Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: Majestic Books, Hounslow, United Kingdom
Condition: New. pp. xvii + 397 Illus.
Language: English
Published by Royal Society of Chemistry RSC, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: Books Puddle, New York, NY, U.S.A.
Condition: New. pp. xvii + 397.
Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: Biblios, Frankfurt am main, HESSE, Germany
Condition: New. pp. xvii + 397.
Condition: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,900grams, ISBN:9780854042722.
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Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Condition: New.
Language: English
Published by Royal Society of Chemistry, GB, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: Rarewaves USA, OSWEGO, IL, U.S.A.
Hardback. Condition: New. The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid 1980s and a vast array of such structures has now been determined, but surprising and novel structures still appear quite frequently. High-resolution structures of protein-RNA complexes were relatively rare until the last decade. Propelled by advances in technology as well as the realization of RNA's importance to biology, the number of example structures has ballooned in recent years. New insights are now being gained from comparative studies only recently made possible due to the size of the database, as well as from careful biochemical and biophysical studies. As a result of the explosion of research in this area, it is no longer possible to write a comprehensive review. Instead, current review articles tend to focus on particular subtopics of interest. This makes it difficult for newcomers to the field to attain a solid understanding of the basics. One goal of this book is therefore to provide in-depth discussions of the fundamental principles of protein-nucleic acid interactions as well as to illustrate those fundamentals with up-to-date and fascinating examples for those who already possess some familiarity with the field. The book also aims to bridge the gap between the DNA- and the RNA- views of nucleic acid - protein recognition, which are often treated as separate fields. However, this is a false dichotomy because protein - DNA and protein - RNA interactions share many general principles. This book therefore includes relevant examples from both sides, and frames discussions of the fundamentals in terms that are relevant to both. The monograph approaches the study of protein-nucleic acid interactions in two distinctive ways. First, DNA-protein and RNA-protein interactions are presented together. Second, the first half of the book develops the principles of protein-nucleic acid recognition, whereas the second half applies these to more specialized topics. Both halves are illustrated with important real life examples. The first half of the book develops fundamental principles necessary to understand function. An introductory chapter by the editors reviews the basics of nucleic acid structure. Jen-Jacobsen and Jacobsen discuss how solvent interactions play an important role in recognition, illustrated with extensive thermodynamic data on restriction enzymes. Marmorstein and Hong introduce the zoology of the DNA binding domains found in transcription factors, and describe the combinational recognition strategies used by many multiprotein eukaryotic complexes. Two chapters discuss indirect readout of DNA sequence in detail: Berman and Lawson explain the basic principles and illustrate them with in-depth studies of CAP, while in their chapter on DNA bending and compaction Johnson, Stella and Heiss highlight the intrinsic connections between D.
Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
HRD. Condition: New. New Book. Shipped from UK. Established seller since 2000.
Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
HRD. Condition: New. New Book. Shipped from UK. Established seller since 2000.
Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
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Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
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Language: English
Published by Royal Society of Chemistry, GB, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: Rarewaves USA United, OSWEGO, IL, U.S.A.
Hardback. Condition: New. The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid 1980s and a vast array of such structures has now been determined, but surprising and novel structures still appear quite frequently. High-resolution structures of protein-RNA complexes were relatively rare until the last decade. Propelled by advances in technology as well as the realization of RNA's importance to biology, the number of example structures has ballooned in recent years. New insights are now being gained from comparative studies only recently made possible due to the size of the database, as well as from careful biochemical and biophysical studies. As a result of the explosion of research in this area, it is no longer possible to write a comprehensive review. Instead, current review articles tend to focus on particular subtopics of interest. This makes it difficult for newcomers to the field to attain a solid understanding of the basics. One goal of this book is therefore to provide in-depth discussions of the fundamental principles of protein-nucleic acid interactions as well as to illustrate those fundamentals with up-to-date and fascinating examples for those who already possess some familiarity with the field. The book also aims to bridge the gap between the DNA- and the RNA- views of nucleic acid - protein recognition, which are often treated as separate fields. However, this is a false dichotomy because protein - DNA and protein - RNA interactions share many general principles. This book therefore includes relevant examples from both sides, and frames discussions of the fundamentals in terms that are relevant to both. The monograph approaches the study of protein-nucleic acid interactions in two distinctive ways. First, DNA-protein and RNA-protein interactions are presented together. Second, the first half of the book develops the principles of protein-nucleic acid recognition, whereas the second half applies these to more specialized topics. Both halves are illustrated with important real life examples. The first half of the book develops fundamental principles necessary to understand function. An introductory chapter by the editors reviews the basics of nucleic acid structure. Jen-Jacobsen and Jacobsen discuss how solvent interactions play an important role in recognition, illustrated with extensive thermodynamic data on restriction enzymes. Marmorstein and Hong introduce the zoology of the DNA binding domains found in transcription factors, and describe the combinational recognition strategies used by many multiprotein eukaryotic complexes. Two chapters discuss indirect readout of DNA sequence in detail: Berman and Lawson explain the basic principles and illustrate them with in-depth studies of CAP, while in their chapter on DNA bending and compaction Johnson, Stella and Heiss highlight the intrinsic connections between D.
Language: English
Published by ROYAL SOCIETY OF CHEMISTRY, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: moluna, Greven, Germany
Condition: New. Written by a team of experts, this book bridges the gap between the DNA- and RNA- views of protein-nucleic acid recognition which are often treated as separate fields.Über den AutorrnrnDr Rice is an associate professor in the Department.
Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
£ 210.99
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Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: THE SAINT BOOKSTORE, Southport, United Kingdom
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Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
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Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Condition: As New. Unread book in perfect condition.
Language: English
Published by Royal Society of Chemistry, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: Revaluation Books, Exeter, United Kingdom
Hardcover. Condition: Brand New. 1st edition. 397 pages. 9.25x6.50x1.25 inches. In Stock.
Language: English
Published by RSC Publishing Apr 2008, 2008
ISBN 10: 0854042725 ISBN 13: 9780854042722
Seller: AHA-BUCH GmbH, Einbeck, Germany
Buch. Condition: Neu. Neuware - The structural biology of protein - nucleic acid interactions is in some ways a mature field and in others in its infancy. Propelled by advances in technology as well as the realization of RNA's importance to biology, the number of example structures has ballooned in recent years. As a result of the explosion of research in this area, it is no longer possible to write a comprehensive review which makes it difficult for newcomers to the field to attain a solid understanding of the basics. One goal of this book is therefore to provide in-depth discussions of the fundamental principles of protein-nucleic interactions as well as to illustrate those fundamentals with up-to-date and fascinating examples for those who already possess some familiarity with the field. The book also emphasises the impact of structural biology on understanding how proteins interact with nucleic acids and it is intended for advanced students and established scientists wishing to broaden their horizons. A team of experts have been assembled to write the individual chapters of this book. The beginning chapters focus on more fundamental aspects of protein-nucleic acid interactions, such as thermodynamics and recognition strategies, while later chapters highlight more specialized topics in RNA and DNA metabolism, such as chaperones, modifying enzymes, topoisomerases, recombinases, and nucleases. Since it is impossible to cover all aspects of this rapidly expanding field, the editors have chosen to highlight a few topics that are fascinating in their own right while also providing a broad range of examples to underscore the basic principles.