The Design and Analysis of Sequential Clinical Trials

Whitehead, John

ISBN 10: 0132025655 / ISBN 13: 9780132025652

Published by U.S.A.: Ellis Horwood Ltd, 1992

About this Item

2nd edition hardback book in near fine condition.

Seller Inventory # 33071

Bibliographic Details

• Title: The Design and Analysis of Sequential Clinical Trials
• Publisher: U.S.A.: Ellis Horwood Ltd
• Publication Date: 1992
• Language: English
• ISBN 10: 0132025655
• ISBN 13: 9780132025652
• Binding: Hardcover
• Edition: 2nd Edition
• Condition: Near Fine
• Seller catalogs:
  • psychology
  • social history
  • mathematics

About this title

Synopsis

This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include –spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.

Review

"...This book is clear, it provides many details and is well written..." (Statistical Methods in Medical Research, No.11, 2002)