Exploring Privileged Heterocyclic Scaffolds:: Their Scope as Novel Anti-Inflammatory Drug Candidates - Softcover
Synopsis
Inflammation is characterized by redness, heat, swelling, pain and sometimes loss of function of tissues. Cyclooxygenases (COXs) are mainly responsible for inflammation. Constitutive COX-1 is responsible for providing cytoprotection in gastrointestinal (GI) tract whereas inducible COX-2 facilitates inflammation. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat the signs and symptoms of inflammation. Traditional non-steroidal anti-inflammatory drugs (NSAIDs) such as Aspirin, Diclofenac, Flurbiprofen and Ibuprofen act via the inhibition of the COX-1 isoenzyme or the combined inhibition of COX-1 and COX-2 isoenzymes. However they show greater selectivity for COX-1 than COX-2 as well as produce serious side effect like hepatic toxicity. Therefore, it is urgently required to identify new targets that are essential for the design and development of novel anti-inflammatory agents as an alternative to NSAIDs. The relevant information provided in this manuscript can be found useful for drug design of novel anti-inflammatory agents having greater safety, selectivity and potency as well as lesser side effects.
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Exploring Privileged Heterocyclic Scaffolds:
Published by
LAP LAMBERT Academic Publishing Aug 2018, 2018
ISBN 10: 6139900891
ISBN 13: 9786139900893
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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Inflammation is characterized by redness, heat, swelling, pain and sometimes loss of function of tissues. Cyclooxygenases (COXs) are mainly responsible for inflammation. Constitutive COX-1 is responsible for providing cytoprotection in gastrointestinal (GI) tract whereas inducible COX-2 facilitates inflammation. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat the signs and symptoms of inflammation. Traditional non-steroidal anti-inflammatory drugs (NSAIDs) such as Aspirin, Diclofenac, Flurbiprofen and Ibuprofen act via the inhibition of the COX-1 isoenzyme or the combined inhibition of COX-1 and COX-2 isoenzymes. However they show greater selectivity for COX-1 than COX-2 as well as produce serious side effect like hepatic toxicity. Therefore, it is urgently required to identify new targets that are essential for the design and development of novel anti-inflammatory agents as an alternative to NSAIDs. The relevant information provided in this manuscript can be found useful for drug design of novel anti-inflammatory agents having greater safety, selectivity and potency as well as lesser side effects. 88 pp. Englisch. Seller Inventory # 9786139900893
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Exploring Privileged Heterocyclic Scaffolds:: Their Scope as Novel Anti-Inflammatory Drug Candidates
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 6139900891
ISBN 13: 9786139900893
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Paperback. Condition: Brand New. 88 pages. 8.66x5.91x0.20 inches. In Stock. Seller Inventory # zk6139900891
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Exploring Privileged Heterocyclic Scaffolds:
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 6139900891
ISBN 13: 9786139900893
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kharb RajeevDr. Rajeev Kharb is working as Associate Professor in Amity Institute of Pharmacy, Amity University, Noida, India. He has 14 years of experience in teaching and research. He has 30 publications and written 3 books. His ar. Seller Inventory # 385876558
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Exploring Privileged Heterocyclic Scaffolds:
Published by
LAP LAMBERT Academic Publishing Aug 2018, 2018
ISBN 10: 6139900891
ISBN 13: 9786139900893
New
Taschenbuch
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Inflammation is characterized by redness, heat, swelling, pain and sometimes loss of function of tissues. Cyclooxygenases (COXs) are mainly responsible for inflammation. Constitutive COX-1 is responsible for providing cytoprotection in gastrointestinal (GI) tract whereas inducible COX-2 facilitates inflammation. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat the signs and symptoms of inflammation. Traditional non-steroidal anti-inflammatory drugs (NSAIDs) such as Aspirin, Diclofenac, Flurbiprofen and Ibuprofen act via the inhibition of the COX-1 isoenzyme or the combined inhibition of COX-1 and COX-2 isoenzymes. However they show greater selectivity for COX-1 than COX-2 as well as produce serious side effect like hepatic toxicity. Therefore, it is urgently required to identify new targets that are essential for the design and development of novel anti-inflammatory agents as an alternative to NSAIDs. The relevant information provided in this manuscript can be found useful for drug design of novel anti-inflammatory agents having greater safety, selectivity and potency as well as lesser side effects.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 88 pp. Englisch. Seller Inventory # 9786139900893
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Exploring Privileged Heterocyclic Scaffolds: : Their Scope as Novel Anti-Inflammatory Drug Candidates
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 6139900891
ISBN 13: 9786139900893
New
Taschenbuch
Seller: AHA-BUCH GmbH, Einbeck, Germany
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Inflammation is characterized by redness, heat, swelling, pain and sometimes loss of function of tissues. Cyclooxygenases (COXs) are mainly responsible for inflammation. Constitutive COX-1 is responsible for providing cytoprotection in gastrointestinal (GI) tract whereas inducible COX-2 facilitates inflammation. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat the signs and symptoms of inflammation. Traditional non-steroidal anti-inflammatory drugs (NSAIDs) such as Aspirin, Diclofenac, Flurbiprofen and Ibuprofen act via the inhibition of the COX-1 isoenzyme or the combined inhibition of COX-1 and COX-2 isoenzymes. However they show greater selectivity for COX-1 than COX-2 as well as produce serious side effect like hepatic toxicity. Therefore, it is urgently required to identify new targets that are essential for the design and development of novel anti-inflammatory agents as an alternative to NSAIDs. The relevant information provided in this manuscript can be found useful for drug design of novel anti-inflammatory agents having greater safety, selectivity and potency as well as lesser side effects. Seller Inventory # 9786139900893
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Exploring Privileged Heterocyclic Scaffolds: | Their Scope as Novel Anti-Inflammatory Drug Candidates
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 6139900891
ISBN 13: 9786139900893
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Taschenbuch. Condition: Neu. Exploring Privileged Heterocyclic Scaffolds: | Their Scope as Novel Anti-Inflammatory Drug Candidates | Rajeev Kharb | Taschenbuch | 88 S. | Englisch | 2018 | LAP LAMBERT Academic Publishing | EAN 9786139900893 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 114472757