Khan Sehrish (36 results)

Condition: New. In English.

Condition: New. Print on Demand.

Condition: New.

Condition: New. Print on Demand.

Condition: New.

Condition: New. Print on Demand.

Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Bachelor Thesis from the year 2014 in the subject Biology - Micro- and Molecular Biology, grade: 1, International Islamic University, language: English, abstract: Alopecia is a broad term including many forms of hereditary hair loss resulting from genetic defects affecting hair growth cycle or hair structure that vary in age of onset, severity and associated ectodermal abnormalities. The inheritance pattern of alopecia can be autosomal dominant, autosomal recessive or X-linked. Various mutations in several genes on different chromosomes are being identified which are involved in pathogenesis of inherited autosomal recessive alopecia.In present research, two families (A&B) with isolated hereditary alopecia, residing in different zones of Pakistan were ascertained. The mode of inheritance inferred as autosomal recessive. One family was subjected to mutation screening while on other, polymorphic microsatellite markers was used for the purpose of homozygosity mapping to explicate the gene defect. Phenotypic analysis of family A shows the characteristic clinical features of hypotrichosis with sparse hair on head and rest of body and with no associated abnormality. Gene linked to this family in previous research was CDH3. So, splice-junction site and sixteen exons of this gene were sequenced but were negative for functonal sequence variant. This clearly shows mutation must be present in regulatory region of this gene. In family B, affected individual's shows clinical features of atrichia with papular lesions (APL) which is rare autosomal recessive disorder, characterized by occurrence of complete hair loss with the development of keratin-filled cysts. Known candidate genes (DSG4, HR, LIPH and LPAR6) were tested for homozygosity mapping via polymorphic microsatellite markers. Genotyping data showed no linkage to any of the candidate loci and therefore, their involvement in causing atrichia with papular lesions in this family is not supported.…

Paperback. Condition: Brand New. 88 pages. 8.66x5.91x0.20 inches. In Stock.

PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Condition: New.

Condition: New.

Condition: As New. Unread book in perfect condition.

Condition: New. In English.

Condition: New. pp. XXXI, 179 240 illus., 236 illus. in color. 2019th edition NO-PA16APR2015-KAP.

Paperback. Condition: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Paperback. Condition: Brand New. 212 pages. 9.25x6.10x0.50 inches. In Stock.

Condition: New.

Condition: As New. Unread book in perfect condition.

Condition: New. In English.

paperback. Condition: New. NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Condition: New. 1st ed. 2019 edition NO-PA16APR2015-KAP.

Hardcover. Condition: Brand New. 212 pages. 9.25x6.25x0.75 inches. In Stock.

Hardcover. Condition: New. NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Condition: New. Print on Demand.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Bachelor Thesis from the year 2014 in the subject Biology - Micro- and Molecular Biology, grade: 1, International Islamic University, language: English, abstract: Alopecia is a broad term including many forms of hereditary hair loss resulting from genetic defects affecting hair growth cycle or hair structure that vary in age of onset, severity and associated ectodermal abnormalities. The inheritance pattern of alopecia can be autosomal dominant, autosomal recessive or X-linked. Various mutations in several genes on different chromosomes are being identified which are involved in pathogenesis of inherited autosomal recessive alopecia.In present research, two families (A&B) with isolated hereditary alopecia, residing in different zones of Pakistan were ascertained. The mode of inheritance inferred as autosomal recessive. One family was subjected to mutation screening while on other, polymorphic microsatellite markers was used for the purpose of homozygosity mapping to explicate the gene defect. Phenotypic analysis of family A shows the characteristic clinical features of hypotrichosis with sparse hair on head and rest of body and with no associated abnormality. Gene linked to this family in previous research was CDH3. So, splice-junction site and sixteen exons of this gene were sequenced but were negative for functonal sequence variant. This clearly shows mutation must be present in regulatory region of this gene. In family B, affected individual's shows clinical features of atrichia with papular lesions (APL) which is rare autosomal recessive disorder, characterized by occurrence of complete hair loss with the development of keratin-filled cysts. Known candidate genes (DSG4, HR, LIPH and LPAR6) were tested for homozygosity mapping via polymorphic microsatellite markers. Genotyping data showed no linkage to any of the candidate loci and therefore, their involvement in causing atrichia with papular lesions in this family is not supported. 88 pp. Englisch.…

Condition: New. PRINT ON DEMAND.

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Khan Zeeshan AhmadZeeshan Ahmad Khan is a young and energetic research Scholar in the field of Finance. In a very short span of time, he has worked with both National & Multinational organizations in Pakistan i.e. British Council, Y. …

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Farooq MuhammadMuhammad Farooq From Pakistan Distt and Tehsil Mardan KPK Pakistan M Phil Food science and Technology Gold Medalist, PhD Scholar in Northwest Agriculture & Forestry University China.Muhammad Farooq MP.hil (Food T. …

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Zeeshan SehrishSehrish Zeeshan is the young and energetic research scholar of Pakistan. In a very short span of time, she has worked with top educational institutions of her country. She is also working on the development and promoti.…