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Regulation of the cell cycle phosphatase CDC25C in acute leukemia
Language: English
Published by Our Knowledge Publishing, 2025
ISBN 10: 6208902770 ISBN 13: 9786208902773
Condition: New.
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Regulation of the cell cycle phosphatase CDC25C in acute leukemia
Language: English
Published by Our Knowledge Publishing, 2025
ISBN 10: 6208902770 ISBN 13: 9786208902773
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Seller rating 5 out of 5 stars
£ 40.88
£ 3.29 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketPAP. Condition: New. New Book. Shipped from UK. Established seller since 2000.
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Régulation de la phosphatase du cycle cellulaire CDC25C dans la leucémie aiguë (French Edition)
Language: French
Published by Editions Notre Savoir, 2025
ISBN 10: 6208902789 ISBN 13: 9786208902780
Condition: New.
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R?gulation de la phosphatase du cycle cellulaire CDC25C dans la leuc?mie aigu?
Language: French
Published by Editions Notre Savoir, 2025
ISBN 10: 6208902789 ISBN 13: 9786208902780
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Seller rating 5 out of 5 stars
£ 40.88
£ 3.29 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketPAP. Condition: New. New Book. Shipped from UK. Established seller since 2000.
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Regulation of the cell cycle phosphatase CDC25C in acute leukemia
Language: English
Published by Our Knowledge Publishing, 2025
ISBN 10: 6208902770 ISBN 13: 9786208902773
Condition: New.
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Regulação da fosfatase CDC25C do ciclo celular na leucemia aguda (Portuguese Edition)
Language: Portuguese
Published by Edições Nosso Conhecimento, 2025
ISBN 10: 6208902819 ISBN 13: 9786208902810
Condition: New.
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Regulacja fosfatazy cyklu komórkowego CDC25C w ostrej bia?aczce (Polish Edition)
Language: Polish
Published by Wydawnictwo Nasza Wiedza, 2025
ISBN 10: 6208902762 ISBN 13: 9786208902766
Condition: New.
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Regula??o da fosfatase CDC25C do ciclo celular na leucemia aguda
Language: Portuguese
Published by Edi??es Nosso Conhecimento, 2025
ISBN 10: 6208902819 ISBN 13: 9786208902810
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Seller rating 5 out of 5 stars
£ 40.88
£ 3.29 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketPAP. Condition: New. New Book. Shipped from UK. Established seller since 2000.
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Regolazione della fosfatasi del ciclo cellulare CDC25C nella leucemia acuta
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Seller rating 5 out of 5 stars
£ 40.88
£ 3.29 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketPAP. Condition: New. New Book. Shipped from UK. Established seller since 2000.
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Regulacja fosfatazy cyklu kom?rkowego CDC25C w ostrej bialaczce
Language: Polish
Published by Wydawnictwo Nasza Wiedza, 2025
ISBN 10: 6208902762 ISBN 13: 9786208902766
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Seller rating 5 out of 5 stars
£ 40.88
£ 3.29 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketPAP. Condition: New. New Book. Shipped from UK. Established seller since 2000.
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R?gulation de la phosphatase du cycle cellulaire CDC25C dans la leuc?mie aigu? (French Edition)
Language: French
Published by Editions Notre Savoir, 2025
ISBN 10: 6208902789 ISBN 13: 9786208902780
Condition: New.
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Regula??o da fosfatase CDC25C do ciclo celular na leucemia aguda (Portuguese Edition)
Language: Portuguese
Published by Edições Nosso Conhecimento, 2025
ISBN 10: 6208902819 ISBN 13: 9786208902810
Condition: New.
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Regulacja fosfatazy cyklu kom?rkowego CDC25C w ostrej bialaczce (Polish Edition)
Language: Polish
Published by Wydawnictwo Nasza Wiedza, 2025
ISBN 10: 6208902762 ISBN 13: 9786208902766
Condition: New.
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Regulation der Zellzyklus-Phosphatase CDC25C in der akuten Leukämie
Language: German
Published by Südwestdeutscher Verlag für Hochschulschriften, 2019
ISBN 10: 6202323302 ISBN 13: 9786202323307
Taschenbuch. Condition: Neu. Regulation der Zellzyklus-Phosphatase CDC25C in der akuten Leukämie | Florian Perner | Taschenbuch | 80 S. | Deutsch | 2019 | Südwestdeutscher Verlag für Hochschulschriften | EAN 9786202323307 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
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Pathologie nicht-neoplastischer Lungenerkrankungen : Praxishandbuch
Language: German
Published by Springer, J.B. Metzler, 2024
ISBN 10: 3662670720 ISBN 13: 9783662670729
Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Das Praxisbuch für die tägliche Diagnostik am MikroskopNeben den klinischen und radiologischen Untersuchungen kommt der histopathologischen Untersuchung von Lungengewebeproben eine entscheidungsrelevante Bedeutung zu. In diagnostisch schwierigen oder zweifelhaften Fällen kann durch die histologische Begutachtung betroffener Lungenareale eine Diagnosesicherung erzielt und therapeutisch relevante Differentialdiagnosen ausgeschlossen werden.Die Diagnostik nicht-neoplastischer Lungenerkrankungen ist oft eine große Herausforderung für den diagnostizierenden Pathologen. Unter den knappen Zeitressourcen aber auch angesichts der stetig zunehmenden Anzahl neu definierter bzw. weiter verfeinerter Entitäten, ist es kaum möglich, den Überblick zu behalten oder gar sämtliche wesentlichen Kriterien zur Diagnosestellung aus der Erinnerung abzurufen.Dieses Buch bietet eine kurze, übersichtliche Darstellung der einzelnen Krankheitsentitäten und der diagnostischen Kriterien für die Untersuchung von Lungengewebeproben.Es begleitet den Pathologen bei der täglichen Arbeit am Mikroskop und erläutert kurz und knapp, welche diagnostischen Kriterien im konkreten Fall greifen und welche Differentialdiagnosen zu beachten sind. Die Autoren legen Wert auf eine standardisierte und übersichtliche Darstellung der einzelnen Krankheitsentitäten. Fallstricken, die zunächst die Diagnose in die falsche Richtung lenken können, werden aufgezeigt.Algorithmen erlauben dem Leser, gezielt den korrekten diagnostischen Pfad einzuschlagen und zügig zur richtigen Diagnose zu finden.Ein einmaliges Praxishandbuch für die tägliche Diagnostik des Pathologen.
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Regulation of the cell cycle phosphatase CDC25C in acute leukemia
Language: English
Published by Omniscriptum, Our Knowledge Publishing, 2025
ISBN 10: 6208902770 ISBN 13: 9786208902773
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Internal tandem duplications in the FLT3 receptor gene (FLT3-ITD) are found in approximately 30% of patients with acute myeloid leukemia (AML). This oncogene influences various functions of the AML cell and leads to uncontrolled proliferation. Clinically, FLT3-ITD is associated with a poor prognosis in patients with AML. In this study, the influence of FLT3-ITD on the phosphatase CDC25C, which as a cell cycle regulator significantly influences the control of cell division, was investigated. The experiments described here showed that CDC25C is phosphorylated by FLT3-ITD and activated in an uncontrolled manner. In the leukemia cell model, a primarily protective effect of CDC25C was shown in the presence of oncogenic stress. The genetically non-intact cells were increasingly prevented from dividing by CDC25C. However, the simultaneous presence of the FLT3-ITD mutation resulted in a loss of this protective function. The significance of the mechanism described here therefore lies in the control of the response of the leukemia cell to damage within the DNA. However, CDC25C does not have an oncogenic function in the classical sense. 64 pp. Englisch.
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Regulación de la fosfatasa del ciclo celular CDC25C en la leucemia aguda
Language: Spanish
Published by Ediciones Nuestro Conocimiento Mai 2025, 2025
ISBN 10: 6208902797 ISBN 13: 9786208902797
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 68 pp. Spanisch.
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Regulation of the cell cycle phosphatase CDC25C in acute leukemia
Language: English
Published by Our Knowledge Publishing, 2025
ISBN 10: 6208902770 ISBN 13: 9786208902773
Condition: New. Print on Demand.
-
Regulation of the cell cycle phosphatase CDC25C in acute leukemia
Language: English
Published by Our Knowledge Publishing, 2025
ISBN 10: 6208902770 ISBN 13: 9786208902773
Condition: New. PRINT ON DEMAND.
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Regulation of the cell cycle phosphatase CDC25C in acute leukemia
Language: English
Published by Our Knowledge Publishing Mai 2025, 2025
ISBN 10: 6208902770 ISBN 13: 9786208902773
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Internal tandem duplications in the FLT3 receptor gene (FLT3-ITD) are found in approximately 30% of patients with acute myeloid leukemia (AML). This oncogene influences various functions of the AML cell and leads to uncontrolled proliferation. Clinically, FLT3-ITD is associated with a poor prognosis in patients with AML. In this study, the influence of FLT3-ITD on the phosphatase CDC25C, which as a cell cycle regulator significantly influences the control of cell division, was investigated. The experiments described here showed that CDC25C is phosphorylated by FLT3-ITD and activated in an uncontrolled manner. In the leukemia cell model, a primarily protective effect of CDC25C was shown in the presence of oncogenic stress. The genetically non-intact cells were increasingly prevented from dividing by CDC25C. However, the simultaneous presence of the FLT3-ITD mutation resulted in a loss of this protective function. The significance of the mechanism described here therefore lies in the control of the response of the leukemia cell to damage within the DNA. However, CDC25C does not have an oncogenic function in the classical sense.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 64 pp. Englisch.
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Régulation de la phosphatase du cycle cellulaire CDC25C dans la leucémie aiguë
Language: French
Published by Editions Notre Savoir Mai 2025, 2025
ISBN 10: 6208902789 ISBN 13: 9786208902780
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 68 pp. Französisch.
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Regulation of the cell cycle phosphatase CDC25C in acute leukemia
Language: English
Published by Our Knowledge Publishing, 2025
ISBN 10: 6208902770 ISBN 13: 9786208902773
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Internal tandem duplications in the FLT3 receptor gene (FLT3-ITD) are found in approximately 30% of patients with acute myeloid leukemia (AML). This oncogene influences various functions of the AML cell and leads to uncontrolled proliferation. Clinically, FLT3-ITD is associated with a poor prognosis in patients with AML. In this study, the influence of FLT3-ITD on the phosphatase CDC25C, which as a cell cycle regulator significantly influences the control of cell division, was investigated. The experiments described here showed that CDC25C is phosphorylated by FLT3-ITD and activated in an uncontrolled manner. In the leukemia cell model, a primarily protective effect of CDC25C was shown in the presence of oncogenic stress. The genetically non-intact cells were increasingly prevented from dividing by CDC25C. However, the simultaneous presence of the FLT3-ITD mutation resulted in a loss of this protective function. The significance of the mechanism described here therefore lies in the control of the response of the leukemia cell to damage within the DNA. However, CDC25C does not have an oncogenic function in the classical sense.
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Regulación de la fosfatasa del ciclo celular CDC25C en la leucemia aguda
Language: Spanish
Published by Ediciones Nuestro Conocimiento Mai 2025, 2025
ISBN 10: 6208902797 ISBN 13: 9786208902797
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Las duplicaciones internas en tándem del gen receptor FLT3 (FLT3-ITD) se encuentran en aproximadamente el 30% de los pacientes con leucemia mieloide aguda (LMA). Este oncogén influye en diversas funciones de la célula de la LMA y conduce a una proliferación incontrolada. Clínicamente, FLT3-ITD se asocia a un mal pronóstico en pacientes con LMA. En este estudio, se investigó la influencia de FLT3-ITD en la fosfatasa CDC25C, que como regulador del ciclo celular influye significativamente en el control de la división celular. Los experimentos aquí descritos mostraron que CDC25C es fosforilada por FLT3-ITD y activada de forma incontrolada. En el modelo celular de leucemia, se demostró un efecto principalmente protector de CDC25C en presencia de estrés oncogénico. CDC25C impidió cada vez más la división de las células genéticamente no intactas. Sin embargo, la presencia simultánea de la mutación FLT3-ITD provocó una pérdida de esta función protectora. La importancia del mecanismo aquí descrito radica, por tanto, en el control de la respuesta de la célula leucémica a los daños en el ADN. Sin embargo, CDC25C no tiene una función oncogénica en el sentido clásico.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 68 pp. Spanisch.
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Regulación de la fosfatasa del ciclo celular CDC25C en la leucemia aguda
Language: Spanish
Published by Ediciones Nuestro Conocimiento, 2025
ISBN 10: 6208902797 ISBN 13: 9786208902797
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering.
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R?gulation de la phosphatase du cycle cellulaire CDC25C dans la leuc?mie aigu? (French Edition)
Language: French
Published by Editions Notre Savoir, 2025
ISBN 10: 6208902789 ISBN 13: 9786208902780
Condition: New. Print on Demand.
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R?gulation de la phosphatase du cycle cellulaire CDC25C dans la leuc?mie aigu? (French Edition)
Language: French
Published by Editions Notre Savoir, 2025
ISBN 10: 6208902789 ISBN 13: 9786208902780
Condition: New. PRINT ON DEMAND.
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Régulation de la phosphatase du cycle cellulaire CDC25C dans la leucémie aiguë
Language: French
Published by Editions Notre Savoir Mai 2025, 2025
ISBN 10: 6208902789 ISBN 13: 9786208902780
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Des duplications internes en tandem du gène du récepteur FLT3 (FLT3-ITD) sont présentes chez environ 30% des patients atteints de leucémie myéloïde aiguë (LMA). Cet oncogène influence différentes fonctions de la cellule LAM et entraîne une prolifération incontrôlée. Cliniquement, la FLT3-ITD est associée à un mauvais pronostic chez les patients atteints de LAM. Dans ce travail, l'influence de la FLT3-ITD sur la phosphatase CDC25C, qui, en tant que régulateur du cycle cellulaire, influence de manière déterminante le contrôle de la division cellulaire, a été étudiée. Les expériences décrites ici ont pu montrer que CDC25C est phosphorylée et activée de manière incontrôlée par la FLT3-ITD. Dans le modèle de cellules de leucémie, un effet protecteur primaire de CDC25C a été observé en présence d'un stress oncogène. Les cellules génétiquement non intactes ont été davantage empêchées de se diviser par CDC25C. Cependant, la présence simultanée de la mutation FLT3-ITD a entraîné une perte de cette fonction protectrice. L'importance du mécanisme décrit ici réside donc dans le contrôle de la réponse de la cellule leucémique aux dommages au sein de l'ADN. En revanche, CDC25C n'a pas de fonction oncogène au sens classique du terme.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken Französisch.
