Trapnell Bruce (26 results)

Condition: Sehr gut. Zustand: Sehr gut | Seiten: 452 | Sprache: Englisch | Produktart: Bücher | theRareLungDiseaseConsortium,anetworkof13USandinter- tionalsitesthatiscurrentlyconductingclinicaltrialsandstudiesinLAM,alphaone antitrypsin de ciency, pediatric interstitial lung disease, and PAP. It has been a rare privilegetoworkonsuchfascinatingdiseaseswithsuchcapableinvestigatorsf romall overtheworldoverthepast6years. v vi Preface Theformatforthisvolumeisunique. Mostchaptershavebeenauthoredbyacli- cianandabasicscientistwhoareexpertinthediseasetopicandunderly ingmolecular defect,respectively. Theirchargewastofocusonthegeneticbasisandmolecularpat- genesisofdisease,animalmodels,clinicalfeatures,diagnosticapproach,conventional managementandtreatment,andfuturetherapeutictargetsanddirections. Theintentwas nottoprovideabroadoverview,butrathertoshedlightonthemolecularmechanisms thatevoketheclinicalpresentationandengendertreatmentstrategiesforeachdisease. Wehopethatthisapproachwillproveusefulforpulmonarycliniciansandscientists alike. Wethankourwives,Holly,Jean,andVicky,fortheirsupportandindulgence with latenightemailsandwork- lledweekends,Dr. Roundsfortheinvitationtowritethe book,andalloftheauthorswhocontributed. FrancisMcCormack,MD RalphPanos,MD BruceTrapnell,MD Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 AClinicalApproachtoRareLungDiseases. . . . . . . . . . . . . . . . 1 RalphJ. Panos 2 ClinicalTrialsforRareLungDiseases. . . . . . . . . . . . . . . . . . . 31 JeffreyKrischer 3 IdiopathicandFamilialPulmonaryArterialHypertension . . . . . . . . 39 JeanM. Elwing,GailH. Deutsch,WilliamC. Nichols, andTimothyD. LeCras 4 Lymphangioleiomyomatosis. . . . . . . . . . . . . . . . . . . . . . . . 85 ElizabethP. HenskeandFrancisX. McCormack 5 AutoimmunePulmonaryAlveolarProteinosis. . . . . . . . . . . . . . . 111 BruceC. Trapnell,KohNakata,andYoshikazuInoue 6 MutationsinSurfactantProteinCandInterstitialLungDisease . . . . . 133 RalphJ. Panosan.

Condition: New. In.

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Condition: New. pp. 449.

Condition: New. pp. 452.

Condition: New. States that the study of rare lung disorders enhances our understanding of common pulmonary diseases and disease mechanisms such as fibrosis and emphysema. Editor(s): McCormack, Francis X.; Trapnell, Bruce C.; Panos, Ralph J. Series: Respiratory Medicine. Num Pages: 438 pages, 34 black & white tables, biography. BIC Classification: MJL. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 30. Weight in Grams: 1139. . 2010. Hardback. . . . .

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Paperback. Condition: Brand New. reprint edition. 438 pages. 10.00x7.01x1.07 inches. In Stock.

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Condition: New. States that the study of rare lung disorders enhances our understanding of common pulmonary diseases and disease mechanisms such as fibrosis and emphysema. Editor(s): McCormack, Francis X.; Trapnell, Bruce C.; Panos, Ralph J. Series: Respiratory Medicine. Num Pages: 438 pages, 34 black & white tables, biography. BIC Classification: MJL. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 30. Weight in Grams: 1139. . 2010. Hardback. . . . . Books ship from the US and Ireland.

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Condition: new. Questo è un articolo print on demand.

Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Comprehensive, state-of-the-art review of rare lung diseasesThoroughly sheds light on the molecular mechanisms that evoke the clinical presentation and engender treatment strategies for each rare lung diseaseCovers all aspects of such disorders as pulmonary.

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Comprehensive, state-of-the-art review of rare lung diseasesThoroughly sheds light on the molecular mechanisms that evoke the clinical presentation and engender treatment strategies for each rare lung diseaseCovers all aspects of such disorders as pulmonary.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Pulmonary Disease: Insights from Rare LungDisorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy-to-read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture's syndromes to Sarcoidosis and alpha one antitrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis ofPulmonary Disease: Insights from Rare Lung Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders. 452 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Pulmonary Disease: Insights from Rare LungDisorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy-to-read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture's syndromes to Sarcoidosis and alpha one antitrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis ofPulmonary Disease: Insights from Rare Lung Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders. 452 pp. Englisch.

Condition: New. Print on Demand pp. 449.

Condition: New. PRINT ON DEMAND pp. 449.

Condition: New. Print on Demand pp. 452 49 Illus. (27 Col.).

Buch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -A Clinical Approach to Rare Lung Diseases.- Clinical Trials for Rare Lung Diseases.- Idiopathic and Familial Pulmonary Arterial Hypertension.- Lymphangioleiomyomatosis.- Autoimmune Pulmonary Alveolar Proteinosis.- Mutations in Surfactant Protein C and Interstitial Lung Disease.- Hereditary Haemorrhagic Telangiectasia.- Hermansky-Pudlak Syndrome.- Alpha-1 Antitrypsin Deficiency.- The Marfan Syndrome.- Surfactant Deficiency Disorders: SP-B and ABCA3.- Pulmonary Capillary Hemangiomatosis.- Anti-glomerular Basement Disease: Goodpasture's Syndrome.- Primary Ciliary Dyskinesia.- Pulmonary Alveolar Microlithiasis.- Cystic Fibrosis.- Pulmonary Langerhans' Cell Histiocytosis - Advances in the Understanding of a True Dendritic Cell Lung Disease.- Sarcoidosis.- Scleroderma Lung Disease.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 452 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -A Clinical Approach to Rare Lung Diseases.- Clinical Trials for Rare Lung Diseases.- Idiopathic and Familial Pulmonary Arterial Hypertension.- Lymphangioleiomyomatosis.- Autoimmune Pulmonary Alveolar Proteinosis.- Mutations in Surfactant Protein C and Interstitial Lung Disease.- Hereditary Haemorrhagic Telangiectasia.- Hermansky-Pudlak Syndrome.- Alpha-1 Antitrypsin Deficiency.- The Marfan Syndrome.- Surfactant Deficiency Disorders: SP-B and ABCA3.- Pulmonary Capillary Hemangiomatosis.- Anti-glomerular Basement Disease: Goodpasture's Syndrome.- Primary Ciliary Dyskinesia.- Pulmonary Alveolar Microlithiasis.- Cystic Fibrosis.- Pulmonary Langerhans' Cell Histiocytosis - Advances in the Understanding of a True Dendritic Cell Lung Disease.- Sarcoidosis.- Scleroderma Lung Disease.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 452 pp. Englisch.

Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Pulmonary Disease: Insights from Rare LungDisorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy-to-read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture's syndromes to Sarcoidosis and alpha one antitrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis ofPulmonary Disease: Insights from Rare Lung Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.

Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Pulmonary Disease: Insights from Rare LungDisorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy-to-read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture's syndromes to Sarcoidosis and alpha one antitrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis ofPulmonary Disease: Insights from Rare Lung Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.

Condition: New. PRINT ON DEMAND pp. 452.