This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,650grams, ISBN:9780132025652.

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Bibliographic Details

Title

The Design and Analysis of Sequential Clinical Trials

Publisher

Ellis Horwood Ltd , Publisher

Publication Date

1992

Language

English

ISBN 10

0132025655

ISBN 13

9780132025652

Binding

Hardcover

Condition

Good

Seller catalogs

Mathematics

About this title

Synopsis

This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include –spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.

Review

"...This book is clear, it provides many details and is well written..." (Statistical Methods in Medical Research, No.11, 2002)

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