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Advancing Development of Synthetic Gene Regulators. With the Power of High-Throughput Sequencing in Chemical Biology. By Anandhakumar Chandran.
Book 343 of 797: Springer ThesesLanguage: English
Published by Singapore, Springer Singapore : Imprint: Springer., 2018
ISBN 10: 9811065462 ISBN 13: 9789811065460
Seller: Universitätsbuchhandlung Herta Hold GmbH, Berlin, Germany
Association Member: GIAQ ILAB VDA
Seller rating 5 out of 5 stars
First Edition
1st ed. 2018. XV, 114 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Springer Theses, Recognizing Outstanding Ph.D. Research. Sprache: Englisch.
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Advancing Development of Synthetic Gene Regulators. With the Power of High-Throughput Sequencing in Chemical Biology.
Book 343 of 797: Springer ThesesLanguage: English
Published by Singapore, Springer., 2018
ISBN 10: 9811348995 ISBN 13: 9789811348990
Seller: Universitätsbuchhandlung Herta Hold GmbH, Berlin, Germany
Association Member: GIAQ ILAB VDA
Seller rating 5 out of 5 stars
XV, 114 p. Softcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Springer Theses. Recognizing Outstanding Ph.D. Research. Sprache: Englisch.
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Advancing Development of Synthetic Gene Regulators: With the Power of High-Throughput Sequencing in Chemical Biology (Springer Theses)
Book 343 of 797: Springer ThesesSeller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 92.99
£ 11.98 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
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Advancing Development of Synthetic Gene Regulators: With the Power of High-Throughput Sequencing in Chemical Biology (Springer Theses)
Book 343 of 797: Springer ThesesSeller: Ria Christie Collections, Uxbridge, United Kingdom
Seller rating 5 out of 5 stars
£ 94.30
£ 11.98 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: New. In.
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Condition: New. Softcover reprint of the original 1st ed. 2018 edition NO-PA16APR2015-KAP.
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Advancing Development of Synthetic Gene Regulators: With the Power of High-Throughput Sequencing in Chemical Biology
Book 343 of 797: Springer ThesesSeller: Kennys Bookshop and Art Galleries Ltd., Galway, GY, Ireland
Seller rating 5 out of 5 stars
Condition: New. 2019. Paperback. . . . . .
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Advanced Computational Intelligence Techniques for Engineers
Language: English
Published by Chapman and Hall/CRC, 2025
ISBN 10: 1032873426 ISBN 13: 9781032873428
Condition: As New. Unread book in perfect condition.
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Paperback. Condition: Brand New. reprint edition. 132 pages. 9.25x6.10x0.30 inches. In Stock.
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Hardcover. Condition: Brand New. 129 pages. 9.25x6.10x0.59 inches. In Stock.
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Advanced Computational Intelligence Techniques for Engineers
Language: English
Published by Chapman and Hall/CRC, 2025
ISBN 10: 1032873426 ISBN 13: 9781032873428
Condition: New.
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Advanced Computational Intelligence Techniques for Engineers
Language: English
Published by Chapman and Hall/CRC, 2025
ISBN 10: 1032873426 ISBN 13: 9781032873428
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
Condition: As New. Unread book in perfect condition.
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Condition: New. 2019. Paperback. . . . . . Books ship from the US and Ireland.
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Advancing Development of Synthetic Gene Regulators
Book 343 of 797: Springer ThesesLanguage: English
Published by Springer Nature Singapore, Springer Nature Singapore Jan 2019, 2019
ISBN 10: 9811348995 ISBN 13: 9789811348990
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. Neuware -This book focuses on an ¿outside the box¿ notion by utilizing the powerful applications of next-generation sequencing (NGS) technologies in the interface of chemistry and biology. In personalized medicine, developing small molecules targeting a specific genomic sequence is an attractive goal. N-methylpyrrole (P)¿N-methylimidazole (I) polyamides (PIPs) are a class of small molecule that can bind to the DNA minor groove. First, a cost-effective NGS (ion torrent platform)-based Bind-n-Seq was developed to identify the binding specificity of PIP conjugates in a randomized DNA library. Their biological influences rely primarily on selective DNA binding affinity, so it is important to analyze their genome-wide binding preferences. However, it is demanding to enrich specifically the small-molecule-bound DNA without chemical cross-linking or covalent binding in chromatinized genomes. Herein is described a method that was developed using high-throughput sequencing to map the differential binding sites and relative enriched regions of non-cross-linked SAHA-PIPs throughout the complex human genome. SAHA-PIPs binding motifs were identified and the genome-level mapping of SAHA-PIPs-enriched regions provided evidence for the differential activation of the gene network. A method using high-throughput sequencing to map the binding sites and relative enriched regions of alkylating PIP throughout the human genome was also developed. The genome-level mapping of alkylating the PIP-enriched region and the binding sites on the human genome identifies significant genomic targets of breast cancer. It is anticipated that this pioneering low-cost, high through-put investigation at the sequence-specific level will be helpful in understanding the binding specificity of various DNA-binding small molecules, which in turn will be beneficial for the development of small-molecule-based drugs targeting a genome-level sequence.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 132 pp. Englisch.
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Advancing Development of Synthetic Gene Regulators : With the Power of High-Throughput Sequencing in Chemical Biology
Book 343 of 797: Springer ThesesLanguage: English
Published by Springer Nature Singapore, Springer Nature Singapore, 2019
ISBN 10: 9811348995 ISBN 13: 9789811348990
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book focuses on an 'outside the box' notion by utilizing the powerful applications of next-generation sequencing (NGS) technologies in the interface of chemistry and biology. In personalized medicine, developing small molecules targeting a specific genomic sequence is an attractive goal. N-methylpyrrole (P)-N-methylimidazole (I) polyamides (PIPs) are a class of small molecule that can bind to the DNA minor groove. First, a cost-effective NGS (ion torrent platform)-based Bind-n-Seq was developed to identify the binding specificity of PIP conjugates in a randomized DNA library. Their biological influences rely primarily on selective DNA binding affinity, so it is important to analyze their genome-wide binding preferences. However, it is demanding to enrich specifically the small-molecule-bound DNA without chemical cross-linking or covalent binding in chromatinized genomes. Herein is described a method that was developed using high-throughput sequencing to map the differential binding sites and relative enriched regions of non-cross-linked SAHA-PIPs throughout the complex human genome. SAHA-PIPs binding motifs were identified and the genome-level mapping of SAHA-PIPs-enriched regions provided evidence for the differential activation of the gene network. A method using high-throughput sequencing to map the binding sites and relative enriched regions of alkylating PIP throughout the human genome was also developed. The genome-level mapping of alkylating the PIP-enriched region and the binding sites on the human genome identifies significant genomic targets of breast cancer. It is anticipated that this pioneering low-cost, high through-put investigation at the sequence-specific level will be helpful in understanding the binding specificity of various DNA-binding small molecules, which in turn will be beneficial for the development of small-molecule-based drugs targeting a genome-level sequence.
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Advancing Development of Synthetic Gene Regulators : With the Power of High-Throughput Sequencing in Chemical Biology
Book 343 of 797: Springer ThesesLanguage: English
Published by Springer Nature Singapore, 2017
ISBN 10: 9811065462 ISBN 13: 9789811065460
Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book focuses on an 'outside the box' notion by utilizing the powerful applications of next-generation sequencing (NGS) technologies in the interface of chemistry and biology. In personalized medicine, developing small molecules targeting a specific genomic sequence is an attractive goal. N-methylpyrrole (P)-N-methylimidazole (I) polyamides (PIPs) are a class of small molecule that can bind to the DNA minor groove. First, a cost-effective NGS (ion torrent platform)-based Bind-n-Seq was developed to identify the binding specificity of PIP conjugates in a randomized DNA library. Their biological influences rely primarily on selective DNA binding affinity, so it is important to analyze their genome-wide binding preferences. However, it is demanding to enrich specifically the small-molecule-bound DNA without chemical cross-linking or covalent binding in chromatinized genomes. Herein is described a method that was developed using high-throughput sequencing to map the differential binding sites and relative enriched regions of non-cross-linked SAHA-PIPs throughout the complex human genome. SAHA-PIPs binding motifs were identified and the genome-level mapping of SAHA-PIPs-enriched regions provided evidence for the differential activation of the gene network. A method using high-throughput sequencing to map the binding sites and relative enriched regions of alkylating PIP throughout the human genome was also developed. The genome-level mapping of alkylating the PIP-enriched region and the binding sites on the human genome identifies significant genomic targets of breast cancer. It is anticipated that this pioneering low-cost, high through-put investigation at the sequence-specific level will be helpful in understanding the binding specificity of various DNA-binding small molecules, which in turn will be beneficial for the development of small-molecule-based drugs targeting a genome-level sequence.
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Condition: New. 1st edition NO-PA16APR2015-KAP.
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Hardcover. Condition: Brand New. 310 pages. 9.00x6.00x1.00 inches. In Stock.
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Advanced Computational Intelligence Techniques for Engineers
Language: English
Published by Chapman and Hall/CRC, 2025
ISBN 10: 1032873426 ISBN 13: 9781032873428
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
Condition: New.
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Sensor Technologies for Food Quality and Safety (Detection Science Series, Volume 29)
Language: English
Published by Royal Society of Chemistry, 2025
ISBN 10: 183767065X ISBN 13: 9781837670659
Condition: New. 1st edition NO-PA16APR2015-KAP.
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Sensor Technologies for Food Quality and Safety (Detection Science Series, Volume 29)
Language: English
Published by Royal Society of Chemistry, 2025
ISBN 10: 183767065X ISBN 13: 9781837670659
Condition: New.
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Emerging Phytosynthesized Nanomaterials for Biomedical Applications
Book 387 of 393: Micro and Nano TechnologiesSeller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
£ 172.85
£ 15 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: New.
