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Fabrication of SR Matrix Tablet for Arthritis Treatment - Softcover

 
9783330324664: Fabrication of SR Matrix Tablet for Arthritis Treatment

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Leflunomide is a disease modifying anti-rheumatic drug (DMARD), which effectively reduces the signs and symptoms of active rheumatoid arthritis (RA) in adults, while inhibiting joint damage and improving physical function. Direct compression was employed for the formulation of tablets. The powder blends of different tablet formulations were screened for preformulation studies like angle of repose, loose bulk density, tapped density, compressibility index and hausner’s ratio. The tablets were tested for physical characteristics such as thickness, hardness, friability, weight variation and drug content. The matrix swelling behavior was also investigated. As the time increases, the swelling index was increased; later on it decreases gradually due to dissolution of outermost gelled layer of tablet into dissolution medium. All the evaluated physical parameters of the fabricated tablets were found to be within the acceptable limits.

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Kumar, Praveen; Deepak, Payal
Published by LAP LAMBERT Academic Publishing, 2017
ISBN 10: 333032466X ISBN 13: 9783330324664
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Praveen Kumar
ISBN 10: 333032466X ISBN 13: 9783330324664
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Leflunomide is a disease modifying anti-rheumatic drug (DMARD), which effectively reduces the signs and symptoms of active rheumatoid arthritis (RA) in adults, while inhibiting joint damage and improving physical function. Direct compression was employed for the formulation of tablets. The powder blends of different tablet formulations were screened for preformulation studies like angle of repose, loose bulk density, tapped density, compressibility index and hausner's ratio. The tablets were tested for physical characteristics such as thickness, hardness, friability, weight variation and drug content. The matrix swelling behavior was also investigated. As the time increases, the swelling index was increased; later on it decreases gradually due to dissolution of outermost gelled layer of tablet into dissolution medium. All the evaluated physical parameters of the fabricated tablets were found to be within the acceptable limits. 96 pp. Englisch. Seller Inventory # 9783330324664

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Kumar, Praveen; Deepak, Payal
Published by LAP LAMBERT Academic Publishing, 2017
ISBN 10: 333032466X ISBN 13: 9783330324664
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Kumar, Praveen; Deepak, Payal
Published by LAP LAMBERT Academic Publishing, 2017
ISBN 10: 333032466X ISBN 13: 9783330324664
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Praveen Kumar|Payal Deepak
Published by LAP LAMBERT Academic Publishing, 2017
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kumar PraveenPraveen Kumar (S. D College of Pharmacy and vocational studies , Muzaffarnagar U.P. India. & Research scholar of Uttarakhand Technical University, Dehradun India.)Leflunomide is a disease modifying anti-rheumatic. Seller Inventory # 153204459

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Praveen Kumar
ISBN 10: 333032466X ISBN 13: 9783330324664
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Taschenbuch. Condition: Neu. Neuware -Leflunomide is a disease modifying anti-rheumatic drug (DMARD), which effectively reduces the signs and symptoms of active rheumatoid arthritis (RA) in adults, while inhibiting joint damage and improving physical function. Direct compression was employed for the formulation of tablets. The powder blends of different tablet formulations were screened for preformulation studies like angle of repose, loose bulk density, tapped density, compressibility index and hausner¿s ratio. The tablets were tested for physical characteristics such as thickness, hardness, friability, weight variation and drug content. The matrix swelling behavior was also investigated. As the time increases, the swelling index was increased; later on it decreases gradually due to dissolution of outermost gelled layer of tablet into dissolution medium. All the evaluated physical parameters of the fabricated tablets were found to be within the acceptable limits.Books on Demand GmbH, Überseering 33, 22297 Hamburg 96 pp. Englisch. Seller Inventory # 9783330324664

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Published by LAP LAMBERT Academic Publishing, 2017
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Leflunomide is a disease modifying anti-rheumatic drug (DMARD), which effectively reduces the signs and symptoms of active rheumatoid arthritis (RA) in adults, while inhibiting joint damage and improving physical function. Direct compression was employed for the formulation of tablets. The powder blends of different tablet formulations were screened for preformulation studies like angle of repose, loose bulk density, tapped density, compressibility index and hausner's ratio. The tablets were tested for physical characteristics such as thickness, hardness, friability, weight variation and drug content. The matrix swelling behavior was also investigated. As the time increases, the swelling index was increased; later on it decreases gradually due to dissolution of outermost gelled layer of tablet into dissolution medium. All the evaluated physical parameters of the fabricated tablets were found to be within the acceptable limits. Seller Inventory # 9783330324664

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Praveen Kumar
Published by LAP LAMBERT Academic Publishing, 2017
ISBN 10: 333032466X ISBN 13: 9783330324664
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Paperback. Condition: Brand New. 96 pages. 8.66x5.91x0.22 inches. In Stock. Seller Inventory # 333032466X

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