Marion Darnaud (10 results)
- Softcover
Seller: Books Puddle, New York, NY, U.S.A.Books Puddle
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- Softcover
Seller: Revaluation Books, Exeter, , United KingdomRevaluation Books
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Paperback. Condition: Brand New. 332 pages. 8.66x5.91x0.75 inches. In Stock.
- Softcover
Seller: preigu, Osnabrück, Germanypreigu
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Taschenbuch. Condition: Neu. Creation of a DNA aptamer biosensor for the detection of heart failure | Marion Darnaud | Taschenbuch | 332 S. | Englisch | 2016 | LAP Lambert Academic Publishing | EAN 9783659829239 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | A…nbieter: preigu.
- Softcover
Seller: Mispah books, Redhill, SURRE, United KingdomMispah books
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paperback. Condition: New. NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
Language: English
Published by LAP Lambert Academic Publishing Feb 2016 2016
- Softcover
- Print on Demand
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, , GermanyBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Aptamers are small nucleic acid molecules, which are used to bind specific targets in ways similar to antibodies. They offer advantages in terms of cost and reproducibility of production, stability and capability for biochemical mod…ifications. This work focused on discovering a new DNA aptamer biosensor for brain natriuretic peptide (BNP), a biomarker of the early stages of heart failure. A library of random DNA sequences was generated by the polymerase chain reaction and evaluated for specific and sensitive binding to BNP using an in vitro selection technique known as systematic evolution of ligands by exponential enrichment (SELEX). After 15 SELEX cycles using BNP immobilised on an affinity chromatography column, selected aptamers were subcloned and sequenced. The aptamer exhibiting the best specificity towards BNP was shown to adopt a G-quadruplex structure of the anti-parallel type. This aptamer was used to devise an enzyme-linked oligonucleotide assay using surface enhanced Raman spectroscopy allowing the detection of BNP down to the picomolar range. In addition, a quick colorimetric assay was developed on the concept of target-mediated aggregation of gold nanoparticles. 332 pp. Englisch.
- Softcover
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Seller: Majestic Books, Hounslow, , United KingdomMajestic Books
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- Softcover
- Print on Demand
Seller: Biblios, frankfurt am main, HESSE, GermanyBiblios
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- Softcover
- Print on Demand
Seller: moluna, Greven, , Germanymoluna
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Darnaud MarionMarion Darnaud is a R&D Biosciences Manager. She graduated with a PhD in Pure and Applied Chemistry in 2008 at the University of Strathclyde, Glasgow, UK. Her PhD work, under the supervisi…on of Prof. Duncan Graham, was .
Language: English
Published by LAP Lambert Academic Publishing Feb 2016 2016
- Softcover
- Print on Demand
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Aptamers are small nucleic acid molecules, which are used to bind specific targets in ways similar to antibodies. They offer advantages in terms of cost and reproducibility of production, stability and capability for biochemical modific…ations. This work focused on discovering a new DNA aptamer biosensor for brain natriuretic peptide (BNP), a biomarker of the early stages of heart failure. A library of random DNA sequences was generated by the polymerase chain reaction and evaluated for specific and sensitive binding to BNP using an in vitro selection technique known as systematic evolution of ligands by exponential enrichment (SELEX). After 15 SELEX cycles using BNP immobilised on an affinity chromatography column, selected aptamers were subcloned and sequenced. The aptamer exhibiting the best specificity towards BNP was shown to adopt a G-quadruplex structure of the anti-parallel type. This aptamer was used to devise an enzyme-linked oligonucleotide assay using surface enhanced Raman spectroscopy allowing the detection of BNP down to the picomolar range. In addition, a quick colorimetric assay was developed on the concept of target-mediated aggregation of gold nanoparticles.Books on Demand GmbH, Überseering 33, 22297 Hamburg 332 pp. Englisch.
- Softcover
- Print on Demand
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Aptamers are small nucleic acid molecules, which are used to bind specific targets in ways similar to antibodies. They offer advantages in terms of cost and reproducibility of production, stability and capability for biochemical modifica…tions. This work focused on discovering a new DNA aptamer biosensor for brain natriuretic peptide (BNP), a biomarker of the early stages of heart failure. A library of random DNA sequences was generated by the polymerase chain reaction and evaluated for specific and sensitive binding to BNP using an in vitro selection technique known as systematic evolution of ligands by exponential enrichment (SELEX). After 15 SELEX cycles using BNP immobilised on an affinity chromatography column, selected aptamers were subcloned and sequenced. The aptamer exhibiting the best specificity towards BNP was shown to adopt a G-quadruplex structure of the anti-parallel type. This aptamer was used to devise an enzyme-linked oligonucleotide assay using surface enhanced Raman spectroscopy allowing the detection of BNP down to the picomolar range. In addition, a quick colorimetric assay was developed on the concept of target-mediated aggregation of gold nanoparticles.
