Janarthanan Krishnamoorthy (7 results)

Condition: New. pp. 120.

Taschenbuch. Condition: Neu. NMR chemical exchange in mapping the protein-ligand binding site | Mapping the binding site of ligands to proteins using chemical exchange parameters by NMR spectroscopy | Janarthanan Krishnamoorthy (u. a.) | Taschenbuch | 120 S. | Englisch | 2011 | LAP LAMBERT Academic Publishing | EAN 9783844397352 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Chemical exchange is one of the most extensively studied phenomenon in NMR spectroscopy to identify and establish the mechanism of interaction between molecules of interest (protein-ligand). While the exchange regimes are classified into three types based on the experimentally observed spectral pattern, the theory underlying all these three regimes is general. In order to delineate the mechanism of interaction through chemical exchange, mechanism dependent ligand correction and evaluation of population are necessary. For a simple system the data analysis is easier compared to the complex systems, where both the ligand correction and parameter optimization are to be performed simultaneously. This analytical difficulty has been overcome by adopting a genetic algorithm based approach for data analysis using numerical method. The computational implementation is available in the form of open source C programs: 'Auto-FACE' for fast chemical exchange and 'AUTOMEX' for all exchange regimes. 120 pp. Englisch.

Condition: New. Print on Demand pp. 120 2:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on Creme w/Gloss Lam.

Condition: New. PRINT ON DEMAND pp. 120.

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Krishnamoorthy JanarthananDr. Janarthanan obtained his bachelor s degree from Madras medical college, and master s from Anna University. He carried out his phd at National University of Singapore under the supervision of Assoc. Pr.

Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Chemical exchange is one of the most extensively studied phenomenon in NMR spectroscopy to identify and establish the mechanism of interaction between molecules of interest (protein-ligand). While the exchange regimes are classified into three types based on the experimentally observed spectral pattern, the theory underlying all these three regimes is general. In order to delineate the mechanism of interaction through chemical exchange, mechanism dependent ligand correction and evaluation of population are necessary. For a simple system the data analysis is easier compared to the complex systems, where both the ligand correction and parameter optimization are to be performed simultaneously. This analytical difficulty has been overcome by adopting a genetic algorithm based approach for data analysis using numerical method. The computational implementation is available in the form of open source C programs: 'Auto-FACE' for fast chemical exchange and 'AUTOMEX' for all exchange regimes.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 120 pp. Englisch.