Bhati Lokesh Kumar (11 results)

Taschenbuch. Condition: Neu. Neuware -The study demonstrated the possibility of significantly improving the dissolution performance of MX by simultaneous complexation with cyclodextrin. The importance of proper selection of the most suitable counter ion to adequately improve the cyclodextrin - complexation efficiency has been pointed out. PVP showed a synergistic effect when used in combination with HP¿-CD. Phase solubility experiments demonstrated that the ternary system with PVP (pH 5.8) exhibited a stability constant 12.9 times greater than the binary complex. The drug solubility in the presence of 50mM HP¿-CD was about 6.23 times higher than that in the binary system. Results confirmed that the strong increase in the drug solubility shown by HP¿-CD ternary system with PVP. Solid state demonstrated that freeze drying technique was suitable for obtaining solid homogeneous equimolar MX-HP¿-CD-PVP complexes. These systems could be useful for formulating fast-dissolving drug solid dosage form able to assure rapid onset of analgesic action and improved bioavailability.Books on Demand GmbH, Überseering 33, 22297 Hamburg 120 pp. Englisch.

Taschenbuch. Condition: Neu. Enhancement of complexation of drug: binary and ternary mixtures | Bhati et al. enhancement of complexation | Lokesh Kumar Bhati (u. a.) | Taschenbuch | 120 S. | Englisch | 2012 | LAP LAMBERT Academic Publishing | EAN 9783848493906 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.

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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study demonstrated the possibility of significantly improving the dissolution performance of MX by simultaneous complexation with cyclodextrin. The importance of proper selection of the most suitable counter ion to adequately improve the cyclodextrin - complexation efficiency has been pointed out. PVP showed a synergistic effect when used in combination with HP -CD. Phase solubility experiments demonstrated that the ternary system with PVP (pH 5.8) exhibited a stability constant 12.9 times greater than the binary complex. The drug solubility in the presence of 50mM HP -CD was about 6.23 times higher than that in the binary system. Results confirmed that the strong increase in the drug solubility shown by HP -CD ternary system with PVP. Solid state demonstrated that freeze drying technique was suitable for obtaining solid homogeneous equimolar MX-HP -CD-PVP complexes. These systems could be useful for formulating fast-dissolving drug solid dosage form able to assure rapid onset of analgesic action and improved bioavailability. 120 pp. Englisch.

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Bhati Lokesh KumarLokesh bhati is presently a research scientist in mankind research laboratory, gurgaon, India. He is presently the reviewer of many indexed journals. He has many publications in national and international journals.H.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The method has also been developed for dissolution of antidiabetic drugs. Initially the solubility was determined in different dissolution media. The dissolution study of drugs was performed in 7.8 pH phosphate buffer in which these two drugs shows highest solubility. The dissolution was performed in pH 2.0 medium. The dissolution study was performed using Paddle with sinkers at 75 rpm. The amount of drugs were estimated. 148 pp. Englisch.

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Bhati Lokesh KumarLokesh bhati is presently a research scientist in mankind research laboratory, gurgaon, India. He is presently the reviewer of many indexed journals. He has many publications in national and international journals.H.

Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The study demonstrated the possibility of significantly improving the dissolution performance of MX by simultaneous complexation with cyclodextrin. The importance of proper selection of the most suitable counter ion to adequately improve the cyclodextrin - complexation efficiency has been pointed out. PVP showed a synergistic effect when used in combination with HP -CD. Phase solubility experiments demonstrated that the ternary system with PVP (pH 5.8) exhibited a stability constant 12.9 times greater than the binary complex. The drug solubility in the presence of 50mM HP -CD was about 6.23 times higher than that in the binary system. Results confirmed that the strong increase in the drug solubility shown by HP -CD ternary system with PVP. Solid state demonstrated that freeze drying technique was suitable for obtaining solid homogeneous equimolar MX-HP -CD-PVP complexes. These systems could be useful for formulating fast-dissolving drug solid dosage form able to assure rapid onset of analgesic action and improved bioavailability.

Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The method has also been developed for dissolution of antidiabetic drugs. Initially the solubility was determined in different dissolution media. The dissolution study of drugs was performed in 7.8 pH phosphate buffer in which these two drugs shows highest solubility. The dissolution was performed in pH 2.0 medium. The dissolution study was performed using Paddle with sinkers at 75 rpm. The amount of drugs were estimated.

Taschenbuch. Condition: Neu. Analytical Method Development and its validation | Method Development and its validation | Lokesh Kumar Bhati (u. a.) | Taschenbuch | 148 S. | Englisch | 2012 | LAP LAMBERT Academic Publishing | EAN 9783848486489 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu Print on Demand.

Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The method has also been developed for dissolution of antidiabetic drugs. Initially the solubility was determined in different dissolution media. The dissolution study of drugs was performed in 7.8 pH phosphate buffer in which these two drugs shows highest solubility. The dissolution was performed in pH 2.0 medium. The dissolution study was performed using Paddle with sinkers at 75 rpm. The amount of drugs were estimated.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 148 pp. Englisch.