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  • Language: English

    Published by Plenum Press, New York & London, 1991

    0306439077 / 9780306439070

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    Hardcover. Condition: Fine condition. No jacket, as issued. First Printing of the First Edition. New York & London: Plenum Press, 1991. Fine condition but for previous owner's name on front endpaper. A bright, shiny, clean, square, tight copy. Sharp corners. NOT a library discard. NOT a remainder. Pages are fresh, crisp, and unmarked -- probably never read. Hardcover. First printing. Proceedings of the First Toronto-Stockholm Symposium on Perspectives in Diabetes Research, held June 28-29, 1990 in Toronto. Volume 291 in the ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY series. Illustrated with figures, diagrams, and photographs. Tables. Graphs. Bibliographical references. Index. Bound in the original glossy laminated blue and white boards. First Printing of the First Edition. Hardcover. Fine condition/No jacket, as issued. 8vo. x, 278pp.

  • Language: English

    Published by Plenum Press, 1991

    0306439077 / 9780306439070

    • Hardcover

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    Hardcover. 278pp. As new, clean, tight & bright condition.

  • Language: English

    Published by Springer, 2012

    1468459333 / 9781468459333

    • Softcover

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  • Language: English

    Published by Springer, 2012

    1461362628 / 9781461362623

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  • Language: English

    Published by Springer, 2012

    1468459333 / 9781468459333

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    Condition: New. pp. 294.

  • Language: English

    Published by Springer, 1993

    0306445638 / 9780306445637

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    Condition: New. [plenum 913].

  • Language: English

    Published by Springer, 2012

    1461362628 / 9781461362623

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    Condition: New. pp. 332.

  • Language: English

    Published by Springer, Springer, 2012

    1468459333 / 9781468459333

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    Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book has a dual purpose, to review in depth the control of fuel homeostasis in the brain and the role of the nervous system in the control of fuel deposition in the body. From the methodological point of view the emphasis is on the application of advanced technologies to assess fuel transport and brain metabolism, the role of peptides in the neuroendocrine system and the response of the brain to hypoglycemia. These technologies include positron emmission tomography, nuclear magnetic resonance, immunocytochemistry, molecular biology, autoradiography. To study fuel homeostasis in the body advanced tracer methods that include modelling are set out. From the pathophysiological point of view the emphasis is on abnormalities in stress, brain metabolism in diabetes, eating and degenerative disorders. This book contains contributions from endocrinologists, physiologists, neurologists, psychoneuroendocrinOlogists, biophysicists, biochemists and experts in nutrition. This authorship represents a unique diversity of researchers who, for the first time, cover comprehensively the interaction between the nervous system and fuel homeostasis, both in health and disease. We hope this book will be an important source of information for both researchers and practicing clinicians. Mladen Vranic Suad Efendic Charles Hollenberg v ACKNOWLEDGEMENTS The Symposium from which this volume arose (University of Toronto, June 27-28, 1990) was the first Toronto-Stockholm symposium on Perspectives in Diabetes Research. These Symposia are organized triennially by the Banting and Best Diabetes Centre, University of Toronto and the Department of Endocrinology, Karolinska Institute, Stockholm.

  • Language: English

    Published by Springer, Springer, 2012

    1461362628 / 9781461362623

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    Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM) has attracted the interest of our group during the last three decades. As early as 1969, a Nobel Symposium dealing with this topic was organized in Stockholm. This was followed in 1987 by a Nobel Conference devoted to the same subject. The main purpose of these meetings was to bring together the most distinguished scientists from all over the world and present theories on molecular and genetic mechanisms responsible for the development of glucose intolerance in NIDDM. This idea was followed also in the present symposium, 'New Concepts in the Pathogenesis of NIDDM,' organized with diabetologists from Toronto in Canada. Our purpose is to biannually organize international meetings covering important aspects of dia betes research, hoping that this type of interaction may result in new concepts and treat ment alternatives. For us, participating in this symposium in September 1992, the meeting in Stockholm was very stimulating and innovative. It is a special pleasure that almost all invited lecturers submitted manuscripts. Thus, the publication of the proceedings of the symposium makes it possible for all interested in diabetes research to share new ideas and findings presented at the meeting. Claes-G6ran Ostenson Suad Efendic Mladen V ranic v CONTENTS REGULATION OF INSULIN SECRETION Impaired Glucose-Induced Insulin Secretion: Studies in Animal Models with Spontaneous NIDDM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C. -G. Ostenson, A. Khan, and S. Efendic Perturbation ofIslet Metabolism and Insulin Release in NIDDM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 WJ.Malaisse 2 Regulation of Cytoplasmic Free Ca+ in Insulin-Secreting Cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

  • Language: English

    Published by Springer, 1993

    0306445638 / 9780306445637

    • Hardcover

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  • Language: English

    Published by Springer, 1993

    0306445638 / 9780306445637

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  • Language: English

    Published by Springer, 1993

    0306445638 / 9780306445637

    • Hardcover

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    Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Regulation of Insulin Secretion.- Impaired Glucose-Induced Insulin Secretion: Studies in Animal Models with Spontaneous NIDDM.- Perturbation of Islet Metabolism and Insulin Release in NIDDM.- Regulation of Cytoplasmic Free Ca2+ in Insulin-Secreting Cells.- The ß-Cell Sulfonylurea Receptor.- Insulin, Insulin Receptors and Glucose Transporters.- Regulation of Glucose Transporters and the Na/K-ATPase by Insulin in Skeletal Muscle.- Insulin Receptor: Aspects of Its Structure and function.- The Diabetogenes Concept of NIDDM.- Molecular Genetics of NIDDM and the Genes for Insulin and Insulin Receptor.- Autoregulation of Glucose Transport: Effects of Glucose on Glucose Transporter Expression and Cellular Location in Muscle.- Insulin Action in NIDDM.- Insulin Resistance and the Pathogenesis of Non-Insulin Dependent Diabetes Mellitus: Cellular and Molecular Mechanisms.- Indirect Effects of Insulin in Regulating Glucose Fluxes.- The Insulin-Antagonistic Effect of the Counterregulatory Hormones - Clinical and Mechanistic Aspects.- On Insulin Action in Vivo: The Single Gateway Hypothesis.- Gluconeogenesis.- Acute Hormonal Regulation of Gluconeogenesis in the Conscious Dog.- Estimating Gluconeogenic Rates in NIDDM.- Glucose Metabolism during Physical Exercise in Patients with Noninsulin-Dependent (Type II) Diabetes.- Substrates and the Regulation of Hepatic Glycogen Metabolism.- Gluconeogenesis in Type 2 Diabetes.- Obesity, Lipoproteins, Atherogenesis, and NIDDM.- Regulation of Adipose Tissue Lipolysis, Importance for the Metabolic Syndrome.- Cellular and Molecular Factors in Adipose Tissue Growth and Obesity.- Regional Obesity and NIDDM.- Hyperinsulinemia and VLDL Kinetics.- Hyperinsulinism and Dyslipidemias as Coronary Heart Disease Risk Factors in NIDDM.- Potential Impact of New Concepts In NIDDM on Delivery of Care to Diabetic Populations.- A Paradigm to Link Clinical Research to Clinical Practice: The Challenge in Non-Insulin Dependent Diabetes Mellitus.

  • Language: English

    Published by Springer, 2012

    1468459333 / 9781468459333

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  • Language: English

    Published by Plenum Pub Corp, 1993

    0306445638 / 9780306445637

    • Hardcover

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    Hardcover. Condition: Brand New. 332 pages. 10.25x7.00x0.75 inches. In Stock.

  • Language: English

    Published by Springer, Berlin, 1993

    0306445638 / 9780306445637

    • Hardcover

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    Gebunden. Condition: New. KlappentextTwo dozen papers present theories on the molecular and genetic mechanisms responsible for the development of glucose intolerance in non-insulin-dependent diabetes mellitus. They cover the regulation of insulin secretion insul.

  • Language: English

    Published by Springer, 2012

    1468459333 / 9781468459333

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  • Language: English

    Published by Springer, 2012

    1461362628 / 9781461362623

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  • Language: English

    Published by Springer, Springer Mär 2012, 2012

    1468459333 / 9781468459333

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    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book has a dual purpose, to review in depth the control of fuel homeostasis in the brain and the role of the nervous system in the control of fuel deposition in the body. From the methodological point of view the emphasis is on the application of advanced technologies to assess fuel transport and brain metabolism, the role of peptides in the neuroendocrine system and the response of the brain to hypoglycemia. These technologies include positron emmission tomography, nuclear magnetic resonance, immunocytochemistry, molecular biology, autoradiography. To study fuel homeostasis in the body advanced tracer methods that include modelling are set out. From the pathophysiological point of view the emphasis is on abnormalities in stress, brain metabolism in diabetes, eating and degenerative disorders. This book contains contributions from endocrinologists, physiologists, neurologists, psychoneuroendocrinOlogists, biophysicists, biochemists and experts in nutrition. This authorship represents a unique diversity of researchers who, for the first time, cover comprehensively the interaction between the nervous system and fuel homeostasis, both in health and disease. We hope this book will be an important source of information for both researchers and practicing clinicians. Mladen Vranic Suad Efendic Charles Hollenberg v ACKNOWLEDGEMENTS The Symposium from which this volume arose (University of Toronto, June 27-28, 1990) was the first Toronto-Stockholm symposium on Perspectives in Diabetes Research. These Symposia are organized triennially by the Banting and Best Diabetes Centre, University of Toronto and the Department of Endocrinology, Karolinska Institute, Stockholm. 292 pp. Englisch.

  • Language: English

    Published by Springer, Springer Okt 2012, 2012

    1461362628 / 9781461362623

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    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM) has attracted the interest of our group during the last three decades. As early as 1969, a Nobel Symposium dealing with this topic was organized in Stockholm. This was followed in 1987 by a Nobel Conference devoted to the same subject. The main purpose of these meetings was to bring together the most distinguished scientists from all over the world and present theories on molecular and genetic mechanisms responsible for the development of glucose intolerance in NIDDM. This idea was followed also in the present symposium, 'New Concepts in the Pathogenesis of NIDDM,' organized with diabetologists from Toronto in Canada. Our purpose is to biannually organize international meetings covering important aspects of dia betes research, hoping that this type of interaction may result in new concepts and treat ment alternatives. For us, participating in this symposium in September 1992, the meeting in Stockholm was very stimulating and innovative. It is a special pleasure that almost all invited lecturers submitted manuscripts. Thus, the publication of the proceedings of the symposium makes it possible for all interested in diabetes research to share new ideas and findings presented at the meeting. Claes-G6ran Ostenson Suad Efendic Mladen V ranic v CONTENTS REGULATION OF INSULIN SECRETION Impaired Glucose-Induced Insulin Secretion: Studies in Animal Models with Spontaneous NIDDM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C. -G. Ostenson, A. Khan, and S. Efendic Perturbation ofIslet Metabolism and Insulin Release in NIDDM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 WJ.Malaisse 2 Regulation of Cytoplasmic Free Ca+ in Insulin-Secreting Cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332 pp. Englisch.

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    Condition: New. Print on Demand pp. 294 66:B&W 7 x 10 in or 254 x 178 mm Perfect Bound on White w/Gloss Lam.

  • Language: English

    Published by Springer-Verlag New York Inc., 2012

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    Published by Springer-Verlag New York Inc., 2012

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    Condition: New. PRINT ON DEMAND pp. 294.

  • Language: English

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    Condition: New. Print on Demand pp. 332 66:B&W 7 x 10 in or 254 x 178 mm Perfect Bound on White w/Gloss Lam.

  • Language: English

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    Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proceedings of the First Toronto-Stockholm Symposium on Perspectives in Diabetes Research, held in Toronto, Ontario, Canada, June 28--29, 1990 This book has a dual purpose, to review in depth the control of fuel homeostasis in the brain and the ro.

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    Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM) has attracted the interest of our group during the last three decades. As early as 1969, a Nobel Symposium dealing with this topic was organized in Stockholm. This was followed in 1987 by a.

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    Condition: New. PRINT ON DEMAND pp. 332.

  • Language: English

    Published by SPRINGER NATURE Sep 1993, 1993

    0306445638 / 9780306445637

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    Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Regulation of Insulin Secretion.- Impaired Glucose-Induced Insulin Secretion: Studies in Animal Models with Spontaneous NIDDM.- Perturbation of Islet Metabolism and Insulin Release in NIDDM.- Regulation of Cytoplasmic Free Ca2+ in Insulin-Secreting Cells.- The ß-Cell Sulfonylurea Receptor.- Insulin, Insulin Receptors and Glucose Transporters.- Regulation of Glucose Transporters and the Na/K-ATPase by Insulin in Skeletal Muscle.- Insulin Receptor: Aspects of Its Structure and function.- The Diabetogenes Concept of NIDDM.- Molecular Genetics of NIDDM and the Genes for Insulin and Insulin Receptor.- Autoregulation of Glucose Transport: Effects of Glucose on Glucose Transporter Expression and Cellular Location in Muscle.- Insulin Action in NIDDM.- Insulin Resistance and the Pathogenesis of Non-Insulin Dependent Diabetes Mellitus: Cellular and Molecular Mechanisms.- Indirect Effects of Insulin in Regulating Glucose Fluxes.- The Insulin-Antagonistic Effect of the Counterregulatory Hormones - Clinical and Mechanistic Aspects.- On Insulin Action in Vivo: The Single Gateway Hypothesis.- Gluconeogenesis.- Acute Hormonal Regulation of Gluconeogenesis in the Conscious Dog.- Estimating Gluconeogenic Rates in NIDDM.- Glucose Metabolism during Physical Exercise in Patients with Noninsulin-Dependent (Type II) Diabetes.- Substrates and the Regulation of Hepatic Glycogen Metabolism.- Gluconeogenesis in Type 2 Diabetes.- Obesity, Lipoproteins, Atherogenesis, and NIDDM.- Regulation of Adipose Tissue Lipolysis, Importance for the Metabolic Syndrome.- Cellular and Molecular Factors in Adipose Tissue Growth and Obesity.- Regional Obesity and NIDDM.- Hyperinsulinemia and VLDL Kinetics.- Hyperinsulinism and Dyslipidemias as Coronary Heart Disease Risk Factors in NIDDM.- Potential Impact of New Concepts In NIDDM on Delivery of Care to Diabetic Populations.- A Paradigm to Link Clinical Research to Clinical Practice: The Challenge in Non-Insulin Dependent Diabetes Mellitus. 332 pp. Englisch.

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    1461362628 / 9781461362623

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    Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM) has attracted the interest of our group during the last three decades. As early as 1969, a Nobel Symposium dealing with this topic was organized in Stockholm. This was followed in 1987 by a Nobel Conference devoted to the same subject. The main purpose of these meetings was to bring together the most distinguished scientists from all over the world and present theories on molecular and genetic mechanisms responsible for the development of glucose intolerance in NIDDM. This idea was followed also in the present symposium, 'New Concepts in the Pathogenesis of NIDDM,' organized with diabetologists from Toronto in Canada. Our purpose is to biannually organize international meetings covering important aspects of dia betes research, hoping that this type of interaction may result in new concepts and treat ment alternatives. For us, participating in this symposium in September 1992, the meeting in Stockholm was very stimulating and innovative. It is a special pleasure that almost all invited lecturers submitted manuscripts. Thus, the publication of the proceedings of the symposium makes it possible for all interested in diabetes research to share new ideas and findings presented at the meeting. Claes-G6ran Ostenson Suad Efendic Mladen V ranic v CONTENTS REGULATION OF INSULIN SECRETION Impaired Glucose-Induced Insulin Secretion: Studies in Animal Models with Spontaneous NIDDM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C. -G. Ostenson, A. Khan, and S. Efendic Perturbation ofIslet Metabolism and Insulin Release in NIDDM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 WJ.Malaisse 2 Regulation of Cytoplasmic Free Ca+ in Insulin-Secreting Cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 332 pp. Englisch.

  • Language: English

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    1468459333 / 9781468459333

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    Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book has a dual purpose, to review in depth the control of fuel homeostasis in the brain and the role of the nervous system in the control of fuel deposition in the body. From the methodological point of view the emphasis is on the application of advanced technologies to assess fuel transport and brain metabolism, the role of peptides in the neuroendocrine system and the response of the brain to hypoglycemia. These technologies include positron emmission tomography, nuclear magnetic resonance, immunocytochemistry, molecular biology, autoradiography. To study fuel homeostasis in the body advanced tracer methods that include modelling are set out. From the pathophysiological point of view the emphasis is on abnormalities in stress, brain metabolism in diabetes, eating and degenerative disorders. This book contains contributions from endocrinologists, physiologists, neurologists, psychoneuroendocrinOlogists, biophysicists, biochemists and experts in nutrition. This authorship represents a unique diversity of researchers who, for the first time, cover comprehensively the interaction between the nervous system and fuel homeostasis, both in health and disease. We hope this book will be an important source of information for both researchers and practicing clinicians. Mladen Vranic Suad Efendic Charles Hollenberg v ACKNOWLEDGEMENTS The Symposium from which this volume arose (University of Toronto, June 27-28, 1990) was the first Toronto-Stockholm symposium on Perspectives in Diabetes Research. These Symposia are organized triennially by the Banting and Best Diabetes Centre, University of Toronto and the Department of Endocrinology, Karolinska Institute, Stockholm.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 292 pp. Englisch.