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Published by Taylor & Francis Ltd, 2024
ISBN 10: 1032068426 ISBN 13: 9781032068428
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Published by Taylor & Francis Group, 2021
ISBN 10: 0367895668 ISBN 13: 9780367895662
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Published by Taylor & Francis Group, 2021
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Carsten Berndt is in the Department of Neurology, Heinrich-Heine-Universitaet Duesseldorf. He is the author or co-author of over 50 peer revidewed scholarly publications. His research has focuesd on the essential role of redox regulation in health and disea.
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Even before oxygen appeared in our athmosphere, redox reactions provided the energy for metabolic steps in the evolution of life. Redox modifications are now important in cellular functions including differentiation/development. This book compiles current knowledge regarding the roles of redox regulation in differentiation and de-differentiation.
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Carsten Berndt is in the Department of Neurology, Heinrich-Heine-Universitaet Duesseldorf. He is the author or co-author of over 50 peer revidewed scholarly publications. His research has focuesd on the essential role of redox regulation in health and disea.
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Language: English
Published by Taylor & Francis Group, 2021
ISBN 10: 0367895668 ISBN 13: 9780367895662
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Cell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox modifications are established as important regulatory events in cellular functions including differentiation and development. Redox modifications of single cysteines regulate differentiation of stem cells, formation of functioning organs, and de-differentiation such as formation of cancer cells. Current cancer therapy is based on redox events as well and regeneration often reactivates developmental pathways. Understanding differentiation and de-differentiation on a molecular level is therefore a prerequisite for the continuing development of new medical therapies. This book summarizes the roles of redox regulation in development by bringing together different concepts and comparing similarities and differences between various cell types and species. An international team of contributors presents several new aspects of redox-regulated differentiation and de-differentiation, including aspects of redox medicine.Key FeaturesProvides the first summary on this important topicReviews redox-dependent development of model organisms and single organsHighlights the redox-regulated pathways important for differentiation processesIllustrates the potential of redox medicineCombines state-of-the-art knowledge in differentiation/development, aging/longevity, and repair/regenerationWritten by leading experts in the fieldRelated TitlesAyyanathan, K., ed. Cancer Cell Signaling: Targeting Signaling Pathways Toward Therapeutic Approaches to Cancer (ISBN 978-1-77188-067-1)Clarke, M. & J. Frampton. Stem Cells: Biology and Application (ISBN 9780-8153-4511-4)Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1)Wong, E., ed. Autophagy and Signaling (ISBN 978-0-367-65772-7).