Understanding Amyotrophic Lateral Sclerosis: Causes and Management : Understanding Causes, Managing Care,and Exploring Treatment Advances inAmyotrophic Lateral Sclerosis

Language: English

Published by LAP LAMBERT Academic Publishing, 2025

6208420326 / 9786208420321

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  • New
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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Softcover

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nach der Bestellung gedruckt Neuware - Printed after ordering - Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder marked by muscle weakness, atrophy, fasciculations, and spasticity due to motor neuron degeneration. Symptoms progress from focal weakness to difficulties in speaking, swallowing, and breathing, with eventual paralysis. The disease arises from mechanisms such as disrupted RNA metabolism (e.g., TDP-43 and FUS mutations), cytoskeletal and axonal transport defects (e.g., PFN1, TUBA4A mutations), excitotoxicity, and oxidative stress. While incurable, treatments like Riluzole and Edaravone can modestly slow progression, and supportive care-such as non-invasive ventilation, feeding tubes, and physical therapy-helps manage symptoms. Emerging therapies, including gene and RNA-targeted approaches, hold promise for the future.

Seller Inventory # 9786208420321

Title
Understanding Amyotrophic Lateral Sclerosis: Causes and Management : Understanding Causes, Managing Care,and Exploring Treatment Advances inAmyotrophic Lateral Sclerosis
Author
Mona El-Banna
Publisher
LAP LAMBERT Academic Publishing
Publication year
2025
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6208420326
ISBN 13
9786208420321
Item weight
107 grams
Dimensions
220x150x5 mm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

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