Wrong Mouse Behavioral Phenotyping by Crawley Jacqueline (20 results)

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Hardcover. Condition: Very Good. 1. It's a well-cared-for item that has seen limited use. The item may show minor signs of wear. All the text is legible, with all pages included. It may have slight markings and/or highlighting.

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Hardback. Condition: Very Good. Transgenic and knockout mutations provide a tremendously important means for understanding gene function, as well as for developing therapies for genetic diseases. This work discusses the effects of behavioral phenotyping of transgenic and knockout mutations on laboratory mice.…

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Hardcover. Condition: Very good. First Edition. First Edition. Hardcover. 10 1/4" X 7 1/4". xvi, 523pp. First edition, with full number line indicating first printing. Bound in glossy pictorial paper over boards. Mild rubbing and shelf wear to covers, corners, and edges of binding. Pages are clean and unmarked. Binding is firm and sound. ABOUT THIS BOOK: Learn how to conduct behavioral tests to phenotype mutant mice Dr. Jacqueline N. Crawley, author of the first and second editions of What's Wrong With My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field hundreds of calls and e-mails from molecular geneticists who ask just that: How do I run behavioral assays to find out what's wrong with my mouse? This book answers that question and many more, including what tests are available to discover an aberrant behavioral phenotype? Turn to What's Wrong With My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the second edition up to date with the latest science. In addition, the second edition includes two new chapters: Neurodevelopment and Neurodegeneration discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis. Putting It All Together recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, The Next Generation, examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor Web sites, suggestions for expert behavioral neuroscientist collaborators, and an extensive list of references, make this book a valuable and practical resource for students and researchers.(Publisher).…

Hardcover. Condition: Very Good. 2. It's a well-cared-for item that has seen limited use. The item may show minor signs of wear. All the text is legible, with all pages included. It may have slight markings and/or highlighting.

hardcover. Condition: Gut. 540 Seiten; 9780471471929.3 Gewicht in Gramm: 2.

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Hardcover. Condition: Brand New. 2nd edition. 523 pages. 10.25x7.25x1.25 inches. In Stock.

Hardcover. Condition: Brand New. 2nd edition. 523 pages. 10.25x7.25x1.25 inches. In Stock. This item is printed on demand.