Borggrefe Tilman (60 results)

Hardcover. Condition: Very Good. 1st Edition. Oversized hardcover, xi + 376 pages, NOT ex-library. Weight 926g. Clean and bright pages with unmarked text, free of inscriptions and stamps, firmly bound. A short crease in the lower inner corners of a portion of pages. Faint marks on page edges externally. Boards show a few scratches. Issued without a dust jacket. -- A vital resource for understanding the regulatory elements that control gene expression, this volume provides an extensive collection of methodologies for studying enhancers and promoters, crucial components in the field of molecular biology. It includes step-by-step protocols, detailed techniques, and insights from leading experts, covering various approaches to analyze and manipulate these genetic elements. The book addresses the latest advancements and technologies used in gene regulation research, making it an essential reference for molecular biologists, geneticists, and researchers focused on transcriptional regulation.…

Condition: New. In English.

Condition: New. 2022. Paperback. . . . . .

Condition: New.

Condition: New.

Condition: New.

Condition: New.

Condition: New. 2022. Paperback. . . . . . Books ship from the US and Ireland.

Condition: New. In English.

Condition: As New. Unread book in perfect condition.

Condition: As New. Unread book in perfect condition.

Taschenbuch. Condition: Neu. Molecular Mechanisms of Notch Signaling | Tilman Borggrefe (u. a.) | Taschenbuch | Advances in Experimental Medicine and Biology | xxvii | Englisch | 2018 | Springer | EAN 9783030077891 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Condition: New.

Condition: New.

Condition: New.

Condition: New.

Condition: New. In English.

Hardcover. Condition: Brand New. 387 pages. 10.00x7.01x0.90 inches. In Stock.

Condition: New.

Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression. Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated. This book is not only intended for experts but it should also be a usefulresource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments.…

Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering.

Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression. Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated. This book is not only intended for experts but it should also be a usefulresource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments.…

Hardcover. Condition: New. NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Paperback. Condition: New. NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Hardcover. Condition: Brand New. 300 pages. 10.00x7.00x10.00 inches. In Stock.

Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as particular examples of leukemia fusion proteins that contain a part of a transcription factor. In the given chapters covering each one particular example, the function of transcription factors is characterized in normal as well as leukemic contexts.New technologies such as ChIP-Seq or RNA-Seq, that make use of genome-wide sequencing, have shown that such master regulators of blood cell development often work in combinatorial fashion and, when dysregulated, results in leukemogenesis.This book is not only intended for experts but it should also be a useful resource for younger scientists or scientists from other disciplines, who may use this book as a stimulating starting point for further discoveries and/ or translational endeavors.…

Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as particular examples of leukemia fusion proteins that contain a part of a transcription factor. In the given chapters covering each one particular example, the function of transcription factors is characterized in normal as well as leukemic contexts.New technologies such as ChIP-Seq or RNA-Seq, that make use of genome-wide sequencing, have shown that such master regulators of blood cell development often work in combinatorial fashion and, when dysregulated, results in leukemogenesis.This book is not only intended for experts but it should also be a useful resource for younger scientists or scientists from other disciplines, who may use this book as a stimulating starting point for further discoveries and/ or translational endeavors.…

Condition: new. Questo è un articolo print on demand.

Condition: new. Questo è un articolo print on demand.

Condition: new. Questo è un articolo print on demand.