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Condition: New. 1st edition NO-PA16APR2015-KAP.
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Seller: Ria Christie Collections, Uxbridge, United Kingdom
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Condition: New. Highlights key structure-based drug design (SBDD) innovations to generate potency and selectivity vs. KRASAnalyzes medicinal chemistry case histories for seminal contributions to the KRAS fieldProvides an overview of in vitro and i.
Language: English
Published by Elsevier - Health Sciences Division Okt 2024, 2024
ISBN 10: 0443218617 ISBN 13: 9780443218613
Seller: AHA-BUCH GmbH, Einbeck, Germany
Taschenbuch. Condition: Neu. Neuware - KRAS Drug Discovery: Past, Present and Future is a comprehensive overview of the state-of-the-art medicinal chemistry approaches towards targeting the formerly undruggable oncogene, KRAS. It includes Seminal medicinal chemistry case histories of KRASG12C inhibitors such as Sotorosib, the first approved KRASG12C inhibitor for NSCLC, alongside the latest advances towards identification of in vivo tools and development candidates targeting KRAS G12D, KRAS G13C and other mutations. The book also provides the reader with a comprehensive overview of the in vitro assay systems, in vivo pharmacology xenograft models and chemical biology tools available to characterize small molecule inhibitors of KRAS.
Seller: Brook Bookstore On Demand, Napoli, NA, Italy
Condition: new. Questo è un articolo print on demand.
Language: English
Published by Elsevier Science Ltd, 2024
ISBN 10: 0443218617 ISBN 13: 9780443218613
Seller: Revaluation Books, Exeter, United Kingdom
Paperback. Condition: Brand New. 500 pages. 9.00x6.00x9.25 inches. In Stock. This item is printed on demand.