Alexander V Karasev (40 results)

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Condition: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An additional advantage from the public health point of view is high safety compared to animal systems, which is important for vaccine production: there are no known plant pathogens capable of replicating in animals, and in humans in particular. A particular antigen or a protein has to be expressed in a plant using one of many available platforms; this antigen/protein subsequently needs to be purified or processed, and later formulated into a vaccine or a therapeutic; these need to be delivered to a human or animal body via an appropriate route. Naturally, all these vaccines and therapeutics must be subjected to regulatory approvals prior to their use. Thus, the challenge is to adapt plant-based platforms for production of cost-efficient biomedicals that can be approved by FDA for use as vaccine components or therapeutics which will be competitive against existing vaccines and drugs.This volume attempts to address the entire spectrum of challenges facing the nascent field of plant-based biomedicals, from the selection of an appropriate production platform to specific methods of downstream processing and regulatory approval issues.…

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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An additional advantage from the public health point of view is high safety compared to animal systems, which is important for vaccine production: there are no known plant pathogens capable of replicating in animals, and in humans in particular. A particular antigen or a protein has to be expressed in a plant using one of many available platforms; this antigen/protein subsequently needs to be purified or processed, and later formulated into a vaccine or a therapeutic; these need to be delivered to a human or animal body via an appropriate route. Naturally, all these vaccines and therapeutics must be subjected to regulatory approvals prior to their use. Thus, the challenge is to adapt plant-based platforms for production of cost-efficient biomedicals that can be approved by FDA for use as vaccine components or therapeutics which will be competitive against existing vaccines and drugs.This volume attempts to address the entire spectrum of challenges facing the nascent field of plant-based biomedicals, from the selection of an appropriate production platform to specific methods of downstream processing and regulatory approval issues.…

Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An additional advantage from the public health point of view is high safety compared to animal systems, which is important for vaccine production: there are no known plant pathogens capable of replicating in animals, and in humans in particular. A particular antigen or a protein has to be expressed in a plant using one of many available platforms; this antigen/protein subsequently needs to be purified or processed, and later formulated into a vaccine or a therapeutic; these need to be delivered to a human or animal body via an appropriate route. Naturally, all these vaccines and therapeutics must be subjected to regulatory approvals prior to their use. Thus, the challenge is to adapt plant-based platforms for production of cost-efficient biomedicals that can be approved by FDA for use as vaccine components or therapeutics which will be competitive against existing vaccines and drugs.This volume attempts to address the entire spectrum of challenges facing the nascent field of plant-based biomedicals, from the selection of an appropriate production platform to specific methods of downstream processing and regulatory approval issues.…

Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Potato virus Y (PVY) infects a wide host range mainly within the Solanaceae and is distributed worldwide. PVY is transmitted by more than 40 aphid species in a non persistent manner. Isolates of the PVY species are highly variable at biological, serological and molecular levels. Epidemiological studies have highlighted the emergence of distinct potato PVY variants able to induce necroses on potato tubers. Due to the lack of efficient resistance to PVY isolates inducing necrotic symptoms in cultivated varieties and the plant-to-plant transmission of isolates through the daughter tubers, PVY has become the most economically important virus for the potato industry. The review offers an overview of several decades of research on PVY but also focuses on the latest data obtained by expert on PVY worldwide on the biological characteristics of PVY, interactions between aphids-hosts, its evolution and management. Identified knowledge gaps to understand further PVY biology will be discussed.…

Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Potato virus Y (PVY) infects a wide host range mainly within the Solanaceae and is distributed worldwide. PVY is transmitted by more than 40 aphid species in a non persistent manner. Isolates of the PVY species are highly variable at biological, serological and molecular levels. Epidemiological studies have highlighted the emergence of distinct potato PVY variants able to induce necroses on potato tubers. Due to the lack of efficient resistance to PVY isolates inducing necrotic symptoms in cultivated varieties and the plant-to-plant transmission of isolates through the daughter tubers, PVY has become the most economically important virus for the potato industry. The review offers an overview of several decades of research on PVY but also focuses on the latest data obtained by expert on PVY worldwide on the biological characteristics of PVY, interactions between aphids-hosts, its evolution and management. Identified knowledge gaps to understand further PVY biology will be discussed.…

Condition: New. pp. x + 120.

Taschenbuch. Condition: Neu. Potato virus Y: biodiversity, pathogenicity, epidemiology and management | Christophe Lacomme (u. a.) | Taschenbuch | xi | Englisch | 2018 | Springer | EAN 9783319864938 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Condition: New. pp. 276 Softcover reprint of the original 1st ed. 2017 edition NO-PA16APR2015-KAP.

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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Potato virus Y (PVY) infects a wide host range mainly within the Solanaceae and is distributed worldwide. PVY is transmitted by more than 40 aphid species in a non persistent manner. Isolates of the PVY species are highly variable at biological, serological and molecular levels. Epidemiological studies have highlighted the emergence of distinct potato PVY variants able to induce necroses on potato tubers. Due to the lack of efficient resistance to PVY isolates inducing necrotic symptoms in cultivated varieties and the plant-to-plant transmission of isolates through the daughter tubers, PVY has become the most economically important virus for the potato industry. The review offers an overview of several decades of research on PVY but also focuses on the latest data obtained by expert on PVY worldwide on the biological characteristics of PVY, interactions between aphids-hosts, its evolution and management. Identified knowledge gaps to understand further PVY biology will be discussed. 276 pp. Englisch.…

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Potato virus Y (PVY) infects a wide host range mainly within the Solanaceae and is distributed worldwide. PVY is transmitted by more than 40 aphid species in a non persistent manner. Isolates of the PVY species are highly variable at biological, serological and molecular levels. Epidemiological studies have highlighted the emergence of distinct potato PVY variants able to induce necroses on potato tubers. Due to the lack of efficient resistance to PVY isolates inducing necrotic symptoms in cultivated varieties and the plant-to-plant transmission of isolates through the daughter tubers, PVY has become the most economically important virus for the potato industry. The review offers an overview of several decades of research on PVY but also focuses on the latest data obtained by expert on PVY worldwide on the biological characteristics of PVY, interactions between aphids-hosts, its evolution and management. Identified knowledge gaps to understand further PVY biology will be discussed. 276 pp. Englisch.…

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An additional advantage from the public health point of view is high safety compared to animal systems, which is important for vaccine production: there are no known plant pathogens capable of replicating in animals, and in humans in particular. A particular antigen or a protein has to be expressed in a plant using one of many available platforms; this antigen/protein subsequently needs to be purified or processed, and later formulated into a vaccine or a therapeutic; these need to be delivered to a human or animal body via an appropriate route. Naturally, all these vaccines and therapeutics must be subjected to regulatory approvals prior to their use. Thus, the challenge is to adapt plant-based platforms for production of cost-efficient biomedicals that can be approved by FDA for use as vaccine components or therapeutics which will be competitive against existing vaccines and drugs.This volume attempts to address the entire spectrum of challenges facing the nascent field of plant-based biomedicals, from the selection of an appropriate production platform to specific methods of downstream processing and regulatory approval issues. 132 pp. Englisch.…

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An additional advantage from the public health point of view is high safety compared to animal systems, which is important for vaccine production: there are no known plant pathogens capable of replicating in animals, and in humans in particular. A particular antigen or a protein has to be expressed in a plant using one of many available platforms; this antigen/protein subsequently needs to be purified or processed, and later formulated into a vaccine or a therapeutic; these need to be delivered to a human or animal body via an appropriate route. Naturally, all these vaccines and therapeutics must be subjected to regulatory approvals prior to their use. Thus, the challenge is to adapt plant-based platforms for production of cost-efficient biomedicals that can be approved by FDA for use as vaccine components or therapeutics which will be competitive against existing vaccines and drugs.This volume attempts to address the entire spectrum of challenges facing the nascent field of plant-based biomedicals, from the selection of an appropriate production platform to specific methods of downstream processing and regulatory approval issues. 132 pp. Englisch.…

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A timely overview of several decades of research on PVY, one of the most important plant viruses that will appeal to a broad academic audience (universities, public and private funded institutions) and the wide agri-biotech industry (gro.…

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An ad.…

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An ad.…

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A timely overview of several decades of research on PVY, one of the most important plant viruses that will appeal to a broad academic audience (universities, public and private funded institutions) and the wide agri-biotech industry (gro.…