Title: The Design and Analysis of Sequential Clinical Trials (Mathematics & Its Applications)
Publisher: Ellis Horwood Ltd
Publication Date: 1992
Language: English
ISBN 10: 0132025655
ISBN 13: 9780132025652
Binding: hardcover
Condition: As New

About this title

Synopsis

This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include –spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.

Review

"...This book is clear, it provides many details and is well written..." (Statistical Methods in Medical Research, No.11, 2002)

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