pharmacokinetic study of solid dispersion tablet of Kariyat extract | Pharmacokinetic, tissue distribution and stability study of solid dispersion tablet of Adrographis paniculata extract | Sachin Annasaheb Nitave (u. a.) | Taschenbuch | Englisch | 2022 | LAP LAMBERT Academic Publishing | EAN 9786205487143 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Condition: New. Print on Demand.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Andrographolide is poorly soluble in water, it has low oral bioavailability. Objective of present study was to enhance solubility of andrographolide through solid dispersion technique and conversion it into tablet dosage form. Solubility of extract was found to be more from solid dispersion prepared by using Soluplus than that of prepared using PEG 6000. Compatibility study using IR, DSC and XRD showed that, ethanolic extract is compatible with soluplus and can be used for preparation of stable formulation. Pharmacokinetic study showed that, there was a significant increase in absorption of andrographolide from solid dispersion tablet. andrographolide. The relative bioavailability of andrographolide from solid dispersion tablet to that of pure andrographolide was found to be 177.59±14.6%. From tissue distribution study it can be concluded that, concentration of andrographolide in all tissues get increased in animals in which solid dispersion tablet was administered orally. It reveals that absorption of andrographolide is getting increased after conversion of extract into solid dispersion tablet. Accelerated stability study indicates that prepared solid dispersion was stable. 68 pp. Englisch.…

Condition: New. PRINT ON DEMAND.

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Andrographolide is poorly soluble in water, it has low oral bioavailability. Objective of present study was to enhance solubility of andrographolide through solid dispersion technique and conversion it into tablet dosage form. Solubility of extract was foun.…

Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Andrographolide is poorly soluble in water, it has low oral bioavailability. Objective of present study was to enhance solubility of andrographolide through solid dispersion technique and conversion it into tablet dosage form. Solubility of extract was found to be more from solid dispersion prepared by using Soluplus than that of prepared using PEG 6000. Compatibility study using IR, DSC and XRD showed that, ethanolic extract is compatible with soluplus and can be used for preparation of stable formulation. Pharmacokinetic study showed that, there was a significant increase in absorption of andrographolide from solid dispersion tablet. andrographolide. The relative bioavailability of andrographolide from solid dispersion tablet to that of pure andrographolide was found to be 177.59±14.6%. From tissue distribution study it can be concluded that, concentration of andrographolide in all tissues get increased in animals in which solid dispersion tablet was administered orally. It reveals that absorption of andrographolide is getting increased after conversion of extract into solid dispersion tablet. Accelerated stability study indicates that prepared solid dispersion was stable.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 68 pp. Englisch.…