Endocrine Disruptors - A Major Medical Challenge
Language: English
Published by LAP LAMBERT Academic Publishing Okt 2010, 2010
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 42.64
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -Exposure to Endocrine Disruptors (EDs) with estrogen like activities during late pregnancy can induce temporal and specific alterations in gene expression profiles in the uteri of dams and neonates, most likely reflecting the temporal susceptibility of the reproductive tract to estrogenic EDs in which some estrogen responsive expressed markedly in the uterus of neonates. In addition, results from our experiments demonstrate the involvement of various signaling pathways in response to E2 and EDs in vitro and in vivo. These EDs may trigger the induction of CaBP-9k, a useful biomarker for screening the estrogenicity of EDs, via an estrogen receptor mediated pathways in animal and cellular models. Furthermore, non-genomic pathways appear to be involved in the induction of CaBP-9k expression by estrogen or estrogenic compounds. Taken together, these results indicated that both genomic and non- genomic actions are required to induce and modulate an ED- response in vitro and in vivo in which non- genomic responses occur rapidly, often within minutes of exposure, whereas genomic responses are delayed and require at least several hours to become established. 116 pp. Englisch.…
Seller Inventory # 9783843370233
- Title
- Endocrine Disruptors - A Major Medical Challenge
- Author
- Hoang Vu Dang
- Publisher
- LAP LAMBERT Academic Publishing Okt 2010
- Publication year
- 2010
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3843370230
- ISBN 13
- 9783843370233
- Item weight
- 191 grams
- Dimensions
- 220x150x7 mm
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About the Author
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BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
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