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Published by Taylor & Francis Ltd, 2018
ISBN 10: 1138199931 ISBN 13: 9781138199934
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Taschenbuch. Condition: Neu. Neuware - This book explores the diverse capabilities of optical probes and presents various approaches used to design, develop, and implement these powerful and versatile tools. It examines the use of optical probes to detect and track numerous molecular processes in living cells, including GTPase and kinase activities, metabolic signals, RNA, and histone modifications. The book also covers sophisticated imaging techniques and equipment used to visualize and track optical probes and discusses emerging techniques that are expanding optical probe-based approaches into new biological frontiers.
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Published by Taylor & Francis Group, 2015
ISBN 10: 1466510110 ISBN 13: 9781466510111
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Published by Taylor & Francis Group, 2015
ISBN 10: 1466510110 ISBN 13: 9781466510111
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Dr. Jin Zhang is a professor of pharmacology, neuroscience, and oncology in the Johns Hopkins University School of Medicine with a joint appointment in the Department of Chemical and Biomolecular Engineering in the Johns Hopkins Universi.
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Optical probes, particularly the fluorescent varieties, enable researchers to observe cellular events in real time and with great spatial resolution. Optical Probes in Biology explores the diverse capabilities of these powerful and versatile tools and presents various approaches used to design, develop, and implement them.The book examines the use of optical probes to detect and track numerous molecular processes in living cells, including GTPase and kinase activities, membrane lipids, voltage, metal ions, metabolic signals, RNA, and histone modifications. It critically reviews the different probe designs and delves into the strategies for developing new fluorescent protein varieties with enhanced capabilities. It also covers sophisticated imaging techniques and equipment, such as intensity and lifetime-based fluorescence microscopy methods, used to visualize and track optical probes.In addition, the book goes beyond live-cell tracking to discuss the growing application of activity-based probes for performing pharmacological drug screening and probing molecular processes in living animals. It also discusses emerging techniques that are expanding optical probe-based approaches into new biological frontiers.With contributions from top international scientists, this book offers a thorough overview of the latest optical probes in cell biology and biochemistry. Both newcomers and established researchers will discover how to incorporate state-of-the-art optical probes and fluorescence imaging into their research.