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Softcover. Condition: Very Good. 1. Auflage. Unread, with a mimimum of shelfwear. Immediately dispatched from Germany.
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paperback. Condition: Fine. Open Books is a nonprofit social venture that provides literacy experiences for thousands of readers each year through inspiring programs and creative capitalization of books.
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Novel Insights in the Neurochemistry and Function of Pulmonary Sensory Receptors (Advances in Anatomy, Embryology and Cell Biology, 211)
Book 27 of 173: Advances in Anatomy, Embryology and Cell BiologySeller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 117.36
£ 11.98 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: New. In.
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Paperback. Condition: Brand New. 2012 edition. 130 pages. 9.25x6.25x0.25 inches. In Stock.
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Condition: New. 1st ed. 2021 edition NO-PA16APR2015-KAP.
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Paperback. Condition: Brand New. 117 pages. 9.25x6.10x0.51 inches. In Stock.
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This monograph sheds new light on pulmonary sensory receptors. Diving into the pulmonary microenvironment, the book focuses on the role of pulmonary neuroepithelial bodies (NEBs) as potential receptors and effectors, able to store and release neurotransmitters. It explores NEBs as potential stem cell niche and highlights the multidisciplinary approach taken to identify and study NEBs, including functional morphological investigation, live cell imaging, genetic models, and laser microdissection combined with gene expression analysis.Complexly organized NEBs are an integral part of the intrapulmonary airway epithelium of all air-breathing vertebrates. For decades a quest has been going on to unravel the functional significance of these intriguing structures that appear to be modified in the course of many pulmonary diseases. The NEB microenvironment (ME) is composed of organoid clusters of pulmonary neuroendocrine cells (PNECs) that are able to store and release neurotransmitters and are closely contacted by extensive nerve terminals, emphasizing a potential receptor/effector role and probable signalling to the central nervous system. PNECs are largely shielded from the airway lumen by a special type of Clara cells, the Clara-like cells, with potential stem cell characteristics. So far, functional studies of the pulmonary NEB ME revealed that PNECs can be activated by various mechanical and chemical stimuli, resulting in a calcium-mediated release of neurotransmitters. In the past decades, a number of publications have exposed NEBs as potential hypoxia sensors. Recent experimental evidence unveiled that the NEB ME is a quiescent stem cell niche in healthy postnatal lungs, and silencing may involve bone morphogenetic protein signalling mediated by vagal afferents. Only an integrated approach that takes all current information into account will be able to explain the full role of the pulmonary NEB ME in health and disease. This highly informative and carefully presented book, provides insights for researchers, PhD students with an interest in (bio)medical and veterinary science, especially in the field of the autonomic innervation of the lung, chemo-and mechanoreceptors.
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Novel Insights in the Neurochemistry and Function of Pulmonary Sensory Receptors
Book 27 of 173: Advances in Anatomy, Embryology and Cell BiologyLanguage: English
Published by Springer Berlin Heidelberg, 2011
ISBN 10: 3642227716 ISBN 13: 9783642227714
Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes supplementary material: sn.pub/extrasWith the advances of immunohistochemistry in combination with confocal microscopy, airway sensory receptor end-organs can now be examined and evaluated objectively. Based on their `neurochemical co.
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The Pulmonary Neuroepithelial Body Microenvironment
Book 173 of 173: Advances in Anatomy, Embryology and Cell BiologyLanguage: English
Published by Springer International Publishing, 2021
ISBN 10: 3030658163 ISBN 13: 9783030658168
Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Focuses on sensory nerves in the airwaysHighlights the multidisciplinary approach to study NEBsExplores NEBs potential as stem cell nicheDr. Inge Brouns&n.
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