Fabrication of SR Matrix Tablet for Arthritis Treatment

Language: English

Published by LAP LAMBERT Academic Publishing, 2017

333032466X / 9783330324664

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Leflunomide is a disease modifying anti-rheumatic drug (DMARD), which effectively reduces the signs and symptoms of active rheumatoid arthritis (RA) in adults, while inhibiting joint damage and improving physical function. Direct compression was employed for the formulation of tablets. The powder blends of different tablet formulations were screened for preformulation studies like angle of repose, loose bulk density, tapped density, compressibility index and hausner's ratio. The tablets were tested for physical characteristics such as thickness, hardness, friability, weight variation and drug content. The matrix swelling behavior was also investigated. As the time increases, the swelling index was increased; later on it decreases gradually due to dissolution of outermost gelled layer of tablet into dissolution medium. All the evaluated physical parameters of the fabricated tablets were found to be within the acceptable limits.…

Seller Inventory # 9783330324664

Title
Fabrication of SR Matrix Tablet for Arthritis Treatment
Author
Payal Deepak
Publisher
LAP LAMBERT Academic Publishing
Publication year
2017
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
333032466X
ISBN 13
9783330324664
Item weight
161 grams
Dimensions
220x150x7 mm

AHA-BUCH GmbH

Einbeck, Germany

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