Gurusubramanian Guruswami (59 results)

Condition: New. pp. 152.

Taschenbuch. Condition: Neu. Homology modelling of dipteran specific Cry proteins of Bt | Physicochemical and functional characterization, secondary structure prediction, model building and validation | Gurusubramanian Guruswami (u. a.) | Taschenbuch | 68 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783659570513 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Taschenbuch. Condition: Neu. Molecular Characterization and Phylogeny of Heliconiinae Butterflies | Gurusubramanian Guruswami (u. a.) | Taschenbuch | 176 S. | Englisch | 2016 | LAP LAMBERT Academic Publishing | EAN 9783659822827 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

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Softcover/Taschenbuch. Condition: Neu. Se llev? a cabo la caracterizaci?n fisicoqu?mica de cuatro prote?nas Cry y se interpretaron propiedades tales como el peso molecular, el pI, el EC, el AI, el GRAVY, la composici?n de amino?cidos y el ?ndice de inestabilidad. Los valores m?s altos de GRAVY y AI se observaron en Cry4Aa (0,827) y cry2Aa 1 (84,53). Se llev? a cabo la predicci?n de motivos, patrones, puentes disulfuro y estructura secundaria, as? como de regiones transmembranales y dominios de las prote?nas Cry, con el fin de realizar su caracterizaci?n funcional. Se utilizaron cuatro secuencias plantilla (1I5P, ADL6, 2C9K y 1W99) para el modelado por homolog?a (SwissModel y EsyPred3D) con el fin de predecir la estructura tridimensional. La puntuaci?n LG de las secuencias plantilla 1I5P, ADL6, 2C9K y 1W99, mostrada en SwissModel y EsyPred, indicaba que se trataba de un modelo extremadamente bueno. Los sitios activos de la prote?na se determinaron mediante el servidor CASTp y se situaban entre los residuos 83 y 239. El ?rea y el volumen del bolsillo oscilaban entre 422,9 y 5828, y entre 518,1 y 3719,2, respectivamente. La validaci?n de los modelos estructurales se llev? a cabo utilizando PROCHECK. Los modelos se verificaron adem?s con WHAT IF. Ambas estructuras se analizaron mediante la herramienta ProFunc, que revel? que ten?an funciones diferentes, ya que presentaban estructuras y sitios activos distintos. Por lo tanto, la estructura desempe?a un papel fundamental a la hora de determinar su funci?n. Sprache: Spanisch Gewicht in Gramm: 107.…

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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This manual offers a stand-alone reading companion, unique in simplifying the practical components of Bioinformatics in a unique and user-friendly manner. It covers the practical component of syllabi used at most leading universities and discusses the most extensively used tools and methodologies in Bioinformatics.Research in the biological scienceshas made tremendous stridesin recent years due in part to the increased automation in datageneration.At the same time,storing, managing and interpreting huge volumes of data has become one of the most challenging tasksfor scientists. Thesetwo aspectshave ultimately necessitated the application of computers, giving rise to a highly interdisciplinary discipline-Bioinformatics.Despite the richness of bioinformatics resources and methods, the exposure of life sciences undergraduates and postgraduates to bioinformatics is extremely limited. Though the internet offers various tools for free, and provides guides for using them, it fails to help users interpret the processed data. Moreover, most sites fail to update their help pagesto accommodate software upgrades. Thoughthe market is flooded with books discussing the theoretical concepts in Bioinformatics, a manual of this kindis rarely found.The contentdevelopedto meet the needs of readers fromdiverse background and to incorporate the syllabi of undergraduate and postgraduate courses at various universities.…

Condition: New. pp. 298.

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Gebundene Ausgabe. Condition: Neu. This manual offers a stand-alone reading companion, unique in simplifying the practical components of Bioinformatics in a unique and user-friendly manner. It covers the practical component of syllabi used at most leading universities and discusses the most extensively used tools and methodologies in Bioinformatics. Research in the biological sciences has made tremendous strides in recent years due in part to the increased automation in data generation. At the same time, storing, managing and interpreting huge volumes of data has become one of the most challenging tasks for scientists. These two aspects have ultimately necessitated the application of computers, giving rise to a highly interdisciplinary discipline-Bioinformatics. Despite the richness of bioinformatics resources and methods, the exposure of life sciences undergraduates and postgraduates to bioinformatics is extremely limited. Though the internet offers various tools for free, and provides guides for using them, it fails to help users interpret the processed data. Moreover, most sites fail to update their help pages to accommodate software upgrades. Though the market is flooded with books discussing the theoretical concepts in Bioinformatics, a manual of this kind is rarely found. The content developed to meet the needs of readers from diverse background and to incorporate the syllabi of undergraduate and postgraduate courses at various universities. Sprache: Englisch Gewicht in Gramm: 565.…

Hardcover. Condition: Brand New. 283 pages. 9.50x6.50x1.00 inches. In Stock.

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Softcover/Taschenbuch. Condition: Neu. Une caract?risation physico-chimique de 4 prot?ines Cry a ?t? r?alis?e, permettant d'interpr?ter des propri?t?s telles que la masse mol?culaire, le pI, l'EC, l'AI, le GRAVY, la composition en acides amin?s et l'indice d'instabilit? Les valeurs GRAVY et AI les plus ?lev?es ont ?t? observ?es pour Cry4Aa (0,827) et cry2Aa1 (84,53). La pr?diction des motifs, des structures, des ponts disulfure, de la structure secondaire, des r?gions transmembranaires et des domaines des prot?ines Cry a ?t? r?alis?e ? des fins de caract?risation fonctionnelle. Quatre s?quences mod?les (1I5P, ADL6, 2C9K et 1W99) ont ?t? utilis?es pour la mod?lisation par homologie (SwissModel et EsyPred3D) afin de pr?dire la structure en 3D. Le score LG des s?quences mod?les 1I5P, ADL6, 2C9K et 1W99, tel qu'indiqu? par SwissModel et EsyPred, indiquait un mod?le d'excellente qualit? Les sites actifs de la prot?ine ont ?t? d?termin?s par le serveur CASTp et se situaient entre 83 et 239. La surface et le volume de la poche variaient respectivement entre 422,9 et 5 828, et entre 518,1 et 3 719,2. La validation des mod?les structuraux a ?t? r?alis?e ? l'aide de PROCHECK. Les mod?les ont ensuite ?t? v?rifi?s ? l'aide de WHAT IF. Les deux structures ont ?t? analys?es ? l'aide de l'outil ProFunc, qui a montr? qu'elles avaient des fonctions diff?rentes en raison de leurs structures et sites actifs distincts. La structure joue donc un r?le essentiel dans la d?termination de la fonction de la prot?ine. Sprache: Französisch Gewicht in Gramm: 107.…

Softcover/Taschenbuch. Condition: Neu. Es wurde eine physikalisch-chemische Charakterisierung von 4 Cry-Proteinen durchgef?hrt und Eigenschaften wie Molekulargewicht, pI, EC, AI, GRAVY, Aminos?urezusammensetzung und Instabilit?tsindex ausgewertet. Die h?chsten GRAVY- und AI-Werte wurden bei Cry4Aa (0,827) und cry2Aa1 (84,53) festgestellt. Zur funktionellen Charakterisierung wurden Vorhersagen zu Motiven, Mustern, Disulfidbr?cken sowie zur Sekund?rstruktur, zu Transmembranregionen und Dom?nen der Cry-Proteine durchgef?hrt. Vier Template-Sequenzen (1I5P, ADL6, 2C9K und 1W99) wurden f?r die Homologiemodellierung (SwissModel und EsyPred3D) verwendet, um die 3D-Struktur vorherzusagen. Der in SwissModel und EsyPred angezeigte LG-Score f?r die Templates 1I5P, ADL6, 2C9K und 1W99 wies auf ein ?u?erst gutes Modell hin. Die aktiven Zentren des Proteins wurden mithilfe des CASTp-Servers bestimmt und lagen im Bereich von 83 bis 239. Die Fl?che und das Volumen der Bindungsstelle lagen bei 422,9 - 5828 bzw. 518,1 - 3719,2. Die Validierung der Strukturmodelle erfolgte mit PROCHECK. Die Modelle wurden zus?tzlich mit WHAT IF ?berpr?ft. Beide Strukturen wurden mit dem ProFunc-Tool analysiert, das zeigte, dass sie unterschiedliche Funktionen aufweisen, da sie unterschiedliche Strukturen und aktive Zentren hatten. Somit spielt die Struktur eine entscheidende Rolle bei der Bestimmung ihrer Funktion. De Gewicht in Gramm: 107.…

Softcover/Taschenbuch. Condition: Neu. ? stata effettuata la caratterizzazione fisico-chimica di 4 proteine Cry e sono state interpretate propriet? quali peso molecolare, pI, EC, AI, GRAVY, composizione aminoacidica e indice di instabilit? I valori pi? elevati di GRAVY e AI sono stati riscontrati in Cry4Aa (0,827) e cry2Aa 1 (84,53). Ai fini della caratterizzazione funzionale, sono state effettuate previsioni relative a motivi, schemi, ponti disolfuro, struttura secondaria, regioni transmembranarie e domini delle proteine Cry. Per la modellazione per omologia (SwissModel ed EsyPred3D) sono state utilizzate quattro sequenze modello (1I5P, ADL6, 2C9K e 1W99) al fine di prevedere la struttura tridimensionale. Il punteggio LG per i modelli 1I5P, ADL6, 2C9K e 1W99, riportato da SwissModel ed EsyPred, indicava modelli di ottima qualit? I siti attivi delle proteine sono stati determinati dal server CASTp e variavano da 83 a 239. L'area e il volume della tasca variavano rispettivamente da 422,9 a 5828 e da 518,1 a 3719,2. La validazione dei modelli strutturali ? stata effettuata utilizzando PROCHECK. I modelli sono stati ulteriormente verificati con WHAT IF. Entrambe le strutture sono state analizzate utilizzando lo strumento ProFunc, che ha evidenziato funzioni diverse in quanto presentavano strutture e siti attivi differenti. Pertanto, la struttura svolge un ruolo fondamentale nel determinarne la funzione. Sprache: Italienisch Gewicht in Gramm: 107.…

Softcover/Taschenbuch. Condition: Neu. Foi realizada a caracteriza??o f?sico-qu?mica de 4 prote?nas Cry, tendo-se interpretado propriedades como o peso molecular, o pI, o EC, o AI, o GRAVY, a composi??o de amino?cidos e o ?ndice de instabilidade. Os valores mais elevados de GRAVY e AI foram observados na Cry4Aa (0,827) e na cry2Aa 1 (84,53). Para a caracteriza??o funcional, foram realizadas previs?es de motivos, padr?es, pontes dissulfureto e estrutura secund?ria, bem como de regi?es transmembranares e dom?nios das prote?nas Cry. Foram utilizadas quatro sequ?ncias-modelo (1I5P, ADL6, 2C9K e 1W99) para a modela??o por homologia (SwissModel e EsyPred3D) com vista a prever a estrutura 3D. A pontua??o LG para as sequ?ncias-modelo 1I5P, ADL6, 2C9K e 1W99, apresentada no SwissModel e no EsyPred, indicou que se tratava de um modelo extremamente bom. Os s?tios ativos da prote?na foram determinados pelo servidor CASTp e variaram entre 83 e 239. A ?rea e o volume da cavidade variaram entre 422,9 e 5828 e entre 518,1 e 3719,2, respetivamente. A valida??o dos modelos estruturais foi realizada utilizando o PROCHECK. Os modelos foram posteriormente verificados com o WHAT IF. Ambas as estruturas foram analisadas utilizando a ferramenta ProFunc, que revelou que possu?am fun??es diferentes, uma vez que apresentavam estruturas e s?tios ativos distintos. Assim, a estrutura desempenha um papel vital na determina??o da sua fun??o. Gewicht in Gramm: 107.…

Softcover/Taschenbuch. Condition: Neu. Przeprowadzono charakterystyk? fizykochemiczn? 4 bi?ek Cry i zinterpretowano takie w??ciwo?ci, jak masa cz?steczkowa, pI, EC, AI, GRAVY, sk?ad aminokwasowy oraz wsk?nik niestabilno?ci. Najwy?sze warto?ci wsk?nik?w GRAVY i AI stwierdzono dla bi?ka Cry4Aa (0,827) oraz cry2Aa 1 (84,53). W celu charakterystyki funkcjonalnej przeprowadzono przewidywanie motyw?w, wzorc?w, mostk?w disiarczkowych oraz struktury drugorz?dowej, region?w transb?onowych i domen bi?ek Cry. Do modelowania homologicznego (SwissModel i EsyPred3D) w celu przewidzenia struktury 3D wykorzystano cztery sekwencje szablonowe (1I5P, ADL6, 2C9K i 1W99). Wynik LG dla szablon?w 1I5P, ADL6, 2C9K i 1W99, przedstawiony w programach SwissModel i EsyPred, wskazyw? na wyj?tkowo dobre dopasowanie modelu. Miejsca aktywne bi?ka zost?y okre?lone za pomoc? serwera CASTp i mie?ci?y si? w przedziale 83-239. Powierzchnia i obj?to?? kieszeni wynosi?y odpowiednio 422,9-5828 oraz 518,1-3719,2. Walidacj? modeli strukturalnych przeprowadzono przy u?yciu programu PROCHECK. Modele zost?y dodatkowo sprawdzone za pomoc? programu WHAT IF. Obie struktury zost?y przeanalizowane przy u?yciu narz?dzia ProFunc, kt?re wykaz?o, ?e pe?ni? one r?ne funkcje, poniew? charakteryzow?y si? odmiennymi strukturami i miejscami aktywnymi. W zwi?zku z tym struktura odgrywa kluczow? rol? w okre?laniu funkcji bi?ka. Gewicht in Gramm: 107. …

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Physico-chemical characterization of 4 cry proteins was done and interpreted the properties such as molecular weight, pI, EC, AI, GRAVY, amino acid composition and instability index. The highest GRAVY and AI value were found in Cry4Aa (0.827) and cry2Aa 1(84.53). Prediction of motifs, patterns, disulfide bridges and secondary structure, transmembrane regions and domains of Cry proteins were performed for functional characterization. Four template sequences (1I5P, ADL6, 2C9K and 1W99) were used for homology modeling (Swiss Model and EsyPred3D) to predict the 3D structure. The LG score for 1I5P, ADL6, 2C9K and 1W99 template shown in Swissmodel and EsyPred was extremely a good model. Active sites of the protein was determined by CASTp server and ranged from 83-239. The pocket area and volume ranged from 422.9 - 5828 and 518.1-3719.2, respectively. The validation for structure models was performed by using PROCHECK. The models were further checked with WHAT IF. Both the structures were analyzed using ProFunc tool which showed to have different functions as they had different structures and active sites. Thereby the structure plays a vital role in determining its function. 68 pp. Englisch.…

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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Guruswami GurusubramanianGurusubramanian Guruswami, PhD:Studied Zoology at University of Madras. Associate Professor at Mizoram University, Tanhril, Aizawl, Mizoram, India.Vikas Kumar Roy, PhD:Studied Zoology at Banaras Hindu Univers. …

PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vanlalhruaia KhawlhringDr. K. Vanlalhruaia, Consultant SVBDCP, Govt. of Mizoram, India. Department of Zoology, Mizoram University, Aizawl-796004, Mizoram, IndiaMosquitoes (Diptera: Cu.…