Normal and Binding Mode Analysis of Breast Cancer Resistance Protein : Structural Bioinformatics of BCRP
Language: English
Published by LAP Lambert Academic Publishing, 2012
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 62.73
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Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - Breast Cancer Resistance Protein (BCRP) is a membrane-associated protein and a member of the the super family of ATP-binding cassette (ABC) transporters known to confer multidrug resistance (MDR) to a number of important anticancer agent and play an important function in governing drug absorption. This book deals about the development of homology model of BCRP and its correspondence with experimentally known topology. This study also helped to understand the protein dynamics of BCRP through coarse-grained normal mode analysis. Structural analysis of substrate specificity bestowed by specific amino acids and its interaction with various synthetic and natural compounds provided clues of developing an efficient inhibitor.
Seller Inventory # 9783659153129
- Title
- Normal and Binding Mode Analysis of Breast Cancer Resistance Protein : Structural Bioinformatics of BCRP
- Author
- Prasanth Kumar
- Publisher
- LAP Lambert Academic Publishing
- Publication year
- 2012
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3659153125
- ISBN 13
- 9783659153129
- Item weight
- 171 grams
- Dimensions
- 220x176x33 mm
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