Formulation Evaluation Fast Dissolving by Pandit Vinay (17 results)
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Published by LAP LAMBERT Academic Publishing 2020-01-15, 2020
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Taschenbuch. Condition: Neu. Formulation and Evaluation of Fast Dissolving Tablet of Clopidogrel | Fast Dissolving Tablets | Vinay Pandit (u. a.) | Taschenbuch | 108 S. | Englisch | 2020 | LAP LAMBERT Academic Publishing | EAN 9786200535078 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078… Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
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Taschenbuch. Condition: Neu. Formulation and Evaluation of Fast Dissolving Film of Chlorpromazine | Fast Dissolving Film of Chlorpromazine | Vinay Pandit (u. a.) | Taschenbuch | 116 S. | Englisch | 2020 | LAP LAMBERT Academic Publishing | EAN 9786202524209 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher La…ndstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
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Published by LAP LAMBERT Academic Publishing Apr 2020, 2020
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Emesis is the involuntary and forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Receptors on the floor of the ventricle of the brain represent a chemo-receptor trigger zone, known as the a…rea postrema, stimulation of which can lead to vomiting. Chlorpromazine HCl is formulated as a sublingual film. The films formed by HPMC K-15 at a concentration of 120 mg showed the desirable character for a sublingual film. The optimized films formed were subjected to evaluation parameters viz. Tensile Strength, Disintegration, In-vitro dissolution, Ex-vivo Permeation studies and In-vivo studies and the results complied with the available statistical data. In-vitro dissolution studies were analyzed and Higuchi model was found to be the best fit model for In-vitro dissolution studies with a regression value of 0.9248. Ex-vivo permeation studies showed fivefold enhanced permeation of drug from films as compared to pure drug. In conclusion, a sublingual film of Chlorpromazine HCl may result in better patient compliance, quick onset of action and enhanced bio-availability. 116 pp. Englisch.
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Published by LAP LAMBERT Academic Publishing Jan 2020, 2020
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present investigation involves formulation and evaluation of fast dissolving tablet of clopidogrel, which is used to prevent coronary disorder. Platelet aggregation is part of the sequence events leading to the formulation of a…thrombus (clot). Antiplatelet therapy with one or more drugs decreases the ability of blood clot to form by interfering with the platelet activation process in primary homeostasis. Tablets were formulated by three different methods Viz., Direct compression method, Solid dispersion method and Sublimation method. Different excipients such as, crospovidone as super disintegrants, croscarmellose as superdisintegrant, magnesium stearate as lubricant, talc as glidant etc. were used. Based on in-vitro release studies tablets prepared by sublimation method clopidogrel was selected as optimizes formulation. In-vitro release studies indicated more than 95% release of drug in 30 mins. The accurate stability studies indicated no change in in-vitro release and other property of the tablet. Thus sublimation method can be a promising strategy in enhancing the solubility and dissolution studies of clopidogrel bisulphate. 108 pp. Englisch.
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Pandit VinayDr. Vinay Pandit is working as Professor and Head, Department of Pharmaceutics, Laureate Institute of Pharmacy, Kathog, Jawlamukhi, Himachal Pradesh. He has published a number of research ar…ticles in various reputed journ.
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Pandit VinayDr. Vinay Pandit is working as a Professor and Head, Department of Pharmaceutics, Laureate Institute of Pharmacy. His current area of research is a Novel drug delivery system and fast dissol…ving technology. He has a numbe.
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Published by LAP LAMBERT Academic Publishing Apr 2020, 2020
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Emesis is the involuntary and forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Receptors on the floor of the ventricle of the brain represent a chemo-receptor trigger zone, known as the area…postrema, stimulation of which can lead to vomiting. Chlorpromazine HCl is formulated as a sublingual film. The films formed by HPMC K-15 at a concentration of 120 mg showed the desirable character for a sublingual film. The optimized films formed were subjected to evaluation parameters viz. Tensile Strength, Disintegration, In-vitro dissolution, Ex-vivo Permeation studies and In-vivo studies and the results complied with the available statistical data. In-vitro dissolution studies were analyzed and Higuchi model was found to be the best fit model for In-vitro dissolution studies with a regression value of 0.9248. Ex-vivo permeation studies showed fivefold enhanced permeation of drug from films as compared to pure drug. In conclusion, a sublingual film of Chlorpromazine HCl may result in better patient compliance, quick onset of action and enhanced bio-availability.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 116 pp. Englisch.
Language: English
Published by LAP LAMBERT Academic Publishing Jan 2020, 2020
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The present investigation involves formulation and evaluation of fast dissolving tablet of clopidogrel, which is used to prevent coronary disorder. Platelet aggregation is part of the sequence events leading to the formulation of a thro…mbus (clot). Antiplatelet therapy with one or more drugs decreases the ability of blood clot to form by interfering with the platelet activation process in primary homeostasis. Tablets were formulated by three different methods Viz., Direct compression method, Solid dispersion method and Sublimation method. Different excipients such as, crospovidone as super disintegrants, croscarmellose as superdisintegrant, magnesium stearate as lubricant, talc as glidant etc. were used. Based on in-vitro release studies tablets prepared by sublimation method clopidogrel was selected as optimizes formulation. In-vitro release studies indicated more than 95% release of drug in 30 mins. The accurate stability studies indicated no change in in-vitro release and other property of the tablet. Thus sublimation method can be a promising strategy in enhancing the solubility and dissolution studies of clopidogrel bisulphate.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 108 pp. Englisch.
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The present investigation involves formulation and evaluation of fast dissolving tablet of clopidogrel, which is used to prevent coronary disorder. Platelet aggregation is part of the sequence events leading to the formulation of a throm…bus (clot). Antiplatelet therapy with one or more drugs decreases the ability of blood clot to form by interfering with the platelet activation process in primary homeostasis. Tablets were formulated by three different methods Viz., Direct compression method, Solid dispersion method and Sublimation method. Different excipients such as, crospovidone as super disintegrants, croscarmellose as superdisintegrant, magnesium stearate as lubricant, talc as glidant etc. were used. Based on in-vitro release studies tablets prepared by sublimation method clopidogrel was selected as optimizes formulation. In-vitro release studies indicated more than 95% release of drug in 30 mins. The accurate stability studies indicated no change in in-vitro release and other property of the tablet. Thus sublimation method can be a promising strategy in enhancing the solubility and dissolution studies of clopidogrel bisulphate.
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Emesis is the involuntary and forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Receptors on the floor of the ventricle of the brain represent a chemo-receptor trigger zone, known as the area p…ostrema, stimulation of which can lead to vomiting. Chlorpromazine HCl is formulated as a sublingual film. The films formed by HPMC K-15 at a concentration of 120 mg showed the desirable character for a sublingual film. The optimized films formed were subjected to evaluation parameters viz. Tensile Strength, Disintegration, In-vitro dissolution, Ex-vivo Permeation studies and In-vivo studies and the results complied with the available statistical data. In-vitro dissolution studies were analyzed and Higuchi model was found to be the best fit model for In-vitro dissolution studies with a regression value of 0.9248. Ex-vivo permeation studies showed fivefold enhanced permeation of drug from films as compared to pure drug. In conclusion, a sublingual film of Chlorpromazine HCl may result in better patient compliance, quick onset of action and enhanced bio-availability.
