Exploration of interface between graphene sheets and thrombus biology

Language: English

Published by LAP LAMBERT Academic Publishing, 2016

3659890685 / 9783659890680

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Softcover

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nach der Bestellung gedruckt Neuware - Printed after ordering - Graphene, a two dimensional carbon-based nanomaterial, have attracted great research interest and are of paramount importance in numerous fields including biomedical areas. With rapid surge in research and development activities on carbon nanomaterials, risks associated with them are reasons for serious concern among scientific community. Any material injected intravenously is bound to encounter and possibly interact with blood cells, particularly platelets which are known to be highly responsive and RBCs, cells present in abundance in blood, much before the nanomaterial reaches target tissues. We evaluated the effect of graphene oxide (GO) on platelet activity and found GO can potentially activate platelets. GO-induced platelet activation could be attributed to release of intracellular free calcium from cytosolic stores and activation of non-receptor protein tyrosine kinases of Src family in platelets. Contrasting the observation with GO,amine modified graphene (G-NH2) not shown any stimulatory action towards platelets. Thus, G-NH2 can be a safer alternative to GO, with potential biomedical applications in areas like imaging, sensing, drug delivery as well as photothermal therapy.…

Seller Inventory # 9783659890680

Title
Exploration of interface between graphene sheets and thrombus biology
Author
Sunil Kumar Singh
Publisher
LAP LAMBERT Academic Publishing
Publication year
2016
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659890685
ISBN 13
9783659890680
Item weight
191 grams
Dimensions
220x150x8 mm

AHA-BUCH GmbH

Einbeck, Germany

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