Aging of the Genome (Paperback)

Jan Vijg

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Language: English

Published by Oxford University Press, Oxford, 2007

0198569238 / 9780198569237

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Paperback. Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recentadvances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleteriouseffects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change. Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. This book reviews the concept of genomic instability. It provides underlying biology of aging, driven by continuing demographic change. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

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Title
Aging of the Genome (Paperback)
Author
Jan Vijg
Publisher
Oxford University Press, Oxford
Publication year
2007
Condition
new
Binding
Paperback
Language
English
ISBN 10
0198569238
ISBN 13
9780198569237
Edition
1st Edition

CitiRetail

Stevenage, United Kingdom

5-star seller

AbeBooks seller since June 29, 2022

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