Exploring Privileged Heterocyclic Scaffolds:

Language: English

Published by LAP LAMBERT Academic Publishing Aug 2018, 2018

6139900891 / 9786139900893

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Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

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Softcover

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This item is printed on demand - Print on Demand Titel. Neuware -Inflammation is characterized by redness, heat, swelling, pain and sometimes loss of function of tissues. Cyclooxygenases (COXs) are mainly responsible for inflammation. Constitutive COX-1 is responsible for providing cytoprotection in gastrointestinal (GI) tract whereas inducible COX-2 facilitates inflammation. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat the signs and symptoms of inflammation. Traditional non-steroidal anti-inflammatory drugs (NSAIDs) such as Aspirin, Diclofenac, Flurbiprofen and Ibuprofen act via the inhibition of the COX-1 isoenzyme or the combined inhibition of COX-1 and COX-2 isoenzymes. However they show greater selectivity for COX-1 than COX-2 as well as produce serious side effect like hepatic toxicity. Therefore, it is urgently required to identify new targets that are essential for the design and development of novel anti-inflammatory agents as an alternative to NSAIDs. The relevant information provided in this manuscript can be found useful for drug design of novel anti-inflammatory agents having greater safety, selectivity and potency as well as lesser side effects.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 88 pp. Englisch.…

Seller Inventory # 9786139900893

Title
Exploring Privileged Heterocyclic Scaffolds:
Author
Rajeev Kharb
Publisher
LAP LAMBERT Academic Publishing Aug 2018
Publication year
2018
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6139900891
ISBN 13
9786139900893
Item weight
149 grams
Dimensions
220x150x6 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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