Formulation and Evaluation of Floating Tablets of Quetiapine Fumarate

Language: English

Published by LAP LAMBERT Academic Publishing Mai 2017, 2017

3330320710 / 9783330320710

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This item is printed on demand - Print on Demand Titel. Neuware -The present research work is on gastro retentive floating matrix tablet of Quetiapine fumarate by using various hydrophilic polymers. The formulation was developed by using different concentrations of polymers of various grades of HPMC. Then Gas generating agent sodium bicarbonate concentration was optimized. The formulation blend was subjected to various pre-formulation studies, and all the formulations were found to be good indicating that the powder blend has good flow properties. Among the different control release polymers, HPMC K100M was showing highest drug release retarding capacity. F2 was showing the satisfactory results. For F2 formulation diffusion exponent n value is in between 0.45 to 0.89 so they are following non fickianan molous diffusion model. Higuchi plot for F2 formulation is having good correlation values so the drug is releasing diffusion mechanism; they were unable to retard drug release up to 12 hrs. This book, therefore, benefits the M. Pharmacy project students those who are interested to work in GRDDS.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 72 pp. Englisch.

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Title
Formulation and Evaluation of Floating Tablets of Quetiapine Fumarate
Author
Gangadi Jayapal Reddy
Publisher
LAP LAMBERT Academic Publishing Mai 2017
Publication year
2017
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3330320710
ISBN 13
9783330320710
Item weight
125 grams
Dimensions
220x150x5 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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